Detailed information NTG0171548

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AYM34_RS14965
• Genome accession: NZ_CP014435
• Coordinates: 2816020..2816907 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain USA300-SUR21
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2811020..2821907

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AYM34_RS14930 (AYM34_14575)	-	2811039..2811131 (+)	93	WP_010956583.1	hypothetical protein	-
AYM34_RS14935 (AYM34_14580)	-	2811239..2811736 (-)	498	WP_001065268.1	glutathione peroxidase	-
AYM34_RS14940 (AYM34_14585)	-	2811746..2812006 (-)	261	WP_001789910.1	hypothetical protein	-
AYM34_RS14950 (AYM34_14590)	-	2812388..2812501 (-)	114	WP_001791776.1	hypothetical protein	-
AYM34_RS14955 (AYM34_14600)	-	2813160..2815160 (-)	2001	WP_000776751.1	ABC transporter permease	-
AYM34_RS14960 (AYM34_14605)	-	2815157..2815912 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AYM34_RS14965 (AYM34_14610)	braS	2816020..2816907 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AYM34_RS14970 (AYM34_14615)	braR	2816918..2817583 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AYM34_RS14975 (AYM34_14620)	-	2817609..2817809 (-)	201	WP_000604728.1	hypothetical protein	-
AYM34_RS14980 (AYM34_14630)	-	2818007..2819431 (+)	1425	WP_000953744.1	alkaline phosphatase	-
AYM34_RS15865	-	2819501..2819611 (+)	111	WP_001791296.1	hypothetical protein	-
AYM34_RS14990 (AYM34_14635)	-	2819714..2820169 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AYM34_RS14995 (AYM34_14640)	-	2820414..2821175 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=171548 AYM34_RS14965 WP_000143419.1 2816020..2816907(-) (braS) [Staphylococcus aureus strain USA300-SUR21]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=171548 AYM34_RS14965 WP_000143419.1 2816020..2816907(-) (braS) [Staphylococcus aureus strain USA300-SUR21]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997