Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   AWM75_RS06370 Genome accession   NZ_CP014163
Coordinates   1378266..1380056 (+) Length   596 a.a.
NCBI ID   WP_067979758.1    Uniprot ID   A0A0X8FLR5
Organism   Aerococcus urinaehominis strain CCUG42038B     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1373266..1385056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AWM75_RS06345 (AWM75_06345) - 1373501..1374520 (+) 1020 WP_067979742.1 lipoyl protein ligase domain-containing protein -
  AWM75_RS06350 (AWM75_06350) - 1374808..1375449 (-) 642 WP_067979746.1 adaptor protein MecA -
  AWM75_RS06355 (AWM75_06355) spxA 1375600..1375995 (-) 396 WP_067979749.1 transcriptional regulator SpxA -
  AWM75_RS06360 (AWM75_06360) trpS 1376170..1377168 (+) 999 WP_067979752.1 tryptophan--tRNA ligase -
  AWM75_RS06365 (AWM75_06365) - 1377216..1378214 (+) 999 WP_067979755.1 competence protein CoiA -
  AWM75_RS06370 (AWM75_06370) pepF 1378266..1380056 (+) 1791 WP_067979758.1 oligoendopeptidase F Regulator
  AWM75_RS06375 (AWM75_06375) - 1380135..1380842 (-) 708 WP_067979760.1 DsbA family protein -
  AWM75_RS06380 (AWM75_06380) - 1380880..1381458 (-) 579 WP_067979763.1 CYTH domain-containing protein -
  AWM75_RS06385 (AWM75_06385) - 1381609..1382235 (+) 627 WP_067980912.1 GTP pyrophosphokinase -
  AWM75_RS06390 (AWM75_06390) - 1382248..1383078 (+) 831 WP_067979766.1 NAD kinase -
  AWM75_RS06395 (AWM75_06395) - 1383068..1383955 (+) 888 WP_200778304.1 RluA family pseudouridine synthase -

Sequence

Protein


Download         Length: 596 a.a.        Molecular weight: 67696.50 Da        Isoelectric Point: 4.5020

>NTDB_id=169052 AWM75_RS06370 WP_067979758.1 1378266..1380056(+) (pepF) [Aerococcus urinaehominis strain CCUG42038B]
MTIKEAKPRSQTPEADTWDLTSIYQDDDQARQEMANLADLLADFQGYQGQLSQGKDQVLAALADLAKLSRQLEKVYVYAH
LKHDQDTTNEDYLQLDASAQSLAAQVAEQLAWFTPELLALDQDLLNDLAQVPGYEHYFDTLLRQKNHILPADQEALLAGA
SEIFNNPSQTFSMLNNADLKFGSVTIDGRPVDLTHGSYGVMLESKDREVRRTAFNQLYQHYDQVKYTLAATMSGNIKSHN
YLAKVYGFASARERALFQNNIPLAVYDELVATVNDNLHLLHDFVAYRKDQLGLDEVEMYDMYTPLAGQAPLKYSFEEAKE
VVLAALAPLGDQYINDLKQAFDQRWIDVYENIGKRSGAYSSGAYDTNPYILLNWQDSLNDLYTLVHELGHSMHSYYTRKN
QDYIYGDYSIFVAEVASTTNENLLTEYLLNTVKDKDAQIYILNHYLDGVKGTVFRQTQFAEFEQFMHESEAKGQALTADY
LTNHYESLNRKYYGPSLSNDETIGLEWARIPHFYMNYYVYQYATGFCAATALAERILGEDGSAVNDYLAFLAAGSSDYPI
KVMQQAGVDMTNPNYIQATMNKFEARFSQLRTLLAK

Nucleotide


Download         Length: 1791 bp        

>NTDB_id=169052 AWM75_RS06370 WP_067979758.1 1378266..1380056(+) (pepF) [Aerococcus urinaehominis strain CCUG42038B]
ATGACGATTAAAGAAGCCAAGCCGAGATCACAAACCCCAGAAGCTGATACCTGGGATTTAACTAGTATCTATCAGGATGA
TGACCAAGCTAGGCAAGAGATGGCGAATTTAGCTGATTTATTAGCTGATTTTCAAGGCTATCAAGGCCAATTGAGCCAGG
GCAAAGATCAGGTACTAGCTGCTTTAGCTGATCTAGCAAAGCTGAGCCGCCAACTAGAAAAAGTTTACGTCTATGCCCAT
TTAAAGCATGATCAAGACACAACTAATGAAGATTATTTACAGTTAGACGCTAGTGCCCAGAGTCTAGCTGCCCAGGTGGC
TGAGCAATTAGCTTGGTTTACACCTGAATTACTGGCCTTAGACCAAGACCTCTTAAATGACCTTGCTCAAGTACCGGGCT
ATGAGCATTATTTTGATACTTTATTGAGACAAAAGAATCATATTTTGCCGGCTGACCAAGAGGCGCTCTTGGCTGGGGCT
AGTGAGATTTTTAATAATCCTAGTCAAACTTTTTCTATGCTAAATAATGCCGACCTTAAATTTGGTAGTGTTACCATTGA
TGGTCGTCCAGTTGACCTAACACATGGTAGCTATGGTGTGATGCTGGAAAGTAAAGATCGAGAGGTTAGACGAACTGCTT
TTAACCAACTCTATCAGCACTATGACCAAGTGAAGTACACCTTAGCAGCTACAATGTCAGGTAATATAAAGAGTCATAAC
TATCTGGCTAAAGTATATGGATTTGCTAGTGCACGTGAGCGTGCGCTCTTTCAGAATAATATTCCCTTGGCTGTATATGA
TGAGTTGGTCGCAACTGTTAATGACAATCTTCATCTTTTACACGACTTTGTTGCTTATCGCAAAGATCAATTAGGCCTAG
ATGAGGTTGAAATGTATGATATGTATACGCCTCTAGCTGGCCAAGCTCCTTTGAAATATAGTTTTGAAGAAGCAAAAGAG
GTAGTCTTGGCAGCTCTAGCACCTTTGGGGGACCAATATATTAACGATCTTAAGCAGGCTTTTGACCAGCGTTGGATAGA
TGTATATGAAAATATTGGCAAACGCTCAGGTGCTTATTCATCTGGTGCTTATGATACTAATCCCTATATCTTACTTAATT
GGCAAGATTCCTTAAATGATCTTTACACCTTGGTCCATGAATTAGGGCATTCAATGCATTCTTACTATACGCGTAAAAAT
CAAGACTATATTTATGGCGATTACTCAATATTTGTGGCTGAAGTTGCTTCAACAACTAATGAAAATCTACTAACTGAGTA
CTTGCTAAATACTGTTAAGGATAAGGATGCCCAGATTTATATTCTGAATCATTACTTGGATGGTGTGAAGGGCACAGTCT
TCAGACAGACTCAATTTGCTGAATTTGAACAGTTTATGCATGAGAGTGAAGCTAAGGGTCAAGCGCTAACGGCTGACTAT
CTAACTAATCATTATGAGTCCTTAAATCGTAAGTACTATGGTCCTTCCTTATCAAATGATGAAACAATTGGCTTAGAGTG
GGCCCGGATTCCGCATTTCTACATGAATTATTATGTCTACCAATATGCGACAGGTTTCTGCGCAGCCACCGCTTTAGCTG
AACGAATTCTAGGTGAAGATGGAAGTGCCGTCAATGATTATTTAGCCTTTTTAGCAGCTGGTTCTAGCGATTATCCGATT
AAGGTCATGCAACAAGCCGGCGTTGATATGACTAATCCAAACTATATTCAAGCTACCATGAATAAGTTTGAAGCACGCTT
TAGCCAGTTAAGGACTTTACTGGCAAAATAG

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(116-181)

Peptidase family M3 (Peptidase_M3)

(200-581)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0X8FLR5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

49.916

99.497

0.497

Multiple sequence alignment