Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | SE1UMMC_RS13460 | Genome accession | NZ_CP013943 |
| Coordinates | 2668544..2669890 (+) | Length | 448 a.a. |
| NCBI ID | WP_000816499.1 | Uniprot ID | Q9R3W9 |
| Organism | Staphylococcus epidermidis strain DAR1907 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 2642350..2689703 | 2668544..2669890 | within | 0 |
Gene organization within MGE regions
Location: 2642350..2689703
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SE1UMMC_RS13350 (SE1UMMC_12715) | ccrC | 2642350..2644035 (-) | 1686 | WP_032603677.1 | cassette chromosome recombinase CcrC | - |
| SE1UMMC_RS13355 (SE1UMMC_12720) | - | 2644262..2645869 (-) | 1608 | WP_002504273.1 | DUF5906 domain-containing protein | - |
| SE1UMMC_RS13360 (SE1UMMC_12725) | - | 2645862..2646236 (-) | 375 | WP_002504272.1 | hypothetical protein | - |
| SE1UMMC_RS13365 (SE1UMMC_12730) | - | 2646226..2647362 (-) | 1137 | WP_002504271.1 | DNA polymerase | - |
| SE1UMMC_RS13370 (SE1UMMC_12735) | - | 2647451..2647804 (-) | 354 | WP_002504077.1 | hypothetical protein | - |
| SE1UMMC_RS13375 (SE1UMMC_12740) | - | 2648011..2649873 (-) | 1863 | WP_002504078.1 | DUF6038 family protein | - |
| SE1UMMC_RS13380 (SE1UMMC_12745) | - | 2650488..2653169 (+) | 2682 | WP_002484615.1 | MMPL family transporter | - |
| SE1UMMC_RS13385 (SE1UMMC_12750) | - | 2653193..2654137 (+) | 945 | WP_002484621.1 | glycine betaine ABC transporter substrate-binding protein | - |
| SE1UMMC_RS13390 (SE1UMMC_12755) | - | 2654487..2655056 (+) | 570 | WP_002504079.1 | TetR/AcrR family transcriptional regulator | - |
| SE1UMMC_RS13395 | - | 2655267..2655941 (+) | 675 | Protein_2519 | IS6 family transposase | - |
| SE1UMMC_RS13400 (SE1UMMC_12770) | lpdA | 2656158..2657579 (-) | 1422 | WP_002504088.1 | dihydrolipoyl dehydrogenase | - |
| SE1UMMC_RS13405 (SE1UMMC_12775) | - | 2657761..2660169 (-) | 2409 | WP_002504087.1 | heavy metal translocating P-type ATPase | - |
| SE1UMMC_RS13410 (SE1UMMC_12780) | - | 2660428..2661195 (-) | 768 | WP_002454666.1 | ZIP family metal transporter | - |
| SE1UMMC_RS13415 (SE1UMMC_12785) | - | 2661449..2661850 (-) | 402 | WP_002454665.1 | ArsR/SmtB family transcription factor | - |
| SE1UMMC_RS13420 (SE1UMMC_12790) | lspA | 2662012..2662464 (+) | 453 | WP_161799966.1 | signal peptidase II | - |
| SE1UMMC_RS13425 | - | 2662492..2663166 (-) | 675 | Protein_2525 | IS6 family transposase | - |
| SE1UMMC_RS13430 | - | 2663356..2663879 (+) | 524 | Protein_2526 | transposase | - |
| SE1UMMC_RS13435 (SE1UMMC_12810) | - | 2664104..2664676 (-) | 573 | WP_000489177.1 | ADP-ribosyltransferase | - |
| SE1UMMC_RS13440 (SE1UMMC_12815) | - | 2664729..2665778 (-) | 1050 | WP_000613217.1 | hypothetical protein | - |
| SE1UMMC_RS13445 (SE1UMMC_12820) | ssb | 2665915..2666199 (+) | 285 | WP_000659554.1 | cassette chromosome ssDNA-binding protein | - |
| SE1UMMC_RS13450 (SE1UMMC_12825) | cch1 | 2666199..2667986 (+) | 1788 | WP_000181743.1 | cassette chromosome replicative helicase | - |
| SE1UMMC_RS13455 (SE1UMMC_12830) | - | 2668076..2668351 (+) | 276 | WP_001791132.1 | hypothetical protein | - |
| SE1UMMC_RS13460 (SE1UMMC_12835) | ccrA | 2668544..2669890 (+) | 1347 | WP_000816499.1 | cassette chromosome recombinase CcrA | Machinery gene |
| SE1UMMC_RS13465 (SE1UMMC_12840) | ccrB | 2669911..2671539 (+) | 1629 | WP_001186596.1 | cassette chromosome recombinase CcrB | Machinery gene |
| SE1UMMC_RS13470 (SE1UMMC_12845) | - | 2672010..2672360 (+) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| SE1UMMC_RS13480 (SE1UMMC_12850) | - | 2672445..2672756 (+) | 312 | WP_000833212.1 | DUF960 family protein | - |
| SE1UMMC_RS13485 (SE1UMMC_12855) | - | 2672775..2673296 (+) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| SE1UMMC_RS13490 (SE1UMMC_12860) | - | 2673298..2673504 (+) | 207 | WP_001077283.1 | hypothetical protein | - |
| SE1UMMC_RS13495 (SE1UMMC_12865) | - | 2673497..2673820 (+) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| SE1UMMC_RS13500 (SE1UMMC_12870) | - | 2674015..2675907 (+) | 1893 | WP_002485298.1 | site-specific integrase | - |
| SE1UMMC_RS13505 (SE1UMMC_12875) | - | 2675914..2676291 (+) | 378 | WP_064587220.1 | DUF6262 family protein | - |
| SE1UMMC_RS13510 (SE1UMMC_12880) | - | 2676529..2676894 (+) | 366 | WP_000159127.1 | ArsR/SmtB family transcription factor | - |
| SE1UMMC_RS13515 (SE1UMMC_12885) | - | 2676887..2679301 (+) | 2415 | WP_000378485.1 | cadmium-translocating P-type ATPase CadA | - |
| SE1UMMC_RS13520 (SE1UMMC_12890) | - | 2679382..2679999 (+) | 618 | WP_000562107.1 | CadD family cadmium resistance transporter | - |
| SE1UMMC_RS13530 (SE1UMMC_12895) | - | 2680273..2680911 (-) | 639 | Protein_2544 | sulfite exporter TauE/SafE family protein | - |
| SE1UMMC_RS13535 (SE1UMMC_12900) | cstR | 2680911..2681171 (-) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| SE1UMMC_RS13540 (SE1UMMC_12905) | - | 2681307..2682371 (+) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| SE1UMMC_RS13545 (SE1UMMC_12910) | cstB | 2682404..2683738 (+) | 1335 | Protein_2547 | persulfide dioxygenase-sulfurtransferase CstB | - |
| SE1UMMC_RS13555 (SE1UMMC_12920) | - | 2683852..2684982 (-) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| SE1UMMC_RS13880 | psm-mec | 2685316..2685384 (+) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| SE1UMMC_RS13565 (SE1UMMC_12925) | mecI | 2685469..2685840 (-) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| SE1UMMC_RS13570 (SE1UMMC_12930) | mecR1 | 2685840..2687597 (-) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| SE1UMMC_RS13575 (SE1UMMC_12935) | mecA | 2687694..2689703 (+) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
Sequence
Protein
Download Length: 448 a.a. Molecular weight: 52138.19 Da Isoelectric Point: 10.1760
>NTDB_id=166415 SE1UMMC_RS13460 WP_000816499.1 2668544..2669890(+) (ccrA) [Staphylococcus epidermidis strain DAR1907]
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
Nucleotide
Download Length: 1347 bp
>NTDB_id=166415 SE1UMMC_RS13460 WP_000816499.1 2668544..2669890(+) (ccrA) [Staphylococcus epidermidis strain DAR1907]
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
78.174 |
100 |
0.783 |
| ccrA | Staphylococcus aureus N315 |
72.383 |
100 |
0.725 |