Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ASL17_RS11430 Genome accession   NZ_CP013957
Coordinates   2216829..2217608 (+) Length   259 a.a.
NCBI ID   WP_000688495.1    Uniprot ID   -
Organism   Staphylococcus aureus strain V521 isolate Sequencing     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2211829..2222608
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ASL17_RS11400 (ASL17_11405) - 2212048..2212674 (+) 627 WP_000522384.1 nitroreductase family protein -
  ASL17_RS11405 (ASL17_11410) - 2213035..2213820 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  ASL17_RS17545 hld 2214417..2214497 (-) 81 WP_000046022.1 delta-hemolysin -
  ASL17_RS11415 (ASL17_11420) agrB 2214787..2215356 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  ASL17_RS11420 (ASL17_11425) agrD 2215353..2215493 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ASL17_RS11425 (ASL17_11430) agrC 2215518..2216810 (+) 1293 WP_014532426.1 quorum-sensing sensor histidine kinase AgrC -
  ASL17_RS11430 (ASL17_11435) agrA 2216829..2217608 (+) 780 WP_000688495.1 quorum-sensing response regulator AgrA Regulator
  ASL17_RS11435 (ASL17_11440) - 2217616..2217723 (+) 108 WP_001790167.1 hypothetical protein -
  ASL17_RS11440 (ASL17_11445) - 2217911..2218870 (-) 960 WP_001253313.1 carbohydrate kinase family protein -
  ASL17_RS11445 (ASL17_11450) - 2218867..2220351 (-) 1485 WP_000141417.1 sucrose-6-phosphate hydrolase -
  ASL17_RS11450 (ASL17_11455) - 2220500..2221450 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 30361.82 Da        Isoelectric Point: 6.8880

>NTDB_id=166675 ASL17_RS11430 WP_000688495.1 2216829..2217608(+) (agrA) [Staphylococcus aureus strain V521 isolate Sequencing]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKYNK
IIKSVNGVFNCKSCWILTR

Nucleotide


Download         Length: 780 bp        

>NTDB_id=166675 ASL17_RS11430 WP_000688495.1 2216829..2217608(+) (agrA) [Staphylococcus aureus strain V521 isolate Sequencing]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAATATAATAAG
ATAATAAAGTCAGTTAACGGCGTATTCAATTGTAAATCTTGTTGGATTTTAACAAGATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-242)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

91.506

0.915

Multiple sequence alignment