Detailed information NTG0166586

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ASL16_RS10880
• Genome accession: NZ_CP013953
• Coordinates: 2133776..2134819 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain NCCP14558 isolate sequencing
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2128776..2139819

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ASL16_RS10850 (ASL16_10855)	-	2129197..2130453 (-)	1257	WP_001795108.1	aminopeptidase	-
ASL16_RS10855 (ASL16_10860)	-	2130456..2130656 (-)	201	WP_000180460.1	DUF1128 family protein	-
ASL16_RS10860 (ASL16_10865)	-	2130803..2131267 (+)	465	WP_042109418.1	low molecular weight protein-tyrosine-phosphatase	-
ASL16_RS10865 (ASL16_10870)	-	2131274..2131549 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ASL16_RS10870 (ASL16_10875)	-	2131827..2133044 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
ASL16_RS10875 (ASL16_10880)	vraR	2133157..2133786 (-)	630	WP_042109421.1	two-component system response regulator VraR	Regulator
ASL16_RS10880 (ASL16_10885)	vraS	2133776..2134819 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ASL16_RS10885 (ASL16_10890)	liaF	2134816..2135517 (-)	702	WP_063663545.1	cell wall-active antibiotics response protein LiaF	-
ASL16_RS10890 (ASL16_10895)	-	2135532..2135918 (-)	387	WP_001110179.1	hypothetical protein	-
ASL16_RS10895 (ASL16_10900)	map	2136135..2136893 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ASL16_RS16110	-	2137424..2137552 (+)	129	WP_256969316.1	aromatic acid exporter family protein	-
ASL16_RS10905 (ASL16_10910)	-	2137642..2138961 (+)	1320	WP_001557163.1	ISL3-like element IS1181 family transposase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=166586 ASL16_RS10880 WP_001017131.1 2133776..2134819(-) (vraS) [Staphylococcus aureus strain NCCP14558 isolate sequencing]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=166586 ASL16_RS10880 WP_001017131.1 2133776..2134819(-) (vraS) [Staphylococcus aureus strain NCCP14558 isolate sequencing]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1