Detailed information NTG0171083

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AYM23_RS10845
• Genome accession: NZ_CP014397
• Coordinates: 2071874..2072917 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain USA300-SUR10
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2066874..2077917

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AYM23_RS10815 (AYM23_10545)	-	2067292..2068548 (-)	1257	WP_001795438.1	aminopeptidase	-
AYM23_RS10820 (AYM23_10550)	-	2068551..2068751 (-)	201	WP_000180461.1	DUF1128 family protein	-
AYM23_RS10825 (AYM23_10555)	-	2068898..2069362 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AYM23_RS10830 (AYM23_10560)	-	2069369..2069644 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AYM23_RS10835 (AYM23_10565)	-	2069922..2071139 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
AYM23_RS10840 (AYM23_10570)	vraR	2071255..2071884 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
AYM23_RS10845 (AYM23_10575)	vraS	2071874..2072917 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AYM23_RS10850 (AYM23_10580)	liaF	2072914..2073615 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AYM23_RS10855 (AYM23_10585)	-	2073630..2074016 (-)	387	WP_001110179.1	hypothetical protein	-
AYM23_RS10860 (AYM23_10590)	map	2074233..2074991 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AYM23_RS10865 (AYM23_10600)	-	2075519..2076505 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
AYM23_RS10875 (AYM23_10605)	-	2076936..2077349 (-)	414	WP_001549145.1	hypothetical protein	-
AYM23_RS10880 (AYM23_10610)	-	2077378..2077488 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=171083 AYM23_RS10845 WP_001017131.1 2071874..2072917(-) (vraS) [Staphylococcus aureus strain USA300-SUR10]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=171083 AYM23_RS10845 WP_001017131.1 2071874..2072917(-) (vraS) [Staphylococcus aureus strain USA300-SUR10]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1