Detailed information    

insolico Bioinformatically predicted

Overview

Name   recD/recD2/recDB   Type   Machinery gene
Locus tag   WH25_RS02185 Genome accession   NZ_CP017295
Coordinates   440627..442981 (-) Length   784 a.a.
NCBI ID   WP_046164936.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 435627..447981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS02160 (WH25_02160) - 436855..437169 (+) 315 WP_046164931.1 hypothetical protein -
  WH25_RS02165 (WH25_02165) - 437488..438282 (+) 795 WP_046164932.1 CPBP family intramembrane glutamic endopeptidase -
  WH25_RS02170 (WH25_02170) - 438328..439122 (+) 795 WP_046164933.1 CPBP family intramembrane glutamic endopeptidase -
  WH25_RS02175 (WH25_02175) - 439112..439861 (+) 750 WP_046164934.1 CPBP family intramembrane glutamic endopeptidase -
  WH25_RS02180 (WH25_02180) - 439937..440575 (+) 639 WP_046164935.1 TetR/AcrR family transcriptional regulator -
  WH25_RS02185 (WH25_02185) recD/recD2/recDB 440627..442981 (-) 2355 WP_046164936.1 ATP-dependent RecD-like DNA helicase Machinery gene
  WH25_RS02190 (WH25_02190) lepB 443075..443677 (-) 603 WP_011999786.1 signal peptidase I -
  WH25_RS02195 (WH25_02195) rnhC 443681..444571 (-) 891 WP_045634572.1 ribonuclease HIII -
  WH25_RS02200 (WH25_02200) - 444722..445027 (+) 306 WP_008808274.1 hypothetical protein -
  WH25_RS02205 (WH25_02205) - 445027..445575 (+) 549 WP_045634571.1 CvpA family protein -
  WH25_RS02210 (WH25_02210) mutS/mutS2 445631..447964 (+) 2334 WP_046164937.1 endonuclease MutS2 Machinery gene

Sequence

Protein


Download         Length: 784 a.a.        Molecular weight: 87923.92 Da        Isoelectric Point: 4.5736

>NTDB_id=167965 WH25_RS02185 WP_046164936.1 440627..442981(-) (recD/recD2/recDB) [Streptococcus gordonii strain IE35]
MEFYFSGTVERIIFENPNNFFRILLLDIEDTDAEFDDFEIIVTGTMADIMEGQDYTFWGTLVQHPKYGEQLKVTRYERAK
PSSKGLVKYFASDHFKGIGVKTAQKIVDLYGDNTIDQILADPGRLVTINGLSSANREAFVSKLRQNYGTEMLLSKLAEYG
IPNKLALQIQDTYKEETLEIVQKYPYQLVEDIQGIGFKIADQLAQQLGIESDAPERFRAGLVHTLFSQSIETGDTYIEAR
DLLSHTIDLLENARQVELDPALVADELAHLIEEDKIQNVETKIFENSLYFAEEGIRSNLIRILEKGKQETFDAPKLESII
EQVEQDLGICYDHIQKKAICDAINHKVFILTGGPGTGKTTVINGIIATYAALHKLDLAKKQELPILLAAPTGRAARRMNE
LTGLPSATIHRHLGMTGDDDTSHLDDYLDADFIIVDEFSMVDTWLANQLLSNISSNSKILIVGDADQLPSVSPGQVLADL
LKIPLLPQTKLSKIYRQGEDSTIVTLASQIQQGLLPADFTEKKADRSYFEATSEYIPDMIKKIVAAAIRSGIPAQDVQVL
APMYRGPAGIDQINQLMQDLINPSEKDQLVFEAPDCQYRQGDKVIHLVNDAESNVFNGDLGYITDLLPGKYTDSKQDELT
INVDGNEIIYPRSEWYKIRLAYAMSIHKSQGSEFPVVILPITRSSHRMLQRNLVYTAITRAKSKLILLGEKAAFDYAAKN
TGTARKTYLVERFADLEAPQELSYTPVDRLEKAVENYVLTEENFLKIDPLIGLTEEDIHSIFST

Nucleotide


Download         Length: 2355 bp        

>NTDB_id=167965 WH25_RS02185 WP_046164936.1 440627..442981(-) (recD/recD2/recDB) [Streptococcus gordonii strain IE35]
ATGGAATTCTATTTTTCAGGAACCGTCGAACGCATTATATTTGAAAATCCCAACAATTTCTTTCGAATTTTGTTACTGGA
TATCGAGGACACAGATGCAGAATTTGATGATTTTGAGATTATCGTGACCGGAACCATGGCCGATATCATGGAAGGACAAG
ACTACACTTTTTGGGGAACTCTTGTTCAACATCCCAAATACGGGGAACAGCTAAAAGTAACTCGCTACGAAAGAGCAAAG
CCAAGCAGTAAGGGTCTAGTCAAGTATTTTGCTAGCGATCATTTTAAAGGGATCGGTGTTAAGACCGCCCAAAAAATAGT
AGACCTCTATGGCGATAATACGATTGACCAGATCTTGGCCGATCCTGGCCGGCTCGTAACTATTAATGGCCTTTCTTCAG
CCAATCGGGAAGCCTTCGTCAGCAAACTGAGACAAAATTATGGCACTGAGATGTTGCTCTCTAAACTCGCTGAATATGGC
ATCCCCAATAAACTAGCCTTACAGATTCAAGATACCTACAAGGAAGAAACTTTGGAAATTGTCCAAAAATATCCTTATCA
ACTGGTTGAAGACATTCAAGGTATTGGTTTCAAAATAGCTGACCAGTTGGCCCAGCAACTTGGTATTGAAAGCGACGCTC
CAGAGCGTTTCCGGGCTGGGCTTGTTCATACCCTTTTCAGCCAATCTATAGAGACAGGTGATACTTATATAGAAGCACGT
GACTTGCTATCCCACACCATTGATTTGCTGGAGAATGCCCGGCAGGTTGAACTTGATCCTGCCTTGGTAGCGGATGAATT
GGCCCACCTTATCGAAGAAGATAAGATTCAAAATGTTGAAACAAAAATCTTTGAAAACAGTCTTTATTTCGCCGAGGAAG
GTATCCGTAGCAATCTGATTCGGATTCTAGAAAAAGGCAAACAAGAAACCTTTGATGCCCCAAAACTCGAAAGTATCATC
GAACAAGTCGAGCAAGATTTAGGAATCTGCTATGACCATATTCAAAAGAAGGCCATCTGCGATGCCATTAATCATAAGGT
GTTTATTCTGACGGGTGGGCCAGGAACTGGTAAAACGACCGTTATCAATGGCATCATCGCTACTTATGCTGCTCTTCACA
AACTAGATTTAGCTAAGAAACAGGAATTACCTATTCTGCTTGCTGCTCCAACTGGACGAGCTGCCCGACGAATGAATGAA
TTAACTGGACTCCCCAGCGCTACTATTCACCGACATTTGGGGATGACTGGAGATGACGATACCAGCCATTTAGATGACTA
TTTGGATGCTGATTTCATCATTGTGGATGAGTTCTCTATGGTCGATACTTGGCTGGCCAATCAACTGCTCAGCAATATTT
CTTCCAACAGTAAAATCCTTATTGTAGGGGATGCTGACCAGCTTCCGTCTGTCAGTCCCGGTCAGGTTCTGGCCGATCTT
TTAAAAATACCTCTCTTACCCCAAACTAAACTATCAAAAATCTACCGGCAGGGAGAAGATTCAACAATCGTTACCCTGGC
CAGTCAAATCCAGCAAGGACTTCTGCCGGCTGATTTTACTGAAAAAAAAGCGGATCGATCCTATTTTGAAGCAACTAGTG
AATATATCCCTGACATGATTAAGAAAATCGTAGCCGCCGCCATTCGCAGTGGTATCCCTGCCCAGGACGTCCAAGTCCTG
GCTCCTATGTACCGAGGACCCGCAGGAATCGACCAGATCAACCAACTCATGCAGGATTTGATAAATCCATCAGAAAAAGA
CCAACTGGTCTTTGAAGCGCCAGACTGCCAATACCGGCAAGGGGACAAGGTCATTCATCTGGTCAACGATGCCGAAAGCA
ATGTCTTTAACGGCGATCTGGGCTATATCACCGACCTCTTGCCTGGCAAATACACCGACTCCAAGCAGGACGAGCTGACC
ATCAACGTTGACGGCAATGAAATCATCTACCCGCGCAGCGAATGGTACAAGATCCGCCTAGCCTATGCCATGAGTATCCA
CAAGTCTCAGGGCAGCGAGTTTCCCGTGGTCATCCTACCTATCACCCGTAGCAGCCACCGCATGCTCCAGCGCAATCTGG
TCTACACAGCCATTACCCGGGCCAAGAGCAAGCTGATCCTGCTTGGGGAAAAAGCAGCCTTTGACTATGCTGCAAAAAAC
ACTGGCACCGCCCGCAAAACCTATCTGGTCGAGCGTTTTGCTGACCTAGAAGCTCCACAGGAACTTAGCTACACTCCTGT
GGATAGGTTGGAAAAAGCTGTGGAAAACTATGTCTTGACAGAAGAAAATTTCCTGAAAATCGACCCCCTAATCGGCCTGA
CCGAGGAAGATATCCACAGTATATTCAGCACATAA

Domains

Predicted by InterProScan.

UvrD-like helicase C-terminal domain (UvrD_C_2)

(661-708)

AAA domain (AAA_30)

(334-526)

Helix-hairpin-helix containing domain (HHH_RecD2)

(146-236)

ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13)

(573-641)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recD/recD2/recDB Bacillus subtilis subsp. subtilis str. 168

40.909

98.214

0.402

Multiple sequence alignment