Detailed information NTG0171464

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AYM32_RS14985
• Genome accession: NZ_CP014429
• Coordinates: 2816128..2817015 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain USA300-SUR19
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2811128..2822015

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AYM32_RS14950 (AYM32_14585)	-	2811147..2811239 (+)	93	WP_010956583.1	hypothetical protein	-
AYM32_RS14955 (AYM32_14590)	-	2811347..2811844 (-)	498	WP_001065268.1	glutathione peroxidase	-
AYM32_RS14960 (AYM32_14595)	-	2811854..2812114 (-)	261	WP_001789910.1	hypothetical protein	-
AYM32_RS14970 (AYM32_14600)	-	2812496..2812609 (-)	114	WP_001791776.1	hypothetical protein	-
AYM32_RS14975 (AYM32_14610)	-	2813268..2815268 (-)	2001	WP_000776751.1	ABC transporter permease	-
AYM32_RS14980 (AYM32_14615)	-	2815265..2816020 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AYM32_RS14985 (AYM32_14620)	braS	2816128..2817015 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AYM32_RS14990 (AYM32_14625)	braR	2817026..2817691 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AYM32_RS14995 (AYM32_14630)	-	2817717..2817917 (-)	201	WP_000604728.1	hypothetical protein	-
AYM32_RS15000 (AYM32_14640)	-	2818115..2819539 (+)	1425	WP_000953744.1	alkaline phosphatase	-
AYM32_RS15875	-	2819609..2819719 (+)	111	WP_001791296.1	hypothetical protein	-
AYM32_RS15010 (AYM32_14645)	-	2819822..2820277 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AYM32_RS15015 (AYM32_14650)	-	2820522..2821283 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=171464 AYM32_RS14985 WP_000143419.1 2816128..2817015(-) (braS) [Staphylococcus aureus strain USA300-SUR19]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=171464 AYM32_RS14985 WP_000143419.1 2816128..2817015(-) (braS) [Staphylococcus aureus strain USA300-SUR19]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997