Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ASL16_RS11385 Genome accession   NZ_CP013953
Coordinates   2227752..2228468 (+) Length   238 a.a.
NCBI ID   WP_063663582.1    Uniprot ID   D5LFT2
Organism   Staphylococcus aureus strain NCCP14558 isolate sequencing     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2222752..2233468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ASL16_RS11355 (ASL16_11360) - 2222968..2223595 (+) 628 Protein_2170 nitroreductase family protein -
  ASL16_RS11360 (ASL16_11365) - 2223956..2224741 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  ASL16_RS16545 hld 2225341..2225421 (-) 81 WP_000046022.1 delta-hemolysin -
  ASL16_RS11370 (ASL16_11375) - 2225711..2226274 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  ASL16_RS11375 (ASL16_11380) agrD 2226277..2226420 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  ASL16_RS11380 (ASL16_11385) agrC 2226450..2227733 (+) 1284 WP_042109531.1 quorum-sensing sensor histidine kinase AgrC -
  ASL16_RS11385 (ASL16_11390) agrA 2227752..2228468 (+) 717 WP_063663582.1 quorum-sensing response regulator AgrA Regulator
  ASL16_RS11390 (ASL16_11395) - 2228540..2228649 (+) 110 Protein_2177 hypothetical protein -
  ASL16_RS11395 (ASL16_11400) - 2228837..2229796 (-) 960 WP_001253312.1 carbohydrate kinase family protein -
  ASL16_RS11400 (ASL16_11405) - 2229793..2231277 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  ASL16_RS11405 (ASL16_11410) - 2231426..2232376 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27847.86 Da        Isoelectric Point: 6.3001

>NTDB_id=166587 ASL16_RS11385 WP_063663582.1 2227752..2228468(+) (agrA) [Staphylococcus aureus strain NCCP14558 isolate sequencing]
MKIFICEGDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=166587 ASL16_RS11385 WP_063663582.1 2227752..2228468(+) (agrA) [Staphylococcus aureus strain NCCP14558 isolate sequencing]
ATGAAAATTTTCATTTGCGAAGGCGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D5LFT2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment