Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   BFO62_RS00195 Genome accession   NZ_CP017257
Coordinates   28120..31143 (+) Length   1007 a.a.
NCBI ID   WP_025458702.1    Uniprot ID   -
Organism   Neisseria meningitidis strain COL-201504-11     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 23120..36143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFO62_RS00150 (BFO62_00115) pilA 23825..25090 (+) 1266 WP_002224230.1 signal recognition particle-docking protein FtsY Machinery gene
  BFO62_RS00165 (BFO62_00120) - 26069..26353 (+) 285 WP_002216166.1 GIY-YIG nuclease family protein -
  BFO62_RS12695 (BFO62_00125) - 27876..28034 (-) 159 WP_153317777.1 hypothetical protein -
  BFO62_RS00195 (BFO62_00130) pilC 28120..31143 (+) 3024 WP_025458702.1 PilC family type IV pilus tip adhesin Machinery gene
  BFO62_RS00225 (BFO62_00140) - 32793..34006 (+) 1214 Protein_28 replication initiation factor domain-containing protein -
  BFO62_RS00230 (BFO62_00145) - 34018..34329 (+) 312 WP_025458703.1 hypothetical protein -
  BFO62_RS00235 (BFO62_00150) - 34333..34533 (+) 201 WP_002212530.1 hypothetical protein -
  BFO62_RS00240 (BFO62_00155) - 34760..34990 (+) 231 WP_002216898.1 hypothetical protein -
  BFO62_RS00245 (BFO62_00160) - 35018..35317 (+) 300 WP_002216896.1 hypothetical protein -
  BFO62_RS00250 (BFO62_00165) - 35436..35651 (+) 216 Protein_33 DUF1132 family protein -

Sequence

Protein


Download         Length: 1007 a.a.        Molecular weight: 110967.04 Da        Isoelectric Point: 9.4860

>NTDB_id=167455 BFO62_RS00195 WP_025458702.1 28120..31143(+) (pilC) [Neisseria meningitidis strain COL-201504-11]
MNSQKLPEVKWGNSYKKGELRPEDRDRKFTFTSTYGIKRNTNITFNNTDYLVSEKNGTAVFGAATYLPPYGKVSGFDTDR
LTKRGNAVDWINTTHPGLIGYSYQGITCSSSSCPEFGYKTQFTFGNSGLAKKTNSSKLDIYEDKSRDNSPIYKLQDYPWL
GVSFNLSSDSYVKQKRHNSLVSSFSEDVTQSNGTQSPYKDRNLVYRTDDYHNKGNYSHQDAHHAIAFYLNAKLHLLDKKQ
IKNIAQGSELNLGMLKTHIELPKNFNQRSLVGSVVSWTVKDEGKVSVKLKLPEVKAGRCINKDNPNPKSKAPSPALTAPA
LWFGPVQNGKAQMYSASVSTYPDSSSSRIFLQNLERKTDPGRPGRHSLETLTENDIKSRQPNFTGRQTIIRLDSGVQQIK
LDQNNTEVVNFNGNSNNATFGIVSEYGLTPDANEWKKVLLPWTVRAFNDDGRFNTVNKEENNGKPKYSQKYRSRDNGKHE
RNLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRKDIQNTESTLAKELRAFAEKSYVGDRY
GVDGGFVLRKVERNGKDHVFMFGAMGFGGRGAYALDLSKIDSGNGNLADVSLFDVKHDKNDNNRVELGYTVGTPQIGKTH
DGKYAAFLASGYATKTIDDQQNKTALYVYDLESSGTLIKKIDVPGGKGGLSSPTLVDKDLDGIVDIAYAGDRGGNMYRFD
LSSDNPSSWTVRTIFSGNKPITSAPAISQLKDKRVVIFGTGSDLSEDDVDKTDEQYIYGIFDDDTATTGPVNFSGTGGGL
LEQVLTEENKTLFLTDYKRSDGSGSKGWVVKLKDGQRVTVKPTVVLRTAFVTIRKYKDNGCGAETAILGINTADGGKLTK
KSARPIVPADNTAVAQYSGHKQTTKGKSIPIGCMEKDNGIVCPNGYVYDKPVNVRYLDEKKTDGFSTTADGDAGGSGIDP
DGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3024 bp        

>NTDB_id=167455 BFO62_RS00195 WP_025458702.1 28120..31143(+) (pilC) [Neisseria meningitidis strain COL-201504-11]
ATGAACAGTCAAAAGCTGCCCGAGGTAAAGTGGGGGAATTCATATAAAAAAGGGGAGTTGAGGCCCGAAGACAGGGATCG
TAAATTTACCTTTACGAGTACTTATGGAATCAAACGCAACACTAATATCACATTCAATAATACCGATTATCTTGTTTCTG
AAAAAAACGGTACTGCCGTTTTCGGCGCGGCGACCTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATACCGATAGG
CTGACCAAGCGCGGCAATGCCGTTGATTGGATTAATACGACCCACCCGGGGTTGATAGGCTACAGCTACCAAGGTATCAC
ATGCAGCAGCAGCAGCTGTCCTGAATTTGGCTATAAAACCCAATTTACCTTCGGTAATTCCGGTTTGGCAAAAAAGACAA
ACAGCAGCAAGCTGGATATATACGAAGACAAAAGCCGCGACAATTCGCCCATTTACAAATTGCAGGATTATCCTTGGTTG
GGCGTGTCTTTCAATTTGAGCAGCGATAGCTACGTCAAACAAAAGAGACACAATAGTTTGGTATCTTCTTTTAGCGAGGA
TGTGACGCAGAGCAATGGTACGCAAAGCCCATACAAAGACAGAAACCTCGTTTATCGTACAGACGATTACCATAATAAGG
GTAATTATAGCCATCAGGACGCACACCACGCCATCGCCTTTTATCTGAACGCCAAGCTGCACCTGCTGGATAAAAAACAA
ATCAAAAATATCGCGCAAGGCAGTGAACTTAATTTGGGTATGTTGAAAACGCACATCGAGCTGCCGAAAAATTTTAATCA
AAGGAGCTTGGTAGGTTCGGTGGTTAGTTGGACGGTTAAAGATGAGGGAAAAGTCAGCGTCAAACTCAAATTGCCGGAAG
TCAAAGCAGGCCGCTGCATCAACAAAGATAACCCCAATCCCAAATCCAAAGCCCCTTCCCCCGCCCTGACCGCCCCCGCG
CTGTGGTTCGGACCTGTGCAAAATGGTAAGGCGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAG
CCGCATCTTCCTTCAAAATCTGGAAAGAAAAACCGACCCCGGCAGACCCGGCCGCCATTCCCTCGAAACCTTGACTGAGA
ACGATATTAAAAGTCGACAGCCGAATTTCACAGGGCGGCAAACAATCATCCGATTGGATAGCGGCGTACAGCAGATTAAA
CTGGATCAAAACAATACTGAGGTCGTCAATTTTAATGGAAACAGCAACAACGCAACTTTCGGCATTGTTAGTGAATATGG
CCTCACGCCTGATGCCAATGAGTGGAAAAAAGTATTGCTGCCTTGGACGGTTCGTGCTTTCAATGATGACGGTCGATTTA
ACACAGTCAACAAAGAAGAAAACAACGGCAAGCCAAAATACAGTCAAAAATACCGCAGCCGCGACAACGGCAAGCACGAG
CGCAATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGT
GCATATCTTCAAACAAAGCGGCGGGGACAAGCGCAGCTACAATCTGAAGCTCAGTTATATCCCGGGTACGATGCCGCGCA
AGGATATTCAAAACACCGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAAGCTATGTGGGCGACCGCTAC
GGCGTGGACGGCGGCTTTGTCTTGCGCAAAGTCGAACGGAACGGGAAAGACCATGTGTTTATGTTCGGCGCGATGGGCTT
TGGCGGCAGAGGCGCGTATGCCTTGGATTTAAGCAAAATCGACAGCGGCAACGGCAACCTGGCAGACGTTTCCCTGTTTG
ATGTCAAACATGACAAGAATGACAATAATCGCGTGGAATTAGGCTACACCGTCGGCACACCGCAAATCGGCAAAACCCAC
GACGGCAAATACGCCGCTTTCCTCGCCTCCGGTTATGCGACTAAAACCATTGACGACCAACAAAATAAAACCGCGCTGTA
TGTGTATGATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTTCGTCCCCCA
CGCTGGTGGATAAAGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCGCTTTGAT
TTGAGCAGCGACAATCCGTCCAGCTGGACTGTACGCACTATTTTCAGCGGCAACAAACCGATTACTTCCGCGCCCGCCAT
TTCCCAACTGAAAGACAAACGCGTGGTTATCTTCGGCACGGGCAGCGATTTGAGTGAGGATGATGTTGATAAAACGGACG
AACAATATATTTACGGTATCTTTGACGACGATACGGCGACGACGGGTCCTGTAAACTTCAGCGGTACGGGAGGCGGGCTG
CTCGAGCAAGTGCTTACTGAGGAAAATAAAACCTTATTCCTGACCGATTACAAGCGATCCGACGGCTCGGGCAGCAAAGG
GTGGGTAGTGAAATTGAAGGACGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCC
GCAAATATAAAGACAACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAG
AAAAGCGCGCGCCCGATTGTGCCGGCCGACAATACGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCACCAAAGGCAA
ATCCATCCCTATAGGTTGTATGGAAAAAGACAATGGAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATG
TGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCC
GACGGCAAGCGTTCCGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAG
CTTGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterProScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(483-815)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

73.969

100

0.748

Multiple sequence alignment