Detailed information NTG0170638

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: BKN48_RS10640
• Genome accession: NZ_CP017676
• Coordinates: 2015450..2016532 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain VV2
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2010450..2021532

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BKN48_RS10625 (BKN48_10625)	mcsB	2010458..2011549 (+)	1092	WP_021482008.1	protein arginine kinase	-
BKN48_RS10630 (BKN48_10630)	clpC	2011546..2013978 (+)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
BKN48_RS10635 (BKN48_10635)	radA/sms	2014070..2015446 (+)	1377	WP_070548367.1	DNA repair protein RadA	Machinery gene
BKN48_RS10640 (BKN48_10640)	disA	2015450..2016532 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
BKN48_RS10645 (BKN48_10645)	yacL	2016648..2017748 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
BKN48_RS10650 (BKN48_10650)	ispD	2017763..2018461 (+)	699	WP_032726598.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
BKN48_RS10655 (BKN48_10655)	ispF	2018454..2018930 (+)	477	WP_070548369.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
BKN48_RS10660 (BKN48_10660)	gltX	2019021..2020472 (+)	1452	WP_014478617.1	glutamate--tRNA ligase	-
BKN48_RS10670 (BKN48_10670)	cysE	2020774..2021427 (+)	654	WP_003225749.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=170638 BKN48_RS10640 WP_003225736.1 2015450..2016532(+) (disA) [Bacillus subtilis strain VV2]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=170638 BKN48_RS10640 WP_003225736.1 2015450..2016532(+) (disA) [Bacillus subtilis strain VV2]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGCATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAGTATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAGAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1