Detailed information NTG0171292

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AYM28_RS10865
• Genome accession: NZ_CP014415
• Coordinates: 2073777..2074820 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain USA300-SUR15
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2068777..2079820

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AYM28_RS10835 (AYM28_10560)	-	2069195..2070451 (-)	1257	WP_001795438.1	aminopeptidase	-
AYM28_RS10840 (AYM28_10565)	-	2070454..2070654 (-)	201	WP_000180461.1	DUF1128 family protein	-
AYM28_RS10845 (AYM28_10570)	-	2070801..2071265 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AYM28_RS10850 (AYM28_10575)	-	2071272..2071547 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AYM28_RS10855 (AYM28_10580)	-	2071825..2073042 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
AYM28_RS10860 (AYM28_10585)	vraR	2073158..2073787 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
AYM28_RS10865 (AYM28_10590)	vraS	2073777..2074820 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AYM28_RS10870 (AYM28_10595)	liaF	2074817..2075518 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AYM28_RS10875 (AYM28_10600)	-	2075533..2075919 (-)	387	WP_001110179.1	hypothetical protein	-
AYM28_RS10880 (AYM28_10605)	map	2076136..2076894 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AYM28_RS10885 (AYM28_10615)	-	2077422..2078408 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
AYM28_RS10895 (AYM28_10620)	-	2078839..2079252 (-)	414	WP_001549145.1	hypothetical protein	-
AYM28_RS10900 (AYM28_10625)	-	2079281..2079391 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=171292 AYM28_RS10865 WP_001017131.1 2073777..2074820(-) (vraS) [Staphylococcus aureus strain USA300-SUR15]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=171292 AYM28_RS10865 WP_001017131.1 2073777..2074820(-) (vraS) [Staphylococcus aureus strain USA300-SUR15]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1