Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   AWB63_RS04310 Genome accession   NZ_CP014144
Coordinates   877081..879351 (+) Length   756 a.a.
NCBI ID   WP_060775854.1    Uniprot ID   -
Organism   Streptococcus salivarius strain JF     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 872081..884351
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AWB63_RS04285 (AWB63_04285) - 873183..873659 (-) 477 WP_037599232.1 ferrous iron transport protein A -
  AWB63_RS04290 (AWB63_04290) - 873831..874565 (-) 735 WP_002886191.1 amino acid ABC transporter ATP-binding protein -
  AWB63_RS04295 (AWB63_04295) - 874565..875245 (-) 681 WP_002886081.1 amino acid ABC transporter permease -
  AWB63_RS04300 (AWB63_04300) - 875559..875789 (-) 231 WP_002885970.1 DUF1797 family protein -
  AWB63_RS04305 (AWB63_04305) argF 875858..876838 (-) 981 WP_038675579.1 ornithine carbamoyltransferase -
  AWB63_RS04310 (AWB63_04310) clpE 877081..879351 (+) 2271 WP_060775854.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  AWB63_RS04315 (AWB63_04315) - 879494..879952 (+) 459 WP_038675574.1 NUDIX hydrolase -
  AWB63_RS04320 (AWB63_04320) - 879962..880264 (+) 303 WP_002885967.1 DUF1827 family protein -
  AWB63_RS04325 (AWB63_04325) - 880310..881272 (-) 963 WP_038675572.1 Gfo/Idh/MocA family protein -
  AWB63_RS04330 (AWB63_04330) - 881370..882605 (-) 1236 WP_038675570.1 aminoacyltransferase -
  AWB63_RS04335 (AWB63_04335) - 882583..883266 (-) 684 WP_002890375.1 TVP38/TMEM64 family protein -
  AWB63_RS10420 (AWB63_04340) - 883349..883717 (-) 369 Protein_836 DUF3862 domain-containing protein -

Sequence

Protein


Download         Length: 756 a.a.        Molecular weight: 83973.05 Da        Isoelectric Point: 5.0549

>NTDB_id=168732 AWB63_RS04310 WP_060775854.1 877081..879351(+) (clpE) [Streptococcus salivarius strain JF]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQNCYKIMKSDPENPLNQFNQTGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGGNTQGPGRPGGPRQQAPQQPQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGSVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNAG
DGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAI
TAAAELSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
KQTIKDQDMPVITEKHIEAIVEQKTNIPVGDLKEKEQSQLLSLADDLKSHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEV
EKAHPDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAARENRTNSVLNQLGDFFSPEFMNRFD
GIIEFSALSKENLLTIVDLMLDNVNQRLANNGIHLSVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLENPN
EKDLKAVMTSKGHITIKSAKKAEKTAQKAETAKETD

Nucleotide


Download         Length: 2271 bp        

>NTDB_id=168732 AWB63_RS04310 WP_060775854.1 877081..879351(+) (clpE) [Streptococcus salivarius strain JF]
ATGCTCTGTCAAAACTGTAACCTTAATGAAGCTAGTATTCATTTGTATACCAATGTAAACGGTAATCAGCAACAAGTTGA
CCTCTGTCAAAATTGTTATAAAATCATGAAATCTGACCCAGAGAACCCCCTCAATCAATTCAATCAAACAGGAGGTTCAA
ACTTCTTCGATGATTTCTTCAGCGACCTAAATAACTTCCGTTCTTCTAACGGCGATCTTCCCAATACACCTCCAACACAA
GAAGGTGGTAACCGAGGAAACGGTGGCAATACACAAGGGCCAGGCCGTCCAGGAGGACCACGCCAACAAGCTCCTCAACA
GCCACAAGGTCTTCTTGAAGAGTTCGGCATTAACATCACTGACATCGCTCGTCGTGGAGACATTGATCCTGTTATTGGTC
GTGACGAGGAAATCATTCGTGTCATCGAAATTCTTAACCGCCGTACCAAGAACAACCCCGTCCTCATCGGTGAACCCGGT
GTCGGTAAGACTGCTGTTGTTGAAGGCCTAGCTCAAAAAATCGTTGACGGTAGCGTGCCACAAAAACTCCAAGGCAAACA
AGTCATCCGTCTTGATGTGGTCAGCCTGGTTCAAGGGACTGGTATTCGTGGCCAATTTGAAGAACGCATGCAAAAACTCA
TGGAAGAAATTCGTCAACGTCAGGATGTTATCCTATTTATTGATGAAATCCATGAAATCGTAGGAGCTGGTAATGCTGGT
GATGGCAATATGGATGCTGGAAACATCCTAAAACCTGCTCTTGCTCGTGGAGAACTTCAACTGGTCGGAGCAACAACACT
CAACGAATACCGCATCATCGAAAAAGATGCCGCCCTAGAGCGTCGTATGCAACCAGTTAAGGTTGACGAACCAACGGTTG
AGGAAACCATCACTATTTTGCGTGGTATTCAACCTAAATATCAGGACTACCACCACGTCAAATATACAGACGAAGCGATT
ACTGCAGCTGCAGAATTGTCCAACCGCTACATTCAAGACCGCTTCTTGCCAGACAAGGCCATCGACCTCCTCGATGAAGC
TGGTTCGAAGATGAATTTGACCCTCAATTTTGTTGATCCTAAAGATATCGACAAACGTTTGATTGAGGCTGAAAACCTCA
AGGCTCAAGCTACTCGTGACGAAGACTTTGAAAAAGCTGCCTATTTCCGTGATCAAATTGCCAAATACAAGGAAATGCAA
AAACAAACCATCAAAGACCAAGATATGCCTGTCATCACAGAAAAACATATCGAAGCCATTGTGGAACAAAAAACCAATAT
TCCTGTCGGTGATTTGAAAGAAAAAGAACAATCACAACTTCTTAGTCTTGCTGATGATCTTAAATCACATGTTATTGGAC
AAGATGCCGCAGTTGATAAGATTGCCAAAGCCATCCGCCGTAATCGTGTTGGATTGGGTGCACCAAATCGCCCAATTGGT
AGCTTCCTCTTCGTAGGTCCTACAGGAGTCGGTAAAACTGAACTCTCTAAACAATTGGCGATTGAACTCTTTGGTTCAGC
TGACAGTATGATTCGTTTCGACATGTCAGAATACATGGAAAAACACGCCGTTGCCAAATTAGTCGGTGCCCCTCCAGGAT
ATGTCGGTTACGACGAAGCTGGTCAGTTAACTGAAAAAGTCCGCCGTAATCCTTATTCACTCATTCTTCTGGATGAGGTT
GAAAAAGCTCACCCAGATGTTCTTCACATGTTCCTCCAAGTACTTGACGATGGTCGTTTGACTGATGGTCAAGGACGCAC
TGTAAGTTTCAAAGATACCATTATCATCATGACATCAAATGCTGGTACCGGTAAAGTTGAAGCTAGCGTCGGCTTTGGAG
CTGCCCGTGAAAATCGTACCAATTCTGTTCTTAACCAGCTTGGAGATTTCTTCAGCCCTGAATTTATGAACCGCTTTGAC
GGTATTATCGAATTCTCTGCCCTTAGCAAGGAAAATCTCCTTACTATCGTGGACCTCATGCTTGACAATGTCAACCAACG
CTTGGCTAACAACGGTATCCACCTCAGTGTAACCGATAAGGTTAAGGAGAAATTGGTTGACCTTGGTTATGATCCTAAGA
TGGGGGCTCGACCACTACGTCGTACCATCCAAGATCATATTGAAGATGCTATCACTGACTTCTACCTTGAAAATCCAAAC
GAAAAAGATCTCAAGGCAGTCATGACTTCAAAAGGTCACATCACCATTAAGTCTGCTAAAAAAGCCGAAAAAACTGCTCA
GAAAGCTGAGACAGCAAAAGAAACTGATTAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(154-274)

AAA lid domain (AAA_lid_9)

(292-390)

AAA domain (Cdc48 subfamily) (AAA_2)

(477-640)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(648-721)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.714

100

0.857
  clpE Streptococcus pneumoniae Rx1

83.4

99.603

0.831
  clpE Streptococcus pneumoniae D39

83.4

99.603

0.831
  clpE Streptococcus pneumoniae R6

83.4

99.603

0.831
  clpE Streptococcus pneumoniae TIGR4

83.4

99.603

0.831
  clpC Lactococcus lactis subsp. cremoris KW2

77.424

99.603

0.771
  clpC Bacillus subtilis subsp. subtilis str. 168

52.006

85.714

0.446
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.189

86.772

0.401
  clpC Streptococcus pneumoniae Rx1

47.36

82.672

0.392
  clpC Streptococcus pneumoniae D39

47.36

82.672

0.392
  clpC Streptococcus pneumoniae TIGR4

47.2

82.672

0.39
  clpC Streptococcus thermophilus LMD-9

47.04

82.672

0.389
  clpC Streptococcus thermophilus LMG 18311

46.72

82.672

0.386
  clpC Streptococcus mutans UA159

46.486

82.804

0.385

Multiple sequence alignment