Detailed information NTG0171171

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AYM25_RS14650
• Genome accession: NZ_CP014407
• Coordinates: 2772625..2773512 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain USA300-SUR12
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2767625..2778512

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AYM25_RS14615 (AYM25_14255)	-	2767644..2767736 (+)	93	WP_010956583.1	hypothetical protein	-
AYM25_RS14620 (AYM25_14260)	-	2767844..2768341 (-)	498	WP_001065268.1	glutathione peroxidase	-
AYM25_RS14625 (AYM25_14265)	-	2768351..2768611 (-)	261	WP_001789910.1	hypothetical protein	-
AYM25_RS14635 (AYM25_14270)	-	2768993..2769106 (-)	114	WP_001791776.1	hypothetical protein	-
AYM25_RS14640 (AYM25_14280)	-	2769765..2771765 (-)	2001	WP_000776751.1	ABC transporter permease	-
AYM25_RS14645 (AYM25_14285)	-	2771762..2772517 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AYM25_RS14650 (AYM25_14290)	braS	2772625..2773512 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AYM25_RS14655 (AYM25_14295)	braR	2773523..2774188 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AYM25_RS14660 (AYM25_14300)	-	2774214..2774414 (-)	201	WP_000604728.1	hypothetical protein	-
AYM25_RS14665 (AYM25_14310)	-	2774612..2776036 (+)	1425	WP_000953744.1	alkaline phosphatase	-
AYM25_RS15515	-	2776106..2776216 (+)	111	WP_001791296.1	hypothetical protein	-
AYM25_RS14675 (AYM25_14315)	-	2776319..2776774 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AYM25_RS14680 (AYM25_14320)	-	2777019..2777780 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=171171 AYM25_RS14650 WP_000143419.1 2772625..2773512(-) (braS) [Staphylococcus aureus strain USA300-SUR12]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=171171 AYM25_RS14650 WP_000143419.1 2772625..2773512(-) (braS) [Staphylococcus aureus strain USA300-SUR12]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997