Detailed information NTG0166605

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ASL15_RS04985
• Genome accession: NZ_CP013955
• Coordinates: 1022187..1023173 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain NCCP14562 isolate Sequencing
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1017187..1028173

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ASL15_RS04960 (ASL15_04965)	opp4B	1017401..1018363 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ASL15_RS04965 (ASL15_04970)	opp4C	1018375..1019256 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
ASL15_RS04970 (ASL15_04975)	trpS	1019298..1020287 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ASL15_RS04975 (ASL15_04980)	spxA	1020581..1020976 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ASL15_RS04980 (ASL15_04985)	mecA	1021347..1022066 (+)	720	WP_001217728.1	adaptor protein MecA	-
ASL15_RS04985 (ASL15_04990)	coiA	1022187..1023173 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ASL15_RS04990 (ASL15_04995)	pepF	1023221..1025029 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
ASL15_RS04995 (ASL15_05000)	yjbH	1025489..1026295 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ASL15_RS05000 (ASL15_05005)	-	1026318..1026683 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ASL15_RS05005 (ASL15_05010)	-	1026787..1027380 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ASL15_RS05010 (ASL15_05015)	-	1027566..1027913 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=166605 ASL15_RS04985 WP_000959282.1 1022187..1023173(+) (coiA) [Staphylococcus aureus strain NCCP14562 isolate Sequencing]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=166605 ASL15_RS04985 WP_000959282.1 1022187..1023173(+) (coiA) [Staphylococcus aureus strain NCCP14562 isolate Sequencing]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976