Detailed information NTG0171130

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AYM24_RS14965
• Genome accession: NZ_CP014402
• Coordinates: 2814298..2815185 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain USA300-SUR11
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2809298..2820185

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AYM24_RS14930 (AYM24_14575)	-	2809317..2809409 (+)	93	WP_010956583.1	hypothetical protein	-
AYM24_RS14935 (AYM24_14580)	-	2809517..2810014 (-)	498	WP_001065268.1	glutathione peroxidase	-
AYM24_RS14940 (AYM24_14585)	-	2810024..2810284 (-)	261	WP_001789910.1	hypothetical protein	-
AYM24_RS14950 (AYM24_14590)	-	2810666..2810779 (-)	114	WP_001791776.1	hypothetical protein	-
AYM24_RS14955 (AYM24_14600)	-	2811438..2813438 (-)	2001	WP_000776751.1	ABC transporter permease	-
AYM24_RS14960 (AYM24_14605)	-	2813435..2814190 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AYM24_RS14965 (AYM24_14610)	braS	2814298..2815185 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AYM24_RS14970 (AYM24_14615)	braR	2815196..2815861 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AYM24_RS14975 (AYM24_14620)	-	2815887..2816087 (-)	201	WP_000604728.1	hypothetical protein	-
AYM24_RS14980 (AYM24_14630)	-	2816285..2817709 (+)	1425	WP_000953744.1	alkaline phosphatase	-
AYM24_RS15870	-	2817779..2817889 (+)	111	WP_001791296.1	hypothetical protein	-
AYM24_RS14990 (AYM24_14635)	-	2817992..2818447 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AYM24_RS14995 (AYM24_14640)	-	2818692..2819453 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=171130 AYM24_RS14965 WP_000143419.1 2814298..2815185(-) (braS) [Staphylococcus aureus strain USA300-SUR11]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=171130 AYM24_RS14965 WP_000143419.1 2814298..2815185(-) (braS) [Staphylococcus aureus strain USA300-SUR11]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997