Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | ASL16_RS00290 | Genome accession | NZ_CP013953 |
| Coordinates | 63174..64802 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain NCCP14558 isolate sequencing | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 57953..103009 | 63174..64802 | within | 0 |
| SCCmec | 44911..66173 | 63174..64802 | within | 0 |
Gene organization within MGE regions
Location: 44911..103009
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ASL16_RS00195 (ASL16_00195) | mecA | 44911..46920 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| ASL16_RS00200 (ASL16_00200) | mecR1 | 47017..48774 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| ASL16_RS00205 (ASL16_00205) | mecI | 48774..49145 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| ASL16_RS15950 | psm-mec | 49230..49298 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| ASL16_RS00210 (ASL16_00210) | - | 49632..50762 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| ASL16_RS00220 (ASL16_00220) | cstB | 50876..52210 (-) | 1335 | Protein_40 | persulfide dioxygenase-sulfurtransferase CstB | - |
| ASL16_RS00225 (ASL16_00225) | - | 52243..53307 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| ASL16_RS00230 (ASL16_00230) | cstR | 53443..53703 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| ASL16_RS00235 (ASL16_00235) | - | 53703..54341 (+) | 639 | Protein_43 | sulfite exporter TauE/SafE family protein | - |
| ASL16_RS16520 | - | 54395..54454 (-) | 60 | Protein_44 | DNA repair protein RadC | - |
| ASL16_RS00240 (ASL16_00240) | - | 54686..55348 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| ASL16_RS00245 (ASL16_00245) | erm(A) | 55779..56510 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| ASL16_RS00250 (ASL16_00250) | - | 56636..57418 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| ASL16_RS00255 (ASL16_00255) | - | 57569..57946 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| ASL16_RS00260 (ASL16_00260) | - | 57953..59845 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| ASL16_RS00265 (ASL16_00265) | - | 59842..60927 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| ASL16_RS00270 (ASL16_00270) | - | 61046..61363 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| ASL16_RS00275 (ASL16_00275) | - | 61384..61890 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| ASL16_RS00280 (ASL16_00280) | - | 61908..62219 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| ASL16_RS00285 (ASL16_00285) | - | 62306..62656 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| ASL16_RS00290 (ASL16_00290) | ccrB | 63174..64802 (-) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| ASL16_RS00295 (ASL16_00295) | ccrA | 64824..66173 (-) | 1350 | WP_000815646.1 | cassette chromosome recombinase CcrA | Machinery gene |
| ASL16_RS00300 (ASL16_00300) | cch1 | 66407..68200 (-) | 1794 | WP_000195100.1 | cassette chromosome replicative helicase | - |
| ASL16_RS00305 (ASL16_00305) | ssb | 68200..68496 (-) | 297 | WP_000273824.1 | cassette chromosome ssDNA-binding protein | - |
| ASL16_RS00310 (ASL16_00310) | - | 68689..69735 (-) | 1047 | WP_001060127.1 | hypothetical protein | - |
| ASL16_RS15255 | - | 69986..71127 (-) | 1142 | Protein_60 | IS3-like element ISSau4 family transposase | - |
| ASL16_RS00330 (ASL16_00330) | - | 71638..72573 (-) | 936 | Protein_61 | YfcC family protein | - |
| ASL16_RS00335 (ASL16_00335) | - | 72788..73960 (-) | 1173 | WP_000195429.1 | IS256-like element IS256 family transposase | - |
| ASL16_RS00340 (ASL16_00340) | - | 74618..75313 (-) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| ASL16_RS00345 (ASL16_00345) | - | 75288..77957 (-) | 2670 | WP_000446429.1 | sensor histidine kinase | - |
| ASL16_RS00350 (ASL16_00350) | kdpF | 78124..78204 (+) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| ASL16_RS00355 (ASL16_00355) | kdpA | 78225..79901 (+) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| ASL16_RS00360 (ASL16_00360) | - | 79920..81941 (+) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| ASL16_RS00365 (ASL16_00365) | - | 81957..82514 (+) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| ASL16_RS00370 (ASL16_00370) | - | 83059..83928 (-) | 870 | WP_000626133.1 | hypothetical protein | - |
| ASL16_RS00375 (ASL16_00375) | - | 83938..84834 (-) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| ASL16_RS00385 (ASL16_00385) | - | 85953..86579 (-) | 627 | WP_001176969.1 | hypothetical protein | - |
| ASL16_RS00390 (ASL16_00390) | - | 86694..88202 (+) | 1509 | WP_001001347.1 | protein kinase domain-containing protein | - |
| ASL16_RS00395 (ASL16_00395) | - | 88452..88586 (-) | 135 | WP_001790628.1 | hypothetical protein | - |
| ASL16_RS00400 (ASL16_00400) | - | 88550..88642 (+) | 93 | WP_001790000.1 | hypothetical protein | - |
| ASL16_RS00405 (ASL16_00405) | - | 88789..90534 (+) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| ASL16_RS00410 (ASL16_00410) | - | 90632..90987 (-) | 356 | Protein_76 | tRNA-dihydrouridine synthase | - |
| ASL16_RS00415 (ASL16_00415) | - | 91292..91380 (-) | 89 | Protein_77 | hypothetical protein | - |
| ASL16_RS00420 (ASL16_00420) | - | 91478..92233 (-) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| ASL16_RS00425 (ASL16_00425) | cstR | 92233..92493 (-) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| ASL16_RS00430 (ASL16_00430) | cstA | 92630..93694 (+) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| ASL16_RS00435 (ASL16_00435) | cstB | 93725..95059 (+) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| ASL16_RS00440 (ASL16_00440) | sqr | 95078..96271 (+) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| ASL16_RS00455 (ASL16_00455) | - | 96937..97923 (-) | 987 | WP_000662022.1 | tRNA dihydrouridine synthase | - |
| ASL16_RS00460 (ASL16_00460) | - | 98232..98435 (+) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| ASL16_RS00465 (ASL16_00465) | - | 98484..98780 (+) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| ASL16_RS00470 (ASL16_00470) | - | 98988..99590 (+) | 603 | WP_000908956.1 | hypothetical protein | - |
| ASL16_RS00475 (ASL16_00475) | - | 99857..103009 (+) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=166551 ASL16_RS00290 WP_001186602.1 63174..64802(-) (ccrB) [Staphylococcus aureus strain NCCP14558 isolate sequencing]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=166551 ASL16_RS00290 WP_001186602.1 63174..64802(-) (ccrB) [Staphylococcus aureus strain NCCP14558 isolate sequencing]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |