Detailed information NTG0168708

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AWB63_RS00280
• Genome accession: NZ_CP014144
• Coordinates: 35252..37702 (+)
• Length: 816 a.a.
• NCBI ID: WP_022496764.1
• Uniprot ID: A0AB33ZC83
• Organism: Streptococcus salivarius strain JF
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 30252..42702

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AWB63_RS00255 (AWB63_00255)	ahpC	31148..31708 (-)	561	WP_022496765.1	alkyl hydroperoxide reductase subunit C	-
AWB63_RS00260 (AWB63_00260)	rpsB	31981..32748 (+)	768	WP_002886342.1	30S ribosomal protein S2	-
AWB63_RS00265 (AWB63_00265)	tsf	32859..33899 (+)	1041	WP_002886343.1	translation elongation factor Ts	-
AWB63_RS00270 (AWB63_00270)	-	34008..34478 (-)	471	WP_004182164.1	COG2426 family protein	-
AWB63_RS00275 (AWB63_00275)	-	34796..35251 (+)	456	WP_014633783.1	CtsR family transcriptional regulator	-
AWB63_RS00280 (AWB63_00280)	clpC	35252..37702 (+)	2451	WP_022496764.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
AWB63_RS00285 (AWB63_00285)	pbp3	37832..39088 (-)	1257	WP_022496763.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
AWB63_RS00290 (AWB63_00290)	pbp3	39233..40480 (-)	1248	WP_022496762.1	D-alanyl-D-alanine carboxypeptidase PBP3	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90138.49 Da
• Isoelectric Point: 6.0145

>NTDB_id=168708 AWB63_RS00280 WP_022496764.1 35252..37702(+) (clpC) [Streptococcus salivarius strain JF]
MTTYSRKMQAIFHRAQLEAERFGSPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIRAEEIETAAVLAMEKSPKDLSESDI
IDLRAQSHALGAMLQEAEGIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERYAGLS
KQDLKAIHDLRKPKKSKASGNFANMMQPPQSSTGELSDYTKDLTAVAESGALDPVIGREKEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVAEAIDILKGLRSSYEDYHRVTI
TDEAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQGRIKKEAKLEITPLDEALLSGDMKAAVKQYKASQKAKLPKPAL
VDADQIMQTLSRLSGIPVEKMTQADSKRYLNLEAELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGARDISHNHQAMQSRIMEELKKAYRPEFINRIDEKVV
FHSLEEEQLREIVKIMVKPLVSALAEKGIDLKFQPAALKHLAKDGYDVEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=168708 AWB63_RS00280 WP_022496764.1 35252..37702(+) (clpC) [Streptococcus salivarius strain JF]
ATGACGACATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAGGCAGAGCGTTTTGGAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCAGGATCTGTAGCCTACCTAACATTTACTGATTTTGAGGACC
GTATTCGTGCGGAAGAGATTGAGACCGCTGCTGTACTAGCGATGGAGAAAAGTCCAAAAGACTTGTCTGAATCAGATATT
ATCGATTTACGTGCACAGTCACATGCTTTAGGGGCTATGTTGCAAGAGGCAGAGGGAATTGCTAGTGTAACTGGTGCTGT
AGAGGTAGGGTCTGAACATGTATTGATGGCCTTTCTCCTTCATAAGGATTTGATGGTTTGTCGTCTCCTTGAAGTTGCTG
GTTTTCAATATAAGGATGACAGCGATAAGCCTCGCATTATCGATTTACGACGTTCTTTGGAGCGTTACGCAGGTCTTAGT
AAGCAAGATTTGAAGGCCATTCACGACCTTCGTAAGCCTAAAAAGTCAAAGGCATCAGGTAATTTTGCTAATATGATGCA
GCCTCCTCAATCTTCTACTGGGGAACTGTCAGATTACACAAAAGACTTAACGGCAGTAGCCGAGTCAGGTGCTCTTGATC
CTGTTATTGGACGTGAGAAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAACCCAGTTCTTGTG
GGTGAAGCAGGTGTTGGTAAGACGGCACTTGCGCTTGGCTTAGCACAGCGTATTGCTTCAGGCGAAGTACCTTTTGAGTT
GGCTGATATGCGTATCTTAGAGCTTGATATGATGAGTGTGGTTGCAGGAACACGTTTCCGTGGCGATTTCGAAGAACGTA
TGAATCAGATCATTGATGAGATTGAAGCTGATGGAAAAATCATTCTCTTTATTGACGAATTGCATACGATTATCGGTTCT
GGTTCAGGTATTGATAGTACCTTAGATGCGGCGAATATTTTGAAACCCGCTCTAGCACGTGGAACCCTTCATATGGTTGG
AGCAACTACTCAAGCTGAGTACCAGAAGCATATTGAGAAAGATGCAGCTCTTTCTCGCCGTTTTGCTAAGATTACAATCG
AGGAGCCAAGTGTAGCTGAGGCGATTGATATTCTAAAAGGCCTACGGTCGTCTTATGAAGACTATCATCGTGTAACGATT
ACTGATGAGGCGGTTGAGACAGCAGTCAAGGCAGCCCACCGTTATTTGACGAGTAAAAACTTACCTGACTCTGCCATTGA
CCTTTTAGATGAAGCGAGTGCAACTGTTCAAGGTCGTATCAAAAAAGAAGCCAAACTTGAAATAACGCCTTTGGACGAAG
CGCTTCTATCTGGTGATATGAAGGCTGCTGTTAAACAATATAAGGCTAGCCAAAAAGCAAAATTACCAAAACCTGCCTTG
GTAGATGCAGATCAGATTATGCAAACCCTTAGTCGTCTATCAGGTATTCCTGTTGAGAAGATGACTCAGGCAGATAGCAA
GCGTTACTTGAATCTGGAAGCAGAGCTTCACAAACGTGTTATTGGTCAAGACGAAGCAGTTTCAGCGATTAGTCGTGCTA
TTCGTCGTAACCAGTCAGGTATTCGTACTGGCAAACGTCCGATTGGTTCCTTCATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAATTGGCCAAGGCTTTGGCGGAGGTTCTCTTTGATGATGAGTCAGCTTTGCTTCGCTTTGACATGTCAGAATA
CATGGAAAAATTTGCGGCTAGCCGCCTTAACGGTGCTCCTCCAGGTTATGTTGGATATGATGAGGGTGGTGAGTTAACAG
AAAAAGTTCGTAACAAGCCTTACTCAGTTCTTCTTTTTGACGAGGTAGAAAAGGCTCACCCAGACATTTTCAACATTCTC
TTACAGGTTTTGGATGATGGTGTCTTGACGGATAGTCGAGGTCGTAAAGTCGACTTCTCAAATACCATTATCATAATGAC
TTCGAACTTGGGGGCGACTGCTCTTCGCGATGATAAGACTGTTGGTTTTGGTGCTCGAGACATTTCTCATAATCATCAAG
CTATGCAGTCACGTATCATGGAAGAGCTTAAGAAGGCCTACCGTCCAGAGTTTATCAACCGTATTGATGAGAAGGTTGTC
TTCCATAGCTTAGAGGAAGAACAGCTTCGTGAGATTGTCAAAATTATGGTAAAACCGTTGGTTTCAGCTTTGGCTGAAAA
AGGGATTGACTTGAAATTCCAACCAGCTGCCCTCAAGCATTTGGCTAAAGATGGCTATGATGTTGAGATGGGTGCTCGTC
CATTACGTCGCACGATTCAAACTCAGGTTGAGGATAAGTTATCTGAGCTCTTACTAGGCGGCCAAGTAGTGAGTGGACAA
ACCCTTAAGATTGGTTGTTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (108-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

• AAA lid domain (AAA_lid_9) (377-455)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	95.098	100	0.951
clpC	Streptococcus thermophilus LMD-9	94.975	100	0.95
clpC	Streptococcus mutans UA159	73.039	100	0.73
clpC	Streptococcus pneumoniae TIGR4	67.525	100	0.675
clpC	Streptococcus pneumoniae Rx1	67.525	100	0.675
clpC	Streptococcus pneumoniae D39	67.525	100	0.675
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.464	100	0.509
clpC	Bacillus subtilis subsp. subtilis str. 168	46.902	100	0.473
clpE	Streptococcus mutans UA159	47.673	76.348	0.364
clpC	Lactococcus lactis subsp. cremoris KW2	44.781	81.005	0.363