Detailed information NTG0173360

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: A0O21_RS06910
• Genome accession: NZ_CP014699
• Coordinates: 1508435..1509520 (-)
• Length: 361 a.a.
• NCBI ID: WP_067063446.1
• Uniprot ID: A0A172Q8Q3
• Organism: Streptococcus pantholopis strain TA 26
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1503435..1514520

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A0O21_RS06885 (A0O21_06885)	-	1503922..1504452 (-)	531	WP_067063432.1	VanZ family protein	-
A0O21_RS06890 (A0O21_06890)	rlmN	1504449..1505528 (-)	1080	WP_067063434.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
A0O21_RS06895 (A0O21_06895)	-	1505532..1506119 (-)	588	WP_067063436.1	YutD family protein	-
A0O21_RS06900 (A0O21_06900)	-	1506586..1507950 (-)	1365	WP_067063439.1	bifunctional metallophosphatase/5'-nucleotidase	-
A0O21_RS06905 (A0O21_06905)	-	1508053..1508301 (-)	249	WP_067063443.1	DUF3923 family protein	-
A0O21_RS06910 (A0O21_06910)	sepM	1508435..1509520 (-)	1086	WP_067063446.1	SepM family pheromone-processing serine protease	Regulator
A0O21_RS06915 (A0O21_06915)	coaD	1509498..1509998 (-)	501	WP_067063450.1	pantetheine-phosphate adenylyltransferase	-
A0O21_RS06920 (A0O21_06920)	rsmD	1509988..1510527 (-)	540	WP_067063453.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
A0O21_RS06925 (A0O21_06925)	asnA	1510737..1511729 (-)	993	WP_067063455.1	aspartate--ammonia ligase	-
A0O21_RS06930 (A0O21_06930)	-	1512421..1513506 (-)	1086	WP_067063458.1	MmcQ/YjbR family DNA-binding protein	-
A0O21_RS06935 (A0O21_06935)	-	1513638..1514519 (+)	882	WP_067065212.1	sulfite exporter TauE/SafE family protein	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39313.35 Da
• Isoelectric Point: 4.2021

>NTDB_id=173360 A0O21_RS06910 WP_067063446.1 1508435..1509520(-) (sepM) [Streptococcus pantholopis strain TA 26]
MKILQVFSSNLKALRQWIKQFKWWLIGALAAFLLLFSLFVPLPYYLEMPGGAYDIRSVLTVDDRKDDQEGSYNFVAVSMS
QATLAQLIYGWLTPFTEITSMQETTGGYSNDDYIRMNQFYMETSQNNAVYQALSLAGEEVSLDYMGVYVLNVNENSSFKG
ILQLADTVTGVNSRTFSSSADLIDYVSGLELGEPVTVQYTSDGKAKEAEGKIIRLENGKNGIGIGLVDHTEVNSDKDIVF
STDGVGGPSAGLMFTLDIYDQLTEEDLRQGRVIAGTGTIEKDGSVGDIGGAALKVVAADKAGAEIFFVPNNPVDEAVLKA
DPAAKTNYEEAAAAAKELGSKMKIVPVTNVQEAIDYLRKQD

Nucleotide

• Length: 1086 bp

>NTDB_id=173360 A0O21_RS06910 WP_067063446.1 1508435..1509520(-) (sepM) [Streptococcus pantholopis strain TA 26]
GTGAAGATTTTACAAGTCTTTAGTTCAAATCTAAAAGCACTGAGACAGTGGATCAAGCAGTTTAAGTGGTGGCTAATCGG
TGCTCTGGCAGCGTTTTTGCTGCTTTTTAGCCTTTTTGTACCGCTTCCCTATTATTTAGAGATGCCGGGCGGTGCTTATG
ACATTCGTTCGGTTTTGACAGTTGATGACCGGAAAGATGATCAGGAGGGTTCCTATAATTTTGTGGCTGTCAGTATGAGT
CAGGCCACTCTGGCCCAGCTGATTTACGGCTGGCTGACCCCCTTCACTGAAATTACCAGTATGCAGGAGACAACCGGGGG
CTACAGTAATGATGATTATATCAGAATGAATCAGTTTTACATGGAAACCTCACAGAATAATGCTGTTTATCAGGCTCTCA
GTTTGGCCGGTGAAGAAGTCAGTCTTGACTATATGGGGGTCTATGTCCTTAATGTCAATGAAAACTCCAGTTTTAAAGGA
ATCCTTCAGCTGGCTGATACAGTCACAGGCGTTAACAGCCGGACTTTTAGCAGCTCTGCCGACCTTATTGACTATGTTAG
CGGCCTGGAATTGGGGGAACCGGTAACCGTTCAGTATACATCTGATGGCAAGGCTAAAGAGGCAGAAGGAAAAATCATCA
GGCTGGAAAATGGGAAAAATGGTATTGGCATTGGTCTGGTCGATCATACAGAAGTTAATTCGGATAAGGATATTGTTTTT
TCAACGGATGGTGTCGGAGGTCCCAGTGCTGGCTTAATGTTTACCTTAGATATTTATGACCAGCTGACTGAGGAGGATCT
GCGGCAGGGACGTGTGATTGCCGGAACTGGAACAATTGAAAAGGATGGCTCAGTCGGTGATATCGGCGGCGCTGCTTTGA
AGGTTGTTGCAGCGGATAAGGCTGGAGCAGAGATCTTCTTTGTTCCTAATAACCCTGTAGATGAAGCTGTTTTAAAAGCT
GACCCAGCTGCTAAAACGAATTATGAAGAAGCTGCAGCAGCAGCTAAAGAGCTGGGCAGCAAGATGAAGATTGTTCCTGT
GACCAATGTTCAGGAAGCTATCGATTATTTAAGAAAGCAGGATTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (247-312)

• PDZ domain (PDZ_2) (144-209)

3D structure

• AlphaFold DB: A0A172Q8Q3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	70.468	94.737	0.668