Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   A4C39_RS26730 Genome accession   NZ_CP017444
Coordinates   5231038..5232063 (+) Length   341 a.a.
NCBI ID   WP_000644904.1    Uniprot ID   P0ACN8
Organism   Escherichia coli O157:H7 strain 8368     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5226038..5237063
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4C39_RS26720 (A4C39_26720) rpmE 5228269..5228481 (-) 213 WP_000710769.1 50S ribosomal protein L31 -
  A4C39_RS26725 (A4C39_26725) priA 5228684..5230882 (+) 2199 WP_001301674.1 primosomal protein N' Machinery gene
  A4C39_RS26730 (A4C39_26730) cytR 5231038..5232063 (+) 1026 WP_000644904.1 DNA-binding transcriptional regulator CytR Regulator
  A4C39_RS26735 (A4C39_26735) ftsN 5232155..5233114 (+) 960 WP_000068837.1 cell division protein FtsN -
  A4C39_RS26740 (A4C39_26740) hslV 5233207..5233737 (+) 531 WP_000208242.1 ATP-dependent protease subunit HslV -
  A4C39_RS26745 (A4C39_26745) hslU 5233747..5235078 (+) 1332 WP_001293341.1 HslU--HslV peptidase ATPase subunit -
  A4C39_RS26750 (A4C39_26750) menA 5235145..5236071 (+) 927 WP_001308187.1 1,4-dihydroxy-2-naphthoate polyprenyltransferase -
  A4C39_RS26755 (A4C39_26755) rraA 5236164..5236649 (+) 486 WP_000872908.1 ribonuclease E activity regulator RraA -

Sequence

Protein


Download         Length: 341 a.a.        Molecular weight: 37819.78 Da        Isoelectric Point: 6.3842

>NTDB_id=168875 A4C39_RS26730 WP_000644904.1 5231038..5232063(+) (cytR) [Escherichia coli O157:H7 strain 8368]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide


Download         Length: 1026 bp        

>NTDB_id=168875 A4C39_RS26730 WP_000644904.1 5231038..5232063(+) (cytR) [Escherichia coli O157:H7 strain 8368]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAAGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGTGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTGCCTACCGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGTTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, lacI family (LacI)

(11-56)

Periplasmic binding protein-like domain (Peripla_BP_3)

(176-337)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0ACN8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

64.179

98.24

0.63
  cytR Vibrio cholerae C6706

65.443

95.894

0.628