Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   A4W86_RS01950 Genome accession   NZ_CP017272
Coordinates   417992..420595 (+) Length   867 a.a.
NCBI ID   WP_076645117.1    Uniprot ID   -
Organism   Latilactobacillus sakei strain TMW 1.1239     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 412992..425595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4W86_RS01940 (A4W86_01925) - 415159..416988 (+) 1830 WP_016264636.1 APC family permease -
  A4W86_RS01945 (A4W86_01930) - 417164..417970 (+) 807 WP_016264637.1 TIGR00282 family metallophosphoesterase -
  A4W86_RS01950 (A4W86_01935) hexA 417992..420595 (+) 2604 WP_076645117.1 DNA mismatch repair protein MutS Machinery gene
  A4W86_RS01955 (A4W86_01940) hexB 420619..422580 (+) 1962 WP_035144579.1 DNA mismatch repair endonuclease MutL Machinery gene
  A4W86_RS01960 (A4W86_01945) - 422580..423125 (+) 546 WP_016264640.1 Maf family protein -
  A4W86_RS01965 (A4W86_01950) - 423138..423701 (+) 564 WP_016264641.1 TIGR00730 family Rossman fold protein -
  A4W86_RS01970 (A4W86_01955) ruvA 424076..424687 (+) 612 WP_016264642.1 Holliday junction branch migration protein RuvA Machinery gene

Sequence

Protein


Download         Length: 867 a.a.        Molecular weight: 96892.75 Da        Isoelectric Point: 5.2556

>NTDB_id=167617 A4W86_RS01950 WP_076645117.1 417992..420595(+) (hexA) [Latilactobacillus sakei strain TMW 1.1239]
MLQKTKETPMMAQYQKVKDQYPDAFLFYRLGDFYELFNDDAVKASQLLELTLTARNKNAADPIPMCGVPHHAAQNYIDIL
VDQGYKVAICEQMEDPKTAKGMVKREVVQLVTPGTVMDEKAGHAKQNNYLTAVVAQGDQFGFAYTDLSTGEMKVSQISSL
DVLLNEMLSLQTKEVVVNHDVPSEVVQAFVQQQILVSYQDEGADTAEVSFVSQNISQPLALAVIKQLVVYLATTQKRHLG
HLQRAQAYEPSQYLKLDHSAKMNLELTASLRTGHKSGTLLWLLDETKTAMGGRLLKQWLERPLLDLNQIKNRQNQVASFL
QHYFERTNLQEALTKVYDLERLAGRVAFGSVNGRDLIQLKTSLEQIPKIKDVLTGINETQAFDQALTRLDPVDDVRTLIE
TAINPDSPISVTDGGIIQDGYDEQLDQYRNAMSNGKQWLAQLEAQEREATGIHNLKIGFNRVFGYYIEVTRANLSSLPEG
RYERKQTLTNAERFITPELKEKEQLILEAEERSTALEYELFTQVREQVKLQIERLQTLAKGVAALDVLQSFAVVSESYHY
VQPTLRTDSREIDLVDGRHPVVEKVLGRQKYIPNAVQMGKETDMLLITGPNMSGKSTYMRQLALTVIMAQMGCFVPAKSA
NLPVFDQIFTRIGAADDLISGQSTFMVEMMEANRAIMSATANSLILFDEIGRGTATYDGMALAQAIIEYIHDHVHAKTLF
STHYHELTALADTLTALRNVHVGAVEENGELVFLHKMLAGPADKSYGIHVAKLAGMPETLLQRADVILGQLEDKPKAPVQ
PEIVVPAQPTAAAVEEQMALFEPEVAAPVDKKTDKVVAAIKNFDLMSATPLEALNQLYEWQKQLNKH

Nucleotide


Download         Length: 2604 bp        

>NTDB_id=167617 A4W86_RS01950 WP_076645117.1 417992..420595(+) (hexA) [Latilactobacillus sakei strain TMW 1.1239]
ATGCTGCAAAAAACAAAAGAAACGCCAATGATGGCCCAATATCAAAAGGTTAAGGATCAATATCCAGACGCCTTTTTATT
TTATAGATTGGGTGATTTTTACGAATTATTCAATGATGATGCTGTTAAAGCATCACAACTTTTAGAATTAACGCTGACAG
CGCGTAATAAGAATGCAGCAGACCCCATTCCGATGTGTGGTGTGCCCCATCATGCAGCGCAAAACTACATTGATATTTTA
GTGGATCAAGGTTACAAGGTCGCCATTTGTGAGCAGATGGAAGATCCTAAAACGGCTAAGGGCATGGTCAAACGCGAAGT
TGTCCAATTAGTAACACCTGGGACCGTGATGGACGAAAAAGCCGGTCACGCTAAACAAAATAATTATTTAACGGCAGTCG
TTGCACAAGGCGATCAATTTGGCTTTGCCTATACGGATTTATCCACAGGTGAAATGAAGGTTAGCCAAATCAGTAGTTTA
GATGTGTTATTAAACGAAATGTTGAGTTTACAAACCAAAGAAGTGGTTGTGAACCATGATGTCCCAAGCGAAGTCGTTCA
AGCCTTTGTCCAACAACAAATCTTGGTTTCTTATCAAGATGAGGGGGCCGATACGGCAGAGGTCAGTTTTGTTTCTCAAA
ATATCTCACAACCACTAGCATTAGCCGTCATTAAACAGTTAGTTGTTTATTTAGCAACGACGCAAAAGCGGCACTTGGGC
CATTTACAACGCGCCCAAGCCTATGAACCTTCTCAATACTTGAAGTTGGATCATTCGGCTAAGATGAACCTCGAATTAAC
GGCTTCATTACGAACTGGCCATAAGAGTGGGACGTTATTGTGGCTACTGGATGAAACAAAGACTGCGATGGGTGGTCGTT
TATTAAAACAATGGTTGGAACGACCATTGTTGGATTTAAACCAGATTAAGAACCGGCAAAACCAAGTCGCTAGTTTCTTA
CAGCACTATTTTGAAAGGACGAACCTTCAAGAAGCCCTAACCAAGGTTTATGATTTGGAACGTCTAGCGGGTCGCGTTGC
TTTTGGGAGCGTTAATGGTCGCGATTTGATTCAATTAAAAACATCCTTAGAACAGATTCCAAAGATTAAAGATGTTTTGA
CGGGCATTAACGAAACGCAGGCTTTTGATCAAGCGTTAACGCGTTTGGATCCAGTTGATGATGTGCGGACGTTAATTGAA
ACAGCGATTAACCCGGATTCACCGATTTCAGTGACTGATGGCGGGATTATTCAAGATGGTTACGACGAACAACTTGATCA
ATACCGCAATGCGATGTCTAACGGCAAGCAGTGGTTGGCGCAATTAGAGGCGCAAGAACGAGAAGCCACGGGCATTCATA
ATTTGAAAATCGGCTTTAACCGCGTCTTTGGGTATTATATCGAAGTCACGCGGGCTAACTTGAGTTCATTACCGGAAGGG
CGGTATGAACGCAAACAAACGTTAACCAACGCCGAACGATTCATCACACCGGAACTAAAAGAAAAAGAACAACTGATTTT
AGAGGCGGAAGAACGCTCAACCGCTTTAGAATACGAATTGTTTACCCAAGTTCGGGAACAAGTGAAGTTACAGATTGAAC
GGCTCCAAACATTGGCTAAAGGCGTAGCGGCCCTAGATGTCTTGCAAAGTTTTGCGGTCGTCAGCGAAAGCTACCACTAT
GTCCAACCAACATTAAGAACTGATAGTCGCGAAATTGATTTAGTCGATGGCCGTCATCCGGTGGTTGAAAAGGTATTGGG
ACGCCAAAAATATATCCCCAATGCTGTTCAAATGGGCAAAGAAACGGATATGTTATTAATTACCGGACCTAATATGTCTG
GTAAAAGTACCTACATGCGGCAATTGGCCTTAACGGTCATCATGGCGCAAATGGGTTGTTTTGTACCTGCCAAGTCAGCG
AACTTGCCTGTATTTGATCAAATTTTTACCCGCATTGGCGCGGCAGATGATTTGATTTCAGGACAAAGTACGTTTATGGT
AGAAATGATGGAAGCCAACCGTGCAATTATGAGTGCGACCGCCAATAGTTTAATTCTTTTCGATGAAATTGGTCGGGGAA
CGGCAACTTACGATGGAATGGCCTTGGCACAAGCGATTATCGAATATATCCATGATCACGTCCACGCCAAGACGCTCTTT
TCAACGCATTATCATGAATTGACGGCTTTAGCCGATACGTTGACCGCCCTCCGTAACGTGCATGTTGGTGCGGTTGAGGA
AAACGGCGAGTTGGTCTTCTTACACAAGATGTTGGCCGGACCTGCGGATAAGTCTTACGGGATTCATGTCGCTAAACTAG
CGGGCATGCCAGAAACCTTATTACAACGGGCCGATGTTATTTTAGGTCAGTTAGAAGATAAACCAAAAGCACCGGTGCAA
CCAGAAATAGTCGTACCAGCACAACCGACTGCAGCGGCTGTCGAAGAACAGATGGCGCTTTTTGAACCAGAAGTGGCGGC
CCCGGTCGATAAGAAAACAGATAAAGTGGTAGCGGCAATTAAGAATTTTGATTTGATGAGCGCCACACCACTAGAAGCCC
TCAATCAATTATATGAGTGGCAAAAGCAATTAAATAAACATTAA

Domains

Predicted by InterProScan.

MutS domain I (MutS_I)

(8-119)

MutS domain II (MutS_II)

(128-243)

MutS family domain IV (MutS_IV)

(420-512)

MutS domain V (MutS_V)

(605-792)

MutS domain III (MutS_III)

(263-552)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

52.079

99.885

0.52
  mutS Pseudomonas stutzeri strain ATCC 17587

38.655

100

0.391