Detailed information NTG0171627

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AYM36_RS10830
• Genome accession: NZ_CP014441
• Coordinates: 2069257..2070300 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain USA300-SUR23
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2064257..2075300

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AYM36_RS10800 (AYM36_10525)	-	2064675..2065931 (-)	1257	WP_001795438.1	aminopeptidase	-
AYM36_RS10805 (AYM36_10530)	-	2065934..2066134 (-)	201	WP_000180461.1	DUF1128 family protein	-
AYM36_RS10810 (AYM36_10535)	-	2066281..2066745 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AYM36_RS10815 (AYM36_10540)	-	2066752..2067027 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AYM36_RS10820 (AYM36_10545)	-	2067305..2068522 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
AYM36_RS10825 (AYM36_10550)	vraR	2068638..2069267 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
AYM36_RS10830 (AYM36_10555)	vraS	2069257..2070300 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AYM36_RS10835 (AYM36_10560)	liaF	2070297..2070998 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AYM36_RS10840 (AYM36_10565)	-	2071013..2071399 (-)	387	WP_001110179.1	hypothetical protein	-
AYM36_RS10845 (AYM36_10570)	map	2071616..2072374 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AYM36_RS10850 (AYM36_10580)	-	2072902..2073888 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
AYM36_RS10860 (AYM36_10585)	-	2074378..2074791 (-)	414	WP_001549145.1	hypothetical protein	-
AYM36_RS10865 (AYM36_10590)	-	2074820..2074930 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=171627 AYM36_RS10830 WP_001017131.1 2069257..2070300(-) (vraS) [Staphylococcus aureus strain USA300-SUR23]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=171627 AYM36_RS10830 WP_001017131.1 2069257..2070300(-) (vraS) [Staphylococcus aureus strain USA300-SUR23]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1