Detailed information NTG0171632

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AYM36_RS14950
• Genome accession: NZ_CP014441
• Coordinates: 2811733..2812620 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain USA300-SUR23
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2806733..2817620

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AYM36_RS14915 (AYM36_14550)	-	2806752..2806844 (+)	93	WP_010956583.1	hypothetical protein	-
AYM36_RS14920 (AYM36_14555)	-	2806952..2807449 (-)	498	WP_001065268.1	glutathione peroxidase	-
AYM36_RS14925 (AYM36_14560)	-	2807459..2807719 (-)	261	WP_001789910.1	hypothetical protein	-
AYM36_RS14935 (AYM36_14565)	-	2808101..2808214 (-)	114	WP_001791776.1	hypothetical protein	-
AYM36_RS14940 (AYM36_14575)	-	2808873..2810873 (-)	2001	WP_000776751.1	ABC transporter permease	-
AYM36_RS14945 (AYM36_14580)	-	2810870..2811625 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AYM36_RS14950 (AYM36_14585)	braS	2811733..2812620 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AYM36_RS14955 (AYM36_14590)	braR	2812631..2813296 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AYM36_RS14960 (AYM36_14595)	-	2813322..2813522 (-)	201	WP_000604728.1	hypothetical protein	-
AYM36_RS14965 (AYM36_14605)	-	2813720..2815144 (+)	1425	WP_000953744.1	alkaline phosphatase	-
AYM36_RS15835	-	2815214..2815324 (+)	111	WP_001791296.1	hypothetical protein	-
AYM36_RS14975 (AYM36_14610)	-	2815427..2815882 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AYM36_RS14980 (AYM36_14615)	-	2816127..2816888 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=171632 AYM36_RS14950 WP_000143419.1 2811733..2812620(-) (braS) [Staphylococcus aureus strain USA300-SUR23]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=171632 AYM36_RS14950 WP_000143419.1 2811733..2812620(-) (braS) [Staphylococcus aureus strain USA300-SUR23]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997