Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   AS588_RS09815 Genome accession   NZ_CP014700
Coordinates   2123701..2124357 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus amyloliquefaciens strain S499     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2118701..2129357
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AS588_RS09800 (AS588_09800) spxH 2118940..2119842 (+) 903 WP_003155024.1 protease adaptor protein SpxH -
  AS588_RS20095 - 2120128..2120295 (+) 168 WP_003155026.1 hypothetical protein -
  AS588_RS09805 (AS588_09805) pepF 2120333..2122162 (-) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  AS588_RS09810 (AS588_09810) - 2122390..2123550 (-) 1161 WP_015388448.1 competence protein CoiA family protein -
  AS588_RS09815 (AS588_09815) mecA 2123701..2124357 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  AS588_RS20100 - 2124340..2124450 (-) 111 Protein_1995 adaptor protein MecA -
  AS588_RS09820 (AS588_09820) - 2124633..2125289 (+) 657 WP_003155033.1 TerC family protein -
  AS588_RS09825 (AS588_09825) spx 2125347..2125742 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  AS588_RS09830 (AS588_09830) - 2125921..2126499 (-) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  AS588_RS09835 (AS588_09835) - 2126617..2127804 (-) 1188 WP_003155036.1 putative glycoside hydrolase -
  AS588_RS09840 (AS588_09840) oppF 2127911..2128828 (-) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=173425 AS588_RS09815 WP_003155032.1 2123701..2124357(-) (mecA) [Bacillus amyloliquefaciens strain S499]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=173425 AS588_RS09815 WP_003155032.1 2123701..2124357(-) (mecA) [Bacillus amyloliquefaciens strain S499]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment