Detailed information NTG0168680

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: AV541_RS08520
• Genome accession: NZ_CP014141
• Coordinates: 1565922..1566836 (+)
• Length: 304 a.a.
• NCBI ID: WP_008631687.1
• Uniprot ID: H7GF55
• Organism: Thermus parvatiensis strain RL
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1560922..1571836

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AV541_RS08495 (AV541_08500)	prmC	1561137..1562032 (+)	896	Protein_1704	peptide chain release factor N(5)-glutamine methyltransferase	-
AV541_RS08500 (AV541_08505)	-	1561931..1563274 (-)	1344	WP_060384692.1	DUF3084 domain-containing protein	-
AV541_RS08505 (AV541_08510)	lptB	1563277..1564005 (-)	729	WP_060384693.1	LPS export ABC transporter ATP-binding protein	-
AV541_RS08510 (AV541_08515)	gltX	1564060..1565465 (+)	1406	Protein_1707	glutamate--tRNA ligase	-
AV541_RS08515 (AV541_08520)	-	1565482..1565922 (+)	441	WP_060384694.1	hypothetical protein	-
AV541_RS08520 (AV541_08525)	pilA	1565922..1566836 (+)	915	WP_008631687.1	signal recognition particle-docking protein FtsY	Machinery gene
AV541_RS08525 (AV541_08530)	-	1566906..1567331 (+)	426	WP_008631686.1	disulfide bond formation protein B	-
AV541_RS08530 (AV541_08535)	-	1567276..1567761 (-)	486	WP_038035140.1	hypothetical protein	-
AV541_RS08535 (AV541_08540)	-	1567801..1568031 (+)	231	WP_008631684.1	hypothetical protein	-
AV541_RS08540 (AV541_08545)	guaB	1568028..1569508 (-)	1481	Protein_1713	IMP dehydrogenase	-
AV541_RS08545 (AV541_08550)	-	1569653..1570572 (+)	920	Protein_1714	carbohydrate kinase family protein	-
AV541_RS08550 (AV541_08555)	hisH	1570543..1571139 (-)	597	WP_060384695.1	imidazole glycerol phosphate synthase subunit HisH	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 32693.15 Da
• Isoelectric Point: 9.6959

>NTDB_id=168680 AV541_RS08520 WP_008631687.1 1565922..1566836(+) (pilA) [Thermus parvatiensis strain RL]
MGLFDRLRAGLAKTRERLLKAIPWGGDPEEVLEELEMALLAADVGVAATEELLKEVRASGRRDLKEVVKEKLVQMLEPDE
RRATLRKLGFRPQKLRPVEPKGHVVMVVGVNGVGKTTTIAKLGRLYQGLGKKVLFCAGDTFRAAGGAQLAEWGKRLGIPV
IQGPEGADPAALAFDAAQARKARGLDLLFVDTAGRLHTKQGLMEELKKVKRAIAKADPGEPGEVWLVLDAVTGQNGLEQA
KRFHEAVGLTGVIVTKLDGTAKGGVLVPIVRTLKVPIRFIGVGEGPDDLQPFDAEAFVEALLEA

Nucleotide

• Length: 915 bp

>NTDB_id=168680 AV541_RS08520 WP_008631687.1 1565922..1566836(+) (pilA) [Thermus parvatiensis strain RL]
ATGGGCCTCTTTGACCGGCTCAGGGCGGGCCTCGCCAAGACCCGGGAAAGGCTCCTCAAGGCCATCCCCTGGGGCGGCGA
CCCCGAGGAGGTCCTGGAGGAGCTGGAGATGGCCCTCCTCGCCGCCGACGTGGGGGTGGCGGCCACGGAGGAGCTCCTCA
AGGAGGTGCGGGCCTCGGGGCGGCGGGACCTGAAAGAGGTGGTGAAGGAGAAGCTCGTCCAGATGCTGGAGCCGGACGAG
CGGCGGGCCACACTGAGGAAGCTCGGCTTCCGTCCCCAGAAGCTCCGCCCCGTGGAGCCTAAGGGGCACGTGGTGATGGT
GGTGGGGGTGAACGGGGTGGGCAAGACCACCACCATCGCCAAGCTGGGCCGCCTCTACCAGGGCCTCGGCAAGAAGGTCC
TCTTCTGCGCCGGGGACACCTTCCGCGCCGCAGGGGGAGCCCAGCTCGCGGAGTGGGGGAAGCGCCTCGGGATCCCGGTG
ATCCAGGGCCCCGAGGGGGCGGACCCCGCCGCCCTCGCCTTTGACGCCGCCCAGGCCCGCAAAGCCCGGGGCCTGGACCT
CCTCTTCGTGGACACCGCGGGCCGCCTCCACACCAAGCAGGGCCTCATGGAGGAGCTCAAGAAGGTGAAGCGGGCCATCG
CCAAAGCGGACCCCGGGGAGCCGGGGGAGGTGTGGCTCGTGCTGGACGCCGTCACCGGGCAGAACGGCCTGGAGCAGGCC
AAGCGCTTCCACGAGGCCGTGGGCCTCACCGGGGTCATCGTCACCAAGCTGGACGGGACGGCCAAGGGCGGGGTCCTGGT
CCCCATCGTCCGCACCCTAAAGGTGCCCATCCGCTTCATCGGCGTGGGGGAAGGCCCGGACGACCTCCAGCCCTTTGACG
CCGAGGCCTTCGTGGAGGCCCTTCTCGAGGCCTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (103-302)

• SRP54-type protein, helical bundle domain (SRP54_N) (29-65)

3D structure

• AlphaFold DB: H7GF55

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	49.363	100	0.51