Detailed information NTG0166591

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ASL16_RS14635
• Genome accession: NZ_CP013953
• Coordinates: 2853673..2854560 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain NCCP14558 isolate sequencing
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2848673..2859560

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ASL16_RS14600 (ASL16_14605)	-	2848692..2848784 (+)	93	WP_010956583.1	hypothetical protein	-
ASL16_RS14605 (ASL16_14610)	-	2848892..2849389 (-)	498	WP_001065268.1	glutathione peroxidase	-
ASL16_RS14610 (ASL16_14615)	-	2849399..2849659 (-)	261	WP_001791974.1	hypothetical protein	-
ASL16_RS14615 (ASL16_14620)	-	2850041..2850154 (-)	114	Protein_2795	hypothetical protein	-
ASL16_RS14625 (ASL16_14630)	-	2850813..2852813 (-)	2001	WP_000776751.1	ABC transporter permease	-
ASL16_RS14630 (ASL16_14635)	-	2852810..2853565 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ASL16_RS14635 (ASL16_14640)	braS	2853673..2854560 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ASL16_RS14640 (ASL16_14645)	braR	2854571..2855236 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ASL16_RS14645 (ASL16_14650)	-	2855262..2855462 (-)	201	WP_000604730.1	hypothetical protein	-
ASL16_RS14655 (ASL16_14660)	-	2855660..2857084 (+)	1425	WP_000953755.1	alkaline phosphatase	-
ASL16_RS16570	-	2857144..2857245 (-)	102	WP_000731976.1	SE2200 family small protein	-
ASL16_RS14660 (ASL16_14665)	-	2857367..2857822 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ASL16_RS14665 (ASL16_14670)	-	2858067..2858828 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=166591 ASL16_RS14635 WP_000143425.1 2853673..2854560(-) (braS) [Staphylococcus aureus strain NCCP14558 isolate sequencing]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=166591 ASL16_RS14635 WP_000143425.1 2853673..2854560(-) (braS) [Staphylococcus aureus strain NCCP14558 isolate sequencing]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1