Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   AZE34_RS09295 Genome accession   NZ_CP014567
Coordinates   1887128..1887844 (-) Length   238 a.a.
NCBI ID   WP_265475241.1    Uniprot ID   A0A3S7GWR1
Organism   Staphylococcus hominis strain C34847     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1882128..1892844
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AZE34_RS09270 (AZE34_09080) - 1882158..1882796 (+) 639 WP_017175284.1 redox-sensing transcriptional repressor Rex -
  AZE34_RS09275 (AZE34_09085) - 1882863..1883021 (+) 159 Protein_1815 sulfurtransferase TusA family protein -
  AZE34_RS09280 (AZE34_09090) - 1883131..1884375 (+) 1245 WP_017175282.1 ammonium transporter -
  AZE34_RS09285 (AZE34_09095) - 1884630..1886117 (+) 1488 WP_017175281.1 sucrose-6-phosphate hydrolase -
  AZE34_RS09290 (AZE34_09100) - 1886118..1887077 (+) 960 WP_017175280.1 carbohydrate kinase family protein -
  AZE34_RS09295 (AZE34_09105) agrA 1887128..1887844 (-) 717 WP_265475241.1 quorum-sensing response regulator AgrA Regulator
  AZE34_RS09300 (AZE34_09110) agrC 1887857..1889146 (-) 1290 WP_017175279.1 quorum-sensing sensor histidine kinase AgrC -
  AZE34_RS09305 (AZE34_09115) agrD 1889171..1889311 (-) 141 WP_017175278.1 cyclic lactone autoinducer peptide AgrD -
  AZE34_RS09310 (AZE34_09120) - 1889314..1889880 (-) 567 WP_017175277.1 accessory gene regulator AgrB -
  AZE34_RS09315 (AZE34_09125) - 1890582..1891367 (-) 786 WP_017175276.1 carbon-nitrogen family hydrolase -
  AZE34_RS09320 (AZE34_09130) - 1891498..1892121 (-) 624 WP_017175275.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27888.84 Da        Isoelectric Point: 5.2104

>NTDB_id=172518 AZE34_RS09295 WP_265475241.1 1887128..1887844(-) (agrA) [Staphylococcus hominis strain C34847]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEIIEQSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPNQLKMRIIDCIETAHTRLKLLSKESNVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDDRFFRCHNSFVVNRHNIDSVDSKERIVTFRNGEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=172518 AZE34_RS09295 WP_265475241.1 1887128..1887844(-) (agrA) [Staphylococcus hominis strain C34847]
ATGAAAATATTCATTTGTGAAGACGATGTGAAACAACGTGAAAATATGGTTTCAATTATTAATAACTATATAATGATTGA
AGAAAAACCGATGGAAATAGCGTTAGCGACAGATGATCCTTATGAAATTATTGAACAGTCAAAAGAAATGAATGATGTTG
GATGTTATTTTTTAGATATACAATTAGAAGCTGATATTAACGGTATTAAACTTGGAAGTGAAATTCGAAAGTATGATCCT
ATTGGGAATATCATCTTTGTTACAAGTCATAGTGAACTCACTTACCTAACATTTGTCTATAAGGTATCTGCAATGGATTT
TATTTTTAAAGATGATCCTAATCAACTTAAAATGCGAATAATAGATTGTATTGAAACTGCTCATACACGTTTAAAATTAC
TTTCAAAAGAAAGTAATGTTGAGACAATTGAATTAAAGCGTGGTAGCAATTCAATATATGTACAATATGATGATGTCATG
TTCTTTGAATCGTCTACAAAATCCCATCGTTTAATTGCGCATCTTGATAACCGTCAGATTGAATTCTACGGAAATCTTAA
AGAATTAGCACAACTCGATGATCGTTTTTTCAGATGTCACAATAGTTTTGTTGTAAATCGCCATAATATCGATTCAGTCG
ATTCTAAAGAACGAATTGTAACTTTCAGAAATGGTGAGCATTGCTATGCCTCTGTACGTAATGTTAAAAAGATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3S7GWR1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

86.975

100

0.87

Multiple sequence alignment