Detailed information NTG0170921

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AYM19_RS14970
• Genome accession: NZ_CP014381
• Coordinates: 2816019..2816906 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain USA300-SUR6
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2811019..2821906

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AYM19_RS14935 (AYM19_14575)	-	2811038..2811130 (+)	93	WP_010956583.1	hypothetical protein	-
AYM19_RS14940 (AYM19_14580)	-	2811238..2811735 (-)	498	WP_001065268.1	glutathione peroxidase	-
AYM19_RS14945 (AYM19_14585)	-	2811745..2812005 (-)	261	WP_001789910.1	hypothetical protein	-
AYM19_RS14955 (AYM19_14590)	-	2812387..2812500 (-)	114	WP_001791776.1	hypothetical protein	-
AYM19_RS14960 (AYM19_14600)	-	2813159..2815159 (-)	2001	WP_000776751.1	ABC transporter permease	-
AYM19_RS14965 (AYM19_14605)	-	2815156..2815911 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AYM19_RS14970 (AYM19_14610)	braS	2816019..2816906 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AYM19_RS14975 (AYM19_14615)	braR	2816917..2817582 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AYM19_RS14980 (AYM19_14620)	-	2817608..2817808 (-)	201	WP_000604728.1	hypothetical protein	-
AYM19_RS14985 (AYM19_14630)	-	2818006..2819430 (+)	1425	WP_000953744.1	alkaline phosphatase	-
AYM19_RS15685	-	2819500..2819610 (+)	111	WP_001791296.1	hypothetical protein	-
AYM19_RS14995 (AYM19_14635)	-	2819713..2820168 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AYM19_RS15000 (AYM19_14640)	-	2820413..2821174 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=170921 AYM19_RS14970 WP_000143419.1 2816019..2816906(-) (braS) [Staphylococcus aureus strain USA300-SUR6]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=170921 AYM19_RS14970 WP_000143419.1 2816019..2816906(-) (braS) [Staphylococcus aureus strain USA300-SUR6]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997