Detailed information NTG0167501

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: BFO62_RS08180
• Genome accession: NZ_CP017257
• Coordinates: 1410978..1413557 (+)
• Length: 859 a.a.
• NCBI ID: WP_002220613.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain COL-201504-11
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1405978..1418557

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BFO62_RS08150 (BFO62_07440)	-	1406111..1406842 (+)	732	WP_002220620.1	surface lipoprotein assembly modifier	-
BFO62_RS08155 (BFO62_07445)	ppx	1406959..1408467 (+)	1509	WP_002220619.1	exopolyphosphatase	-
BFO62_RS08165 (BFO62_07450)	-	1408676..1409041 (-)	366	WP_002220617.1	Ag473 family lipoprotein	-
BFO62_RS08170 (BFO62_07455)	-	1409361..1409702 (-)	342	WP_002220616.1	hypothetical protein	-
BFO62_RS08175 (BFO62_07460)	trpS	1409708..1410718 (-)	1011	WP_002224583.1	tryptophan--tRNA ligase	-
BFO62_RS08180 (BFO62_07465)	clpC	1410978..1413557 (+)	2580	WP_002220613.1	ATP-dependent chaperone ClpB	Regulator
BFO62_RS08185 (BFO62_07470)	-	1413644..1414858 (-)	1215	WP_002220612.1	pyridoxal phosphate-dependent aminotransferase	-
BFO62_RS08190 (BFO62_07475)	-	1414947..1415156 (-)	210	WP_002212949.1	tautomerase family protein	-
BFO62_RS08195 (BFO62_07480)	-	1415501..1416307 (+)	807	WP_002212946.1	DUF4198 domain-containing protein	-
BFO62_RS08200 (BFO62_07485)	-	1416365..1417630 (-)	1266	WP_076612675.1	Glu/Leu/Phe/Val family dehydrogenase	-

Sequence

Protein

• Length: 859 a.a.
• Molecular weight: 95179.57 Da
• Isoelectric Point: 5.3090

>NTDB_id=167501 BFO62_RS08180 WP_002220613.1 1410978..1413557(+) (clpC) [Neisseria meningitidis strain COL-201504-11]
MRYDKLTAKFQQALAEAQSLALAADGSYLEAGFVLKALLDDQNSGAAALLAHSGVNVPQVKQRLQQHLNSLPKVSGQGGD
ILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDAVRGGQNVNDANAEDQRDA
LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVGEPSVENTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASR
VKMEKETKPEAMDKIDRRLIQLRMEKAHVEKEKDDASKKRLELIDEEINGLQKEYADLDEIWKAEKAISDGAANIKKQID
EVKIKIEQAKRQGDLALASKLMYEDLEHLEKQRAAAERADTDSTKPANKLLRNNVGAEEIAEVVSRMTGIPVSKMMEGER
DKLLKMEEVLHRRVVGQDEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSE
YMEKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVM
TSNIGSQHIQQMGIQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQDNIRNIAKIQLKGLEKRLEKQNLRLTVSD
AALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIRVEADGDRLKFA

Nucleotide

• Length: 2580 bp

>NTDB_id=167501 BFO62_RS08180 WP_002220613.1 1410978..1413557(+) (clpC) [Neisseria meningitidis strain COL-201504-11]
ATGCGATACGACAAATTAACCGCCAAATTCCAACAAGCCCTTGCAGAAGCTCAGAGTTTGGCGTTGGCTGCGGACGGCAG
CTATCTGGAAGCAGGCTTTGTGTTAAAAGCCCTGCTTGACGACCAAAACAGCGGAGCCGCCGCGTTGCTGGCGCATTCGG
GCGTGAACGTGCCGCAGGTGAAACAGCGTTTGCAGCAGCATTTGAACAGCCTGCCGAAAGTGTCCGGCCAGGGCGGCGAC
ATTCTGCCCAGCCGCGAATTGCAGGCGGTGTTGAACCTGATGGACAAAGCCGCAACCAAACGCGGCGATGCCTATATCGC
CAGTGAACTTTTCCTGCTTGCCTTGGTGCAGCAGAACGATGCGGCCGGCAAAATTTTGAAAGAAGCCGGCGCGACCGAAC
AAAACATCAATGCCGCAATCGATGCGGTACGAGGAGGACAAAACGTGAACGATGCCAATGCCGAAGACCAACGCGATGCG
CTGAAAAAATATACGCTTGACCTGACCCAGCGCGCCCGCGACGGCAAACTTGACCCCGTTATCGGCCGTGACGACGAAAT
CCGCCGCGCGATTCAAGTGCTGCAACGCCGCACCAAAAACAACCCCGTGCTGATTGGCGAACCGGGCGTGGGTAAAACTG
CCATTGTTGAAGGCTTGGCGCAACGTATCGTCAACGGCGAAGTGCCTGAATCCCTGCGTAACAAACGCCTTTTGGTTCTG
GACTTGGCGGCTTTGATTGCCGGCGCGAAATACCGCGGCGAATTTGAAGAACGCTTGAAAGGCGTGTTGAACGATTTGGC
GAAAGACGACGGCAACACTCTGATTTTCATCGACGAAATCCATACTTTGGTCGGCGCAGGCAAAACCGACGGTGCGATGG
ATGCGGGCAATATGCTGAAACCGGCTTTGGCACGTGGCGAATTGCACTGTATCGGCGCGACCACTTTGGACGAATACCGC
CAATACATCGAAAAAGATGCGGCACTCGAACGCCGCTTCCAAAAAGTATTGGTCGGCGAGCCAAGCGTGGAAAACACCAT
CGCTATTTTGCGCGGTTTACAGGAGCGTTATGAAATCCACCATGGTATCGATATTACCGACCCTGCTATCGTTGCCGCAG
CGGAGTTGAGCGACCGCTACATCACCGACCGCTTCCTGCCCGATAAAGCGATTGATTTGATTGACGAAGCCGCCAGCCGT
GTCAAGATGGAAAAAGAAACCAAGCCGGAAGCAATGGACAAAATCGACCGCCGTCTAATTCAGCTTCGGATGGAAAAGGC
GCACGTTGAAAAAGAAAAAGACGATGCCAGCAAAAAACGTTTGGAACTGATAGACGAGGAAATCAACGGTCTGCAAAAAG
AATACGCCGATTTAGACGAAATCTGGAAAGCCGAAAAAGCAATTTCAGACGGTGCTGCTAATATTAAGAAACAAATTGAC
GAAGTCAAAATTAAAATCGAACAGGCAAAACGGCAAGGCGATTTGGCACTGGCTTCAAAATTGATGTATGAAGATTTGGA
GCATTTGGAAAAACAGCGTGCAGCCGCCGAACGGGCAGATACGGACAGCACAAAACCGGCAAACAAACTCTTGCGTAATA
ATGTCGGCGCAGAGGAAATCGCAGAAGTTGTTTCCCGTATGACCGGCATTCCTGTGTCAAAAATGATGGAAGGCGAACGT
GACAAGTTGCTGAAAATGGAAGAAGTGTTGCACCGCCGCGTAGTCGGTCAAGACGAAGCCGTGCGTGCCGTGTCCGACGC
TATCCGCCGCAGCCGTTCCGGTCTTGCCGACCCGAATAAACCCTACGGCAGCTTCCTGTTCTTGGGCCCGACCGGCGTGG
GTAAGACCGAATTGTGCAAGGCATTGGCAGGCTTCCTGTTCGACAGCGAAGATCATCTGATTCGTATCGATATGTCCGAA
TACATGGAAAAACATGCTGTTGCCCGCCTAATTGGTGCGCCTCCGGGCTATGTCGGCTACGAAGAAGGCGGCTACCTGAC
TGAGCAAGTCCGCCGCAAACCATACAGCGTGATTCTTTTGGATGAAGTGGAAAAAGCCCATCCGGACGTGTTCAACATCC
TGCTGCAAGTATTGGATGACGGTCGTTTGACCGACGGGCAAGGCAGGACGGTAGATTTTAAAAATACCGTGATTGTGATG
ACTTCCAACATCGGCAGCCAGCACATCCAACAAATGGGCATTCAGGATTACGAAGCGGTAAAAGAAGTTGTGATGGAGGA
TGTGAAAGAACATTTCCGTCCTGAAATGATCAACCGCATCGACGAAGTGGTCGTGTTCCACGGACTGGATCAGGATAATA
TCCGCAACATTGCGAAAATCCAGCTCAAAGGCTTGGAAAAACGTTTGGAAAAACAAAACCTCCGCCTGACTGTTTCCGAT
GCCGCTCTGGACATCATCGCCAAAGCCGGTTTCGACCCGATTTACGGCGCACGTCCGCTCAAACGCGCCATCCAGTCGGA
AATCGAAAACCCGCTGGCAAAAGCCCTGCTTGCCGGAAACTATGCGCCCGAAAGCGAAATCAGGGTAGAAGCCGACGGCG
ACAGACTGAAATTTGCCTGA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• AAA domain (Cdc48 subfamily) (AAA_2) (601-763)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (769-849)

• AAA lid domain (AAA_lid_9) (342-442)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	43.902	100	0.44
clpC	Streptococcus pneumoniae Rx1	39.203	100	0.412
clpC	Streptococcus pneumoniae TIGR4	39.203	100	0.412
clpC	Streptococcus pneumoniae D39	39.203	100	0.412
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	38.573	100	0.403
clpC	Lactococcus lactis subsp. cremoris KW2	47.118	80.792	0.381
clpE	Streptococcus pneumoniae TIGR4	47.353	79.162	0.375
clpE	Streptococcus mutans UA159	45.322	79.627	0.361