Detailed information NTG0172387

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: A2U21_RS07495
• Genome accession: NZ_CP018034
• Coordinates: 1437674..1440247 (+)
• Length: 857 a.a.
• NCBI ID: WP_021109404.1
• Uniprot ID: -
• Organism: Glaesserella parasuis str. Nagasaki
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1432674..1445247

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2U21_RS07475 (A2U21_07210)	znuB	1433461..1434246 (-)	786	WP_016528135.1	zinc ABC transporter permease subunit ZnuB	-
A2U21_RS07480 (A2U21_07215)	znuC	1434257..1435042 (-)	786	WP_021109406.1	zinc ABC transporter ATP-binding protein ZnuC	-
A2U21_RS07485 (A2U21_07220)	mepM	1435182..1436675 (+)	1494	WP_010785789.1	murein DD-endopeptidase MepM	-
A2U21_RS07490 (A2U21_07225)	dsbC	1436687..1437370 (+)	684	WP_021109405.1	bifunctional protein-disulfide isomerase/oxidoreductase DsbC	-
A2U21_RS07495 (A2U21_07230)	clpC	1437674..1440247 (+)	2574	WP_021109404.1	ATP-dependent chaperone ClpB	Regulator
A2U21_RS07500 (A2U21_07235)	-	1440365..1441027 (+)	663	WP_016528139.1	Bax inhibitor-1 family protein	-
A2U21_RS07505 (A2U21_07240)	polA	1441095..1443959 (-)	2865	WP_005713856.1	DNA polymerase I	-
A2U21_RS07510 (A2U21_07245)	hxpB	1444106..1444753 (-)	648	WP_021109403.1	hexitol phosphatase HxpB	-

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 95822.15 Da
• Isoelectric Point: 5.1143

>NTDB_id=172387 A2U21_RS07495 WP_021109404.1 1437674..1440247(+) (clpC) [Glaesserella parasuis str. Nagasaki]
MNIDKFTSKFQSAIADAQSLAVGKDNPYIEPAHLMLALLKQNDGSITPLVTSLNVQPNRLSSELDGIISRLPQVQGGNTQ
PSQQLFRLLNQCDKLSQQFGDSFISSELFVLAALEDNGDLGKLLKNLGLTKEKVTAAIQQIRGGESVNNQNAEETRQALQ
KYTIDLTERAKAGKLDPVIGRDEEIRRTVQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQCIVNGEVPEGLKNKRVLSLDM
GALIAGAKYRGEFEERLKAVLNELAKEEGQVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYRQY
IEKDAALERRFQKVLVDEPTVEDTIAILRGLKERYEIHHHVQITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASSLR
MEIDSKPEPLDKLERRIIQLKLERQALQKEEDEASRQRLAKLDEDLTAREREYAELEEVWKAEKSALLGTQHIKTELENA
RIEMDQARRENNFEKMSELQYGKIPALEKQLQEAVKREEEGGENHLLRTKVTDEEIAEVLSKATGIPVSKMMEGEKEKLL
RMEEVLHKRVIGQSEAVDAVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLANFLFDDQDAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVVLLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSHLIQENAENMSYDEMKTIVMNVVGQHFRPEFINRIDETVVFHPLDKENIRAIARIQLERLIKRMAERGYEVTVTDAAV
DHIGEAGFDPLFGARPLKRAIQQELENTLAQQILSGKLLPNSPVTVDYREGRVVAVQ

Nucleotide

• Length: 2574 bp

>NTDB_id=172387 A2U21_RS07495 WP_021109404.1 1437674..1440247(+) (clpC) [Glaesserella parasuis str. Nagasaki]
ATGAATATTGATAAATTTACCAGCAAATTCCAATCTGCAATTGCCGATGCACAATCTTTAGCCGTTGGCAAAGATAATCC
CTATATTGAACCGGCCCATTTAATGCTTGCCTTGTTAAAGCAAAATGATGGCTCAATCACACCGCTTGTTACCAGTTTAA
ATGTGCAACCGAACCGTTTAAGCAGTGAACTTGATGGCATTATCAGCCGTTTACCGCAGGTGCAAGGGGGCAATACTCAG
CCGTCGCAACAACTTTTTCGCTTGTTAAATCAATGCGATAAATTGTCGCAACAGTTTGGTGATAGCTTTATTTCATCAGA
GCTGTTTGTACTTGCGGCACTTGAAGATAACGGTGATTTAGGCAAGTTATTGAAAAACTTAGGTTTAACCAAAGAGAAGG
TGACAGCCGCCATTCAACAAATTCGTGGAGGGGAGAGCGTGAATAATCAAAATGCAGAAGAAACGAGACAAGCGTTACAA
AAATATACCATTGATTTAACTGAACGGGCTAAAGCAGGCAAACTTGATCCTGTGATCGGGCGTGATGAAGAGATCCGCCG
TACGGTGCAAGTATTGCAACGCCGTACTAAAAATAACCCAGTGCTTATCGGTGAACCTGGTGTGGGGAAAACGGCGATTG
TCGAAGGTTTAGCACAATGTATTGTCAATGGCGAAGTGCCTGAGGGTTTGAAGAACAAACGGGTATTGTCGTTGGATATG
GGAGCGTTAATTGCAGGAGCAAAATACCGCGGTGAGTTTGAAGAACGTTTGAAAGCGGTATTAAATGAACTTGCCAAAGA
AGAAGGGCAAGTGATCCTGTTTATTGATGAAATTCATACGATGGTTGGGGCAGGTAAAACCGATGGAGCGATGGACGCTG
GTAACTTGTTGAAACCGTCCCTTGCCCGTGGTGAGTTGCACTGTGTCGGGGCGACAACCTTAGATGAATACCGTCAGTAT
ATTGAAAAAGATGCAGCTCTGGAGCGTCGTTTCCAAAAAGTGTTGGTTGATGAGCCGACGGTGGAAGATACCATTGCGAT
TTTGCGTGGTTTGAAAGAACGTTACGAAATTCACCATCACGTTCAAATTACCGACCCTGCGATTGTAGCGGCAGCAACTC
TTTCGCACCGCTATATTTCAGATCGCCAGTTACCCGATAAAGCGATTGATTTAATTGATGAAGCGGCTTCCAGCTTGCGT
ATGGAAATCGACTCTAAACCAGAGCCGTTAGATAAACTTGAACGCCGTATCATTCAGTTGAAATTAGAGCGTCAAGCGTT
ACAGAAAGAAGAAGATGAAGCCAGCCGTCAGCGTCTTGCAAAATTAGACGAGGATCTGACCGCTCGTGAACGTGAATATG
CGGAGCTGGAAGAAGTATGGAAAGCAGAAAAATCCGCTCTATTAGGCACGCAACACATTAAAACCGAGTTGGAAAATGCC
CGAATTGAAATGGATCAGGCTCGCCGTGAGAATAACTTTGAAAAAATGTCAGAGTTGCAATACGGCAAAATTCCGGCCCT
TGAGAAGCAGTTGCAAGAAGCGGTAAAACGTGAAGAAGAGGGCGGTGAAAATCATCTGTTACGCACCAAAGTGACCGATG
AAGAAATTGCCGAAGTGCTGTCTAAAGCCACGGGTATCCCTGTATCCAAAATGATGGAGGGGGAAAAAGAGAAACTATTG
CGAATGGAAGAAGTGCTACACAAACGAGTAATCGGTCAAAGTGAAGCCGTTGATGCGGTAGCAAATGCGATCCGACGTAG
TCGAGCAGGCTTGTCTGATCCAAATCGCCCTATCGGTTCATTCCTATTCTTAGGACCGACAGGCGTAGGGAAAACAGAGC
TTTGCAAAACATTAGCCAACTTCCTATTTGACGACCAAGATGCGATGGTGCGGATCGATATGTCCGAATTTATGGAAAAA
CATAGCGTATCTCGCTTAGTCGGTGCACCACCAGGATATGTCGGCTATGAAGAAGGCGGATACTTAACCGAAGCAGTTCG
CCGTCGTCCATATTCGGTTGTGTTGCTCGATGAAGTAGAAAAAGCTCACCCGGATGTGTTCAACATTTTATTGCAGGTGC
TTGATGATGGTCGTTTAACTGACGGACAAGGTCGTACGGTAGATTTCCGTAATACGGTCGTCATTATGACATCAAACTTA
GGTTCGCATTTAATTCAAGAGAATGCGGAAAATATGAGTTACGATGAAATGAAAACTATCGTGATGAATGTGGTTGGGCA
ACATTTCCGCCCTGAATTTATCAACCGTATTGATGAAACTGTGGTATTCCACCCATTAGATAAAGAAAATATCCGTGCGA
TTGCTAGAATTCAGCTTGAACGTTTAATTAAACGTATGGCGGAGCGTGGCTATGAAGTGACGGTGACAGATGCGGCAGTT
GATCATATCGGCGAAGCAGGCTTTGACCCACTCTTTGGAGCAAGACCGCTCAAACGTGCAATTCAGCAAGAGCTTGAAAA
CACCTTAGCACAGCAAATTCTCTCAGGCAAATTGTTGCCGAATAGTCCTGTGACAGTGGATTATCGTGAGGGAAGGGTTG
TGGCAGTTCAGTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-846)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-759)

• ATPase family associated with various cellular activities (AAA) (AAA) (201-332)

• AAA lid domain (AAA_lid_9) (340-442)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-67)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (92-143)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	45.029	100	0.46
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.284	100	0.44
clpE	Streptococcus mutans UA159	46.199	79.813	0.369