Detailed information NTG0170476

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: BKM67_RS10445
• Genome accession: NZ_CP017667
• Coordinates: 2144427..2146967 (-)
• Length: 846 a.a.
• NCBI ID: WP_105183971.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 1081
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2139427..2151967

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BKM67_RS10415 (BKM67_10165)	-	2140585..2141328 (-)	744	WP_013730659.1	amino acid ABC transporter ATP-binding protein	-
BKM67_RS10420 (BKM67_10170)	-	2141328..2142131 (-)	804	WP_105183969.1	amino acid ABC transporter permease	-
BKM67_RS10425 (BKM67_10175)	-	2142317..2143168 (-)	852	WP_105183970.1	amino acid ABC transporter substrate-binding protein	-
BKM67_RS10430 (BKM67_10180)	-	2143201..2143887 (-)	687	WP_014638811.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
BKM67_RS10975 (BKM67_10185)	-	2144001..2144174 (-)	174	WP_044674643.1	hypothetical protein	-
BKM67_RS11190	-	2144208..2144330 (-)	123	WP_323146728.1	DUF3021 family protein	-
BKM67_RS10445 (BKM67_10190)	hexA	2144427..2146967 (-)	2541	WP_105183971.1	DNA mismatch repair protein MutS	Machinery gene
BKM67_RS10450 (BKM67_10195)	argR	2146982..2147422 (-)	441	WP_002937036.1	arginine repressor	-
BKM67_RS10455 (BKM67_10200)	argS	2147529..2149217 (+)	1689	WP_014736566.1	arginine--tRNA ligase	-
BKM67_RS10460 (BKM67_10205)	-	2149396..2150310 (+)	915	WP_105183972.1	SH3 domain-containing protein	-
BKM67_RS10465 (BKM67_10210)	-	2150364..2150885 (-)	522	WP_012775401.1	hypothetical protein	-
BKM67_RS10470 (BKM67_10215)	-	2151014..2151196 (+)	183	WP_014638816.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95156.62 Da
• Isoelectric Point: 4.8252

>NTDB_id=170476 BKM67_RS10445 WP_105183971.1 2144427..2146967(-) (hexA) [Streptococcus suis strain 1081]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILLQINEPALGNLVAGLDPIPELHALINSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELAKIEGQMLEARDRSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPTHPAPSVV
EEPSGQIDLFADTPSHPVLDELEKLDIYNMTPMEVMMAVAELKKKI

Nucleotide

• Length: 2541 bp

>NTDB_id=170476 BKM67_RS10445 WP_105183971.1 2144427..2146967(-) (hexA) [Streptococcus suis strain 1081]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAGTTATTTTATGAAGATGCGGTAGAAGCGGCACAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAAAATCCGATTCCTATGGCGGGGGTACCGTATCACGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
ACAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAAATCCGCAATTTACGGGCACGTGAATTGGTCATCGGCTACGCTTTATCTGAGGAAGAAGAGCAGGTCTT
TTCGAATCAGATGAACCTCCTGCTCTCTTTTGAAGATGAGGTGACAGAGGATGTCCAATTGATTGATAACTCCTTGACAG
ACTTGGAAAAGGCTGCGGCAGGTAAACTCCTCAGCTACCTACATCGGACTCAGATGCGAGATCTGAGCCACTTGCAAAAG
GTGGTCCACTATGAAATCAAGGACTATCTGCAAATGGACTATGCAACCAAGTCCAGTCTGGATCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGCTAGACGAAACTAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGATCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTCGAGGCTTTAAAAGGTGTCTATGACATCGAACGCTTGGCCAGCCGGGTGTCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCCCAGACTCTGGGAAATATCCCAGCAATCAAGAATATCTTGCTACAAATCAATG
AGCCTGCTCTAGGTAATCTGGTGGCTGGATTGGACCCAATCCCAGAACTGCACGCTCTCATCAACTCTGCTATTGACCCA
GAAGCCCAAGGGACCATCACAGATGGAAACATCATCCGTACAGGCTTTGACGAAACGCTGGATCAGTATCGTCTGGTCAT
GCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCTAAGGAGCGTGAAGCATCTGGTATCAACAATCTTAAGATTGATT
ACAATAAAAAAGACGGTTACTATTTCCATGTGACCAATTCCAATCTGGGCAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAACGTTATGGAACGGAAGAGTTGGCTAAGATCGAAGGGCAGATGTTGGAGGCGCGTGATAGGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATCGGTCGCTTGCAGAAGTTGGCTC
GAACTATTGCAACCATTGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTTACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACTTGAATACCGATACACATATGCAACTGATTACTGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGAC
AGTTGGCGGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACCCGAATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTCATGGTCGAAATGATGGAGGCCAATAA
GGCGGTCCGTCTGGCGACAGATCGGTCGCTCATCCTCTTTGATGAGTTGGGACGGGGAACGGCCACCTATGACGGTATGG
CCCTGGCCCAGTCTATCATCGAGTACATCCACGACAAGATTGGAGCCAAGACTCTCTTTGCCACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACTTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGCCAAGTCACCTTCCT
CCACAAGATTGCACAAGGCCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAACTAT
TGCAGCGGGCGGACAGGATTTTGCAGACACTTGAAAACCAAGCCCCTACTGCACCAACTCACCCAGCTCCGTCAGTAGTG
GAAGAGCCGTCTGGTCAAATCGACCTCTTCGCAGACACGCCTTCTCACCCAGTACTTGATGAACTGGAAAAACTAGACAT
CTACAATATGACCCCTATGGAAGTCATGATGGCAGTGGCGGAGTTGAAGAAAAAAATATAA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-506)

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.759	100	0.738
mutS	Pseudomonas stutzeri strain ATCC 17587	37.762	100	0.383