Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   A4W86_RS07185 Genome accession   NZ_CP017272
Coordinates   1419803..1420435 (-) Length   210 a.a.
NCBI ID   WP_016265428.1    Uniprot ID   -
Organism   Latilactobacillus sakei strain TMW 1.1239     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1414803..1425435
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4W86_RS07155 (A4W86_07095) - 1415034..1416125 (-) 1092 WP_011375058.1 ABC transporter ATP-binding protein -
  A4W86_RS07160 (A4W86_07100) - 1416281..1417276 (+) 996 WP_016265424.1 YhdH/YhfP family quinone oxidoreductase -
  A4W86_RS07165 (A4W86_07105) - 1417331..1417549 (-) 219 WP_016265425.1 CsbD family protein -
  A4W86_RS07170 (A4W86_07110) - 1417624..1418289 (-) 666 WP_056947232.1 ABC transporter ATP-binding protein -
  A4W86_RS07175 (A4W86_07115) - 1418291..1419349 (-) 1059 WP_016265427.1 ABC transporter permease -
  A4W86_RS07180 (A4W86_07120) - 1419484..1419777 (-) 294 WP_011375063.1 iron-sulfur cluster biosynthesis protein -
  A4W86_RS07185 (A4W86_07125) vraR 1419803..1420435 (-) 633 WP_016265428.1 response regulator transcription factor Regulator
  A4W86_RS07190 (A4W86_07130) - 1420437..1421501 (-) 1065 WP_016265429.1 sensor histidine kinase -
  A4W86_RS07195 (A4W86_07135) liaF 1421498..1422256 (-) 759 WP_016265430.1 cell wall-active antibiotics response protein LiaF -
  A4W86_RS07200 (A4W86_07140) greA 1422779..1423252 (-) 474 WP_011375067.1 transcription elongation factor GreA -
  A4W86_RS07205 (A4W86_07145) udk 1423274..1423948 (-) 675 WP_257875865.1 uridine kinase -
  A4W86_RS07210 (A4W86_07150) mltG 1423988..1425139 (-) 1152 WP_016265432.1 endolytic transglycosylase MltG -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23359.95 Da        Isoelectric Point: 4.7642

>NTDB_id=167671 A4W86_RS07185 WP_016265428.1 1419803..1420435(-) (vraR) [Latilactobacillus sakei strain TMW 1.1239]
MIKVLIVDDHEMVRLGISTYLGVQDDLEVVDQAVNGREGVEKALALRPDAILMDLVMPEMDGIEATKTILKAWPQAKIII
LTSFIDDEKVYPAIEAGAASYILKTSTAEEIANTIRKTTAGQSVLEPEVTNKMMNRMTHQAETKLYEDLTNREREVLGLI
AKGRSNQEIADELFITLKTVKTHVSNILAKLQVDDRTQAAIYAIKHQLAD

Nucleotide


Download         Length: 633 bp        

>NTDB_id=167671 A4W86_RS07185 WP_016265428.1 1419803..1420435(-) (vraR) [Latilactobacillus sakei strain TMW 1.1239]
GTGATAAAAGTATTGATTGTAGATGACCACGAGATGGTTCGATTGGGGATTTCAACTTATTTAGGGGTGCAAGACGATTT
AGAAGTGGTCGATCAAGCGGTTAATGGTCGTGAAGGTGTCGAAAAGGCATTGGCACTACGGCCAGATGCGATTTTAATGG
ATCTCGTCATGCCTGAAATGGATGGGATTGAAGCCACTAAGACGATTCTAAAGGCTTGGCCTCAAGCCAAGATTATTATT
CTAACCAGCTTTATTGATGATGAAAAAGTCTACCCAGCAATCGAAGCTGGTGCAGCAAGTTACATATTAAAAACGTCGAC
GGCCGAAGAGATTGCCAACACGATTCGGAAGACAACTGCGGGGCAATCAGTTTTAGAACCTGAAGTCACTAATAAGATGA
TGAATCGTATGACGCATCAGGCAGAAACAAAGTTATACGAAGATTTAACGAACCGTGAACGAGAAGTCCTAGGTTTGATT
GCCAAGGGTCGCAGTAATCAAGAAATTGCGGATGAATTATTCATTACACTTAAAACGGTTAAGACGCATGTTTCCAATAT
TTTAGCGAAGTTACAAGTCGACGATCGGACGCAGGCCGCAATTTATGCCATCAAGCACCAATTAGCGGATTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

62.319

98.571

0.614
  degU Bacillus subtilis subsp. subtilis str. 168

36.53

100

0.381

Multiple sequence alignment