Detailed information NTG0173544

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: BSR14_RS08240
• Genome accession: NZ_CP018186
• Coordinates: 1794389..1796494 (-)
• Length: 701 a.a.
• NCBI ID: WP_049529235.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain ICDC1
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1789389..1801494

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSR14_RS08210 (BSR14_08290)	pptB	1789731..1790768 (-)	1038	WP_156209918.1	ABC transporter permease	Regulator
BSR14_RS08215 (BSR14_08295)	pptA	1790765..1791496 (-)	732	WP_156209919.1	ABC transporter ATP-binding protein	Regulator
BSR14_RS08220 (BSR14_08300)	-	1791561..1791980 (+)	420	WP_156209920.1	HIT family protein	-
BSR14_RS08225 (BSR14_08305)	-	1791977..1792276 (+)	300	WP_156209921.1	hypothetical protein	-
BSR14_RS08230 (BSR14_08310)	-	1792743..1793108 (-)	366	WP_156209922.1	hypothetical protein	-
BSR14_RS08235 (BSR14_08315)	-	1793201..1793809 (-)	609	WP_002884297.1	DUF4230 domain-containing protein	-
BSR14_RS10565	-	1793827..1793952 (-)	126	WP_002884447.1	hypothetical protein	-
BSR14_RS08240 (BSR14_08320)	clpE	1794389..1796494 (-)	2106	WP_049529235.1	AAA family ATPase	Regulator
BSR14_RS08245 (BSR14_08325)	-	1797220..1797474 (-)	255	WP_014634942.1	Txe/YoeB family addiction module toxin	-
BSR14_RS08250 (BSR14_08330)	-	1797478..1797732 (-)	255	WP_013991075.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
BSR14_RS08255 (BSR14_08335)	-	1797894..1800893 (-)	3000	WP_156209923.1	type I restriction endonuclease subunit R	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77405.33 Da
• Isoelectric Point: 4.7499

>NTDB_id=173544 BSR14_RS08240 WP_049529235.1 1794389..1796494(-) (clpE) [Streptococcus salivarius strain ICDC1]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQHQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDEVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTEDLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide

• Length: 2106 bp

>NTDB_id=173544 BSR14_RS08240 WP_049529235.1 1794389..1796494(-) (clpE) [Streptococcus salivarius strain ICDC1]
ATGAACAACAACTTTAACAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCTATTTACCGTCAAACAGGTCAATTGCCTGGTAACG
AAGGTGAAGCAGTCAACCCAACTCAACATCAAGGTAAAGGACCTAAACAAGATGGTATTCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACTAAGAATAACCCAGTCCTTGTCGGGGACGCTGGTGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCTC
AAGCTATCGTTAATGGTGATGTCCCAGCTGCTATCAAGAACAAAGAAATCATCTCAATCGATATTTCTGGACTTGAAGCT
GGTACGCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAATATTATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCTGGTAGCACTGGCGATGGTCAAGGGTCTAAAGGTCTTGCTGATATCT
TGAAACCTGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AACGCTGCTCTTGCGCGTCGTTTCAACGAAGTTAAGGTTAATGCTCCTTCTGCTGAAGATACTTTCAAGATTCTCCAAGG
TATTCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGAAGTCTTGAAAGCAGCAGTAGATTTCTCTGTGC
AATACATTCCACAACGTAGCCTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCGGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAACGCTAAGGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCACACAGAAGACCTTAAAG
TCACTGCAACTGTTAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCAGTGTCACAAATGGGTGCAACTGAT
ATCGAACGTTTGAAAGATATGGGTCACCGTTTGCAAACTAAGGTTATCGGTCAAGATAAAGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATTGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGAACTAAAGATGCTATCATTCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATCGTCCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTTATCA
CACTTCTTCTCCAAGTTTTGGATGATGGTCGTTTGACTGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATCGCAACTTCAAACGCAGGATTTGGCTATGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACTCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGACGGTGTCTTGG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (608-678)

• AAA lid domain (AAA_lid_9) (257-351)

• AAA domain (Cdc48 subfamily) (AAA_2) (441-601)

• ATPase family associated with various cellular activities (AAA) (AAA) (116-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.857	99.857	0.468
clpC	Lactococcus lactis subsp. cremoris KW2	49.54	93.01	0.461
clpE	Streptococcus pneumoniae D39	48.678	91.726	0.447
clpE	Streptococcus pneumoniae R6	48.678	91.726	0.447
clpE	Streptococcus pneumoniae Rx1	48.678	91.726	0.447
clpE	Streptococcus pneumoniae TIGR4	48.442	91.583	0.444
clpC	Bacillus subtilis subsp. subtilis str. 168	45.538	92.725	0.422
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.243	92.867	0.392
clpC	Streptococcus pneumoniae TIGR4	43.248	88.73	0.384
clpC	Streptococcus pneumoniae Rx1	43.248	88.73	0.384
clpC	Streptococcus pneumoniae D39	43.248	88.73	0.384
clpC	Streptococcus thermophilus LMD-9	42.95	88.017	0.378
clpC	Streptococcus thermophilus LMG 18311	42.811	88.302	0.378
clpC	Streptococcus mutans UA159	42.332	89.301	0.378