Detailed information NTG0167413

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AL501_RS04370
• Genome accession: NZ_CP014023
• Coordinates: 883327..884370 (-)
• Length: 347 a.a.
• NCBI ID: WP_002461334.1
• Uniprot ID: A0A853V5Y6
• Organism: Staphylococcus lugdunensis strain FDAARGOS_143
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 878327..889370

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AL501_RS04340 (AL501_04275)	-	878748..879929 (-)	1182	WP_207754594.1	aminopeptidase	-
AL501_RS04345 (AL501_04280)	-	879999..880184 (-)	186	WP_002492715.1	DUF1128 domain-containing protein	-
AL501_RS04350 (AL501_04285)	-	880348..880812 (+)	465	WP_002477961.1	low molecular weight protein-tyrosine-phosphatase	-
AL501_RS04355 (AL501_04290)	-	880819..881103 (+)	285	WP_002461330.1	YtxH domain-containing protein	-
AL501_RS04360 (AL501_04295)	-	881306..882535 (+)	1230	WP_002461332.1	YihY/virulence factor BrkB family protein	-
AL501_RS04365 (AL501_04300)	vraR	882708..883337 (-)	630	WP_002461333.1	two-component system response regulator VraR	Regulator
AL501_RS04370 (AL501_04305)	vraS	883327..884370 (-)	1044	WP_002461334.1	sensor histidine kinase	Regulator
AL501_RS04375 (AL501_04310)	liaF	884367..885068 (-)	702	WP_002461335.1	cell wall-active antibiotics response protein LiaF	-
AL501_RS04380 (AL501_04315)	-	885093..885479 (-)	387	WP_002477960.1	hypothetical protein	-
AL501_RS04385 (AL501_04320)	map	885605..886360 (-)	756	WP_002461338.1	type I methionyl aminopeptidase	-
AL501_RS04390 (AL501_04325)	-	886605..887585 (+)	981	WP_002492696.1	FUSC family protein	-
AL501_RS04395 (AL501_04330)	-	887719..889080 (+)	1362	WP_002477958.1	FAD-dependent oxidoreductase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39934.41 Da
• Isoelectric Point: 5.9679

>NTDB_id=167413 AL501_RS04370 WP_002461334.1 883327..884370(-) (vraS) [Staphylococcus lugdunensis strain FDAARGOS_143]
MNHYIRAIGSMLILVYSLMIAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSILAFKINQQNDWIKT
QVEHAIEGETVGINDQNIELYNETIDLYHTLVPLNQELHRLRMKTQNLTNENYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHDI
EEFKVPKGLEDHLFRITQEAISNTLRHSKGTKVTVELFNKADYLLLRIQDNGIGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=167413 AL501_RS04370 WP_002461334.1 883327..884370(-) (vraS) [Staphylococcus lugdunensis strain FDAARGOS_143]
ATGAACCACTATATTCGAGCAATCGGCTCAATGTTGATACTAGTGTATAGCTTAATGATTGCTTTTCTGTTTATTGATAA
AGTATTCGTTAATATCATTTACTTTCAAGGCATGTTTTATACACAAATATTTGGAATACCAGTATTCCTTTTCTTAAATT
TGGTTATTATTTTATTATGTATTATTGTGGGCTCTATATTAGCTTTTAAAATCAATCAACAAAATGATTGGATCAAAACA
CAAGTAGAGCATGCAATAGAAGGGGAAACAGTTGGTATAAATGATCAAAATATAGAATTGTATAATGAAACAATTGATTT
ATATCATACATTAGTTCCCTTAAATCAAGAGTTACACCGATTAAGAATGAAAACACAAAACTTAACAAATGAAAATTATA
ATTTAAATGATGTAAAAGTGAAAAAAATAATTGAAGACGAACGTCAACGTCTAGCTCGAGAATTACATGATTCAGTGAGC
CAGCAATTATTTGCAGCCAGTATGATGTTATCTGCAATTAAAGAAACAGAGCTAGAACCACCTTTAGATCAACAAATTCC
AGTTTTAGAAAAAATGGTGCAAGATTCACAACTTGAAATGAGAGCACTCTTATTACATCTAAGACCAATTGGTTTAAAGG
ACAAGTCGTTGGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAGAAAAAAGTACCGATGAAAGTGGTTCACGATATT
GAAGAATTTAAAGTGCCTAAAGGTTTAGAAGATCATTTGTTTAGAATTACTCAAGAAGCCATCTCTAATACTTTAAGACA
TTCAAAAGGAACTAAAGTTACTGTAGAATTATTTAATAAAGCAGATTATTTATTATTAAGAATACAAGATAATGGCATTG
GATTTAATGTTGATGATAAAGTCGAACAAAGTTATGGCTTGAAAAATATGCGCGAACGTGCGTTAGAAATAGGTGCAACA
TTTCATATTGTATCATTGCCTGATTCTGGAACAAGAATAGAGGTTAAAGCACCGTTAAACAAGGAGGATTCACATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A853V5Y6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	91.066	100	0.911