Detailed information NTG0170729

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AB466_RS04540
• Genome accession: NZ_CP017677
• Coordinates: 903768..906377 (+)
• Length: 869 a.a.
• NCBI ID: WP_000353954.1
• Uniprot ID: Q99VB5
• Organism: Staphylococcus aureus strain CFSAN007894
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 898768..911377

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB466_RS04525 (AB466_04400)	-	899957..900781 (-)	825	WP_001182436.1	Cof-type HAD-IIB family hydrolase	-
AB466_RS04530 (AB466_04405)	-	900895..901203 (+)	309	WP_000390575.1	metal-sulfur cluster assembly factor	-
AB466_RS04535 (AB466_04410)	-	901751..903565 (+)	1815	WP_001044230.1	acyltransferase family protein	-
AB466_RS04540 (AB466_04415)	clpC	903768..906377 (+)	2610	WP_000353954.1	ATP-dependent chaperone ClpB	Regulator
AB466_RS04545 (AB466_04420)	-	906436..907305 (-)	870	WP_001047069.1	LysR family transcriptional regulator	-
AB466_RS04550 (AB466_04425)	-	907415..908560 (+)	1146	WP_000619360.1	LeuA family protein	-
AB466_RS04555 (AB466_04430)	-	908544..909185 (+)	642	WP_000404422.1	L-threonylcarbamoyladenylate synthase	-
AB466_RS04560 (AB466_04435)	-	909178..910299 (+)	1122	WP_001037440.1	MFS transporter	-
AB466_RS04565 (AB466_04440)	-	910277..910792 (+)	516	WP_000700882.1	YbhB/YbcL family Raf kinase inhibitor-like protein	-

Sequence

Protein

• Length: 869 a.a.
• Molecular weight: 98330.47 Da
• Isoelectric Point: 4.6833

>NTDB_id=170729 AB466_RS04540 WP_000353954.1 903768..906377(+) (clpC) [Staphylococcus aureus strain CFSAN007894]
MDINKMTYAVQSALQQAVELSQQHKLQNIEIEAILSAALNESESLYKSILERANIEVDQLNKAYEDKLNTYASVEGDNIQ
YGQYISQQANQLITKAESYMKEYEDEYISMEHILRSAMDIDQTTKHYINNKVEVIKEIIKKVRGGNHVTSQNPEVNYEAL
AKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPESLLDKTVFELD
LSALVAGAKYRGEFEERLKAVLKEVKESDGRIILFIDEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYRE
YIEKDSALERRFQKVAVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDLVDQACATI
RTEMGSNPTELDQVNRRVMQLEIEESALKNESDNASKQRLQELQEELANEKEKQAALQSRVESEKEKIANLQEKRAQLDE
SRQALEDAQTNNNLEKAAELQYGTIPQLEKELRELEDNFQDEQGEDTDRMIREVVTDEEIGDIVSQWTGIPVSKLVETER
EKLLHLSDILHKRVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLAASLFDSEKHMIRIDMSE
YMEKHAVSRLIGAPPGYIGHDEGGQLTEAVRRNPYSVILLDEVEKAHTDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIM
TSNIGSQVLLENVKETGEITESTEKAVMTNLNAYFKPEILNRMDDIVLFKPLSIDDMSMIVDKILTQLNIRLLEQRISIE
VSDDAKAWLGQEAYEPQYGARPLKRFVQRQIETPLARMMIKEGFPEGTTIKVNLNSDNNLTFNVEKIHE

Nucleotide

• Length: 2610 bp

>NTDB_id=170729 AB466_RS04540 WP_000353954.1 903768..906377(+) (clpC) [Staphylococcus aureus strain CFSAN007894]
ATGGATATAAATAAAATGACATATGCTGTTCAAAGTGCTTTACAACAAGCAGTTGAACTGAGTCAGCAACATAAATTACA
AAATATAGAAATTGAGGCAATTTTAAGCGCTGCCTTAAATGAAAGTGAAAGCTTATATAAAAGTATTTTAGAACGAGCAA
ATATTGAGGTAGATCAATTAAACAAAGCTTATGAAGACAAACTAAACACGTATGCATCTGTAGAAGGTGACAATATACAA
TATGGTCAATATATTAGCCAACAAGCAAACCAATTGATAACTAAGGCTGAATCATACATGAAAGAATATGAAGATGAATA
TATTTCAATGGAGCATATTTTACGTTCGGCAATGGACATTGATCAAACAACAAAACATTATATAAATAATAAAGTAGAAG
TTATCAAAGAAATTATTAAAAAAGTAAGAGGGGGAAATCACGTGACATCACAAAATCCAGAAGTTAATTACGAAGCATTA
GCTAAATATGGCCGCGACTTAGTAGAAGAAGTTAGACAAGGTAAAATGGATCCTGTTATAGGAAGAGATGAAGAAATTCG
AAATACGATTCGTATTTTAAGTCGTAAAACTAAAAACAACCCTGTGCTCATTGGTGAACCAGGTGTTGGTAAAACTGCAA
TTGTTGAAGGATTAGCGCAACGTATAGTTAAGAAAGATGTGCCAGAATCATTATTAGATAAAACTGTTTTTGAGTTAGAT
TTAAGCGCATTAGTAGCGGGCGCTAAATATCGTGGTGAATTTGAAGAGAGATTAAAAGCAGTCCTAAAAGAAGTTAAAGA
GTCTGATGGTAGAATTATATTATTTATTGATGAAATCCATATGCTTGTAGGTGCTGGTAAAACAGATGGTGCCATGGATG
CAGGCAACATGCTAAAACCAATGTTAGCACGAGGAGAGTTACATTGTATTGGTGCAACAACTTTAAATGAATATCGAGAA
TATATTGAAAAAGATTCGGCATTAGAGCGTCGTTTCCAAAAAGTAGCAGTTAGTGAGCCTGATGTTGAAGATACAATTTC
AATTTTACGTGGTTTAAAAGAACGATATGAAGTGTATCATGGTGTGCGTATTCAAGATAGAGCCTTAGTTGCTGCCGCTG
AATTGTCTGATCGTTACATCACTGATCGTTTTTTACCAGATAAAGCGATTGATTTAGTTGACCAAGCATGTGCAACAATT
CGTACGGAAATGGGATCAAATCCAACTGAATTGGATCAAGTTAATAGACGTGTCATGCAATTAGAAATTGAAGAAAGCGC
ACTTAAAAATGAATCTGACAATGCGAGCAAACAGAGATTACAAGAACTACAAGAAGAGCTTGCCAATGAAAAAGAGAAAC
AAGCAGCACTTCAATCTCGTGTAGAATCAGAAAAAGAAAAAATAGCAAATTTACAAGAAAAACGTGCGCAACTAGATGAA
AGTAGACAAGCGTTGGAAGATGCACAAACAAATAACAATTTAGAAAAAGCTGCTGAACTACAATATGGAACAATTCCTCA
ATTGGAAAAAGAACTTAGAGAATTAGAGGATAATTTCCAAGATGAGCAAGGTGAAGATACAGATCGAATGATTCGTGAAG
TTGTAACAGACGAAGAAATTGGCGATATTGTCAGCCAATGGACAGGCATACCAGTTTCAAAATTAGTTGAAACAGAACGT
GAAAAATTACTTCACTTAAGTGACATCTTGCATAAACGTGTTGTAGGTCAAGATAAAGCGGTTGACCTGGTTTCAGATGC
AGTAGTTAGAGCAAGAGCAGGTATTAAAGATCCAAACAGACCTATTGGTAGTTTCTTATTCCTAGGTCCAACTGGAGTAG
GTAAAACTGAATTAGCTAAATCATTAGCTGCATCATTATTTGATTCTGAAAAACATATGATTCGTATTGATATGAGTGAA
TATATGGAAAAACATGCAGTATCAAGATTGATAGGGGCACCTCCAGGATATATTGGACATGATGAAGGGGGTCAATTAAC
TGAAGCGGTTCGTCGTAATCCATACTCAGTTATCTTATTAGATGAGGTTGAAAAAGCGCATACTGACGTCTTTAATGTAT
TATTGCAAATTTTAGATGAAGGCCGTTTAACTGATTCTAAAGGACGTAGCGTTGATTTTAAAAATACTATTATTATTATG
ACAAGTAATATTGGATCTCAAGTTTTATTAGAAAACGTAAAAGAGACTGGTGAAATTACAGAATCAACAGAAAAAGCTGT
TATGACAAATTTAAATGCATATTTCAAACCAGAAATTTTGAATCGTATGGATGACATCGTATTATTTAAACCTCTATCTA
TTGATGACATGAGTATGATTGTAGACAAAATATTAACGCAATTAAATATAAGATTATTAGAACAGCGAATCTCAATTGAA
GTTTCTGATGATGCTAAAGCTTGGCTAGGTCAAGAAGCTTATGAACCTCAATACGGTGCAAGACCATTAAAACGTTTTGT
ACAACGCCAAATTGAAACACCATTAGCACGTATGATGATTAAAGAGGGATTCCCAGAAGGTACAACGATTAAAGTTAATT
TAAATTCAGACAATAACTTAACGTTTAATGTTGAAAAAATTCATGAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-443)

• AAA domain (Cdc48 subfamily) (AAA_2) (600-766)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-121)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-66)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (772-852)

• ATPase family associated with various cellular activities (AAA) (AAA) (202-334)

3D structure

• AlphaFold DB: Q99VB5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	44.289	98.734	0.437
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	39.863	100	0.403