Detailed information NTG0169869

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: AXF37_RS09625
• Genome accession: NZ_CP014257
• Coordinates: 2129747..2132479 (+)
• Length: 910 a.a.
• NCBI ID: WP_080453263.1
• Uniprot ID: -
• Organism: Legionella pneumophila subsp. pascullei strain D-7119
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2124747..2137479

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AXF37_RS09605 (AXF37_09600)	gstA	2124892..2125497 (-)	606	WP_027222087.1	glutathione transferase GstA	-
AXF37_RS09610 (AXF37_09605)	-	2125692..2126687 (-)	996	WP_027222088.1	hypothetical protein	-
AXF37_RS09615 (AXF37_09610)	-	2126728..2127990 (-)	1263	WP_027222089.1	serine hydrolase domain-containing protein	-
AXF37_RS09620 (AXF37_09615)	gltX	2128236..2129648 (-)	1413	WP_027222090.1	glutamate--tRNA ligase	-
AXF37_RS09625 (AXF37_09620)	letS	2129747..2132479 (+)	2733	WP_080453263.1	two-component system sensor histidine kinase LetS	Regulator
AXF37_RS09630 (AXF37_09625)	-	2132577..2133821 (+)	1245	WP_027222092.1	6-phosphofructokinase	-
AXF37_RS09635 (AXF37_09630)	pilA2	2133818..2134231 (-)	414	WP_027222093.1	pilin	Machinery gene
AXF37_RS09640 (AXF37_09635)	pilA2	2134427..2134837 (-)	411	WP_011214168.1	pilin	Machinery gene
AXF37_RS09645 (AXF37_09640)	-	2135139..2135456 (+)	318	WP_027222094.1	BolA family protein	-
AXF37_RS09650 (AXF37_09645)	-	2135531..2136952 (+)	1422	WP_027222095.1	APC family permease	-

Sequence

Protein

• Length: 910 a.a.
• Molecular weight: 103061.50 Da
• Isoelectric Point: 7.5215

>NTDB_id=169869 AXF37_RS09625 WP_080453263.1 2129747..2132479(+) (letS) [Legionella pneumophila subsp. pascullei strain D-7119]
MLKSIGIKYQLRITTLIPAFLVALLFAFFYNGLFGKDLKQHMSRLGEAYIRQLLPAAQYAMLRNDYRTLQGLINASTINP
EVKALAFYNADGRLIAYRGGKHSIHKPFNPPDYTGDYIESKQINPFTINFIAPITIPKFNLYSSTEFKEPSTPKVFQADD
ILGWLSIDIDTQSLLIKRYQMLIVTIFITLFGLLMGLTIHYFLSKRIYMPIARLRRSMKQILSNEFETEIRVSSPGELGI
IEKGCAHLQRQYLNTVRDLNHHIEIATADLQQSLELLEEKNIELSLEKKKTEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKSSAQDLLSIINDILDFSKIDAGKLNLDCIPLDIRGCIDEVLSLASPNAHKKGIDLIPITD
INVPKMVLGDPLRIKQIISNLVTNAVKFTDHGYVLIRTKIEQETDKDYTLLFAITDTGIGISPEDQTKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMHGRISLTSEINKGSTFSARIKVEKLVAYEIEKNQTHRFAHLKIICFDDNPLHLEAMGNG
LGFWGIEAIRVDSFNKLSRTLTKHKDCKIAFINVNQGCERQAAELIAKHKQIPFVLISKWPINDFAALGARGFLYKPISI
QKLQDLIESIANENQTEKNTNQELDTLREQLRFLHPELLIAEDNPVNKMLLTSLLNNNANITTVDDGEMAFTACEDKKFD
MILLDLQMPKLNGLEAAKMIRQKSLMNKHSPIVLITASSSDLSSIDMKKSGVDYCFQKPIDEKQLLIQILRIVDKTKHAA
IDWQLCVQKVSGNQALAEEFLAKFIEELYKNREEFIELMHQKNVKGLADLAHKLHGACCFCGVPILQKRVAQLEKLARRT
ANADNLTEAFTDLIQSIDAVISEYENQYSQ

Nucleotide

• Length: 2733 bp

>NTDB_id=169869 AXF37_RS09625 WP_080453263.1 2129747..2132479(+) (letS) [Legionella pneumophila subsp. pascullei strain D-7119]
ATGTTGAAAAGTATTGGTATTAAGTATCAGCTAAGAATCACTACTCTTATTCCTGCCTTTTTAGTTGCCTTGCTTTTTGC
CTTTTTTTATAACGGTCTATTTGGTAAAGATCTAAAGCAGCATATGTCCAGACTGGGTGAAGCCTACATTAGACAATTAC
TCCCAGCCGCCCAGTATGCCATGCTTCGCAATGATTATCGTACATTACAGGGTTTAATCAATGCCTCAACCATTAATCCA
GAGGTAAAGGCTTTGGCATTTTATAATGCCGATGGTCGATTAATTGCTTATCGTGGTGGCAAGCACTCTATTCATAAACC
CTTCAATCCGCCTGACTATACCGGTGACTACATTGAAAGTAAGCAAATTAATCCATTCACCATTAATTTTATAGCGCCGA
TTACTATCCCAAAGTTCAATTTGTACTCCAGTACAGAATTCAAAGAGCCTTCTACGCCTAAAGTATTTCAAGCCGACGAT
ATATTAGGCTGGCTATCTATTGACATTGATACACAATCACTCCTTATAAAACGCTATCAAATGCTTATTGTTACCATTTT
TATTACTCTCTTCGGTTTACTCATGGGTTTAACAATTCATTACTTCTTGTCTAAACGAATTTACATGCCTATTGCTCGAT
TGCGTAGAAGTATGAAACAAATTTTAAGTAATGAATTTGAAACAGAAATTCGTGTTTCAAGTCCAGGAGAATTAGGAATA
ATTGAAAAAGGTTGCGCTCATTTGCAACGACAATATTTAAATACGGTTCGCGATCTGAATCACCATATTGAAATCGCTAC
CGCAGATCTGCAACAAAGTCTCGAACTTCTGGAAGAAAAAAACATTGAGCTATCACTGGAGAAGAAAAAAACTGAAGAAA
AAAGCCGGCAAAAATCAGAATTTATTGCCAACATGAGTCATGAAATACGTACACCAATGAATGGAGTGATTGGTTTTACC
AATGTTTTATTGGAAAGCAAGCTGGATCCTTTACAACTGGACTACGTTAAAACAATCAAATCATCAGCGCAGGATTTGTT
AAGTATCATCAATGATATTCTGGATTTTTCTAAAATTGATGCGGGCAAATTAAATCTCGATTGCATCCCGCTAGACATAA
GAGGCTGCATTGATGAGGTTTTATCCCTGGCAAGCCCCAATGCGCACAAAAAAGGAATAGATTTAATCCCGATTACAGAC
ATTAATGTGCCCAAAATGGTATTGGGTGACCCTTTAAGAATCAAGCAAATCATCAGTAATCTGGTGACCAATGCAGTAAA
ATTTACAGACCATGGATACGTTCTTATACGCACTAAAATAGAGCAAGAAACAGATAAAGATTATACCTTGCTATTTGCCA
TTACGGATACGGGAATAGGTATTTCACCAGAGGATCAAACGAAACTGTTTACTGCCTTCAATCAGGCAGATACCAGCATC
ACACGCCGTTACGGTGGATCAGGATTGGGCTTGGTGATATGTAAAAAATTATGTGAAGAAATGCATGGGCGCATTAGTCT
AACCAGTGAAATAAACAAAGGCTCTACTTTTAGCGCACGCATTAAAGTTGAAAAACTTGTTGCTTATGAGATTGAAAAAA
ATCAAACTCATCGTTTCGCCCATTTAAAAATCATTTGCTTTGATGACAATCCTCTCCATTTGGAAGCAATGGGTAATGGC
TTGGGCTTTTGGGGTATAGAAGCTATACGCGTTGATTCATTTAATAAACTTTCCCGAACATTGACAAAACATAAAGATTG
CAAAATTGCCTTTATTAATGTCAATCAAGGATGTGAGCGTCAAGCCGCTGAACTCATTGCCAAACATAAGCAAATTCCTT
TCGTATTAATTTCCAAATGGCCTATCAATGATTTTGCGGCGCTAGGTGCTCGAGGATTTCTTTACAAACCTATCAGCATC
CAAAAGCTTCAGGATTTGATTGAATCGATAGCTAATGAAAACCAAACTGAGAAAAATACTAACCAGGAACTGGATACTTT
ACGCGAACAACTTCGCTTTCTTCATCCAGAGCTACTGATTGCAGAAGACAACCCAGTCAATAAAATGCTATTAACATCCC
TATTAAACAATAATGCCAATATAACAACGGTTGATGATGGCGAAATGGCCTTTACTGCTTGTGAGGATAAAAAATTTGAC
ATGATTTTACTGGATCTGCAAATGCCAAAACTTAATGGTTTGGAAGCAGCCAAAATGATACGCCAAAAATCCCTAATGAA
TAAACACTCTCCTATCGTTCTCATTACCGCCAGTAGCAGTGATCTGAGCTCCATCGATATGAAAAAATCTGGAGTTGATT
ATTGTTTTCAAAAACCTATAGATGAAAAACAATTGTTAATCCAAATTCTTCGCATCGTTGATAAAACCAAACATGCTGCC
ATCGATTGGCAATTATGTGTTCAGAAAGTTTCAGGTAATCAAGCGCTTGCTGAAGAGTTCCTCGCCAAATTTATAGAAGA
ATTATATAAGAATCGTGAAGAATTTATTGAGTTAATGCATCAAAAAAACGTAAAGGGTCTGGCTGATTTGGCTCATAAAT
TACATGGCGCCTGTTGTTTTTGTGGTGTGCCTATTTTACAAAAGAGAGTAGCTCAATTAGAGAAACTTGCAAGACGAACA
GCTAATGCTGATAATTTAACCGAAGCCTTTACTGATTTAATACAAAGTATTGATGCAGTGATTAGTGAATATGAAAATCA
GTATTCGCAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Response regulator receiver domain (Response_reg) (679-787)

• Single cache domain 4 (sCache_4) (36-180)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

• Hpt domain (Hpt) (819-899)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	98.901	100	0.989