Detailed information NTG0166327

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AVT04_RS04460
• Genome accession: NZ_CP013939
• Coordinates: 844068..846518 (-)
• Length: 816 a.a.
• NCBI ID: WP_011226754.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S9
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 839068..851518

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AVT04_RS04450 (AVT04_04450)	pbp3	841291..842538 (+)	1248	WP_041826942.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
AVT04_RS04455 (AVT04_04455)	pbp3	842708..843940 (+)	1233	Protein_842	D-alanyl-D-alanine carboxypeptidase PBP3	-
AVT04_RS04460 (AVT04_04460)	clpC	844068..846518 (-)	2451	WP_011226754.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
AVT04_RS04465 (AVT04_04465)	-	846519..846974 (-)	456	WP_011226753.1	CtsR family transcriptional regulator	-
AVT04_RS04470 (AVT04_04470)	-	847218..847688 (+)	471	WP_011225296.1	COG2426 family protein	-
AVT04_RS04475 (AVT04_04475)	tsf	847799..848839 (-)	1041	WP_002949105.1	translation elongation factor Ts	-
AVT04_RS04480 (AVT04_04480)	rpsB	848950..849717 (-)	768	WP_002944541.1	30S ribosomal protein S2	-
AVT04_RS09880	-	850240..851192 (+)	953	Protein_848	S66 family peptidase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90270.47 Da
• Isoelectric Point: 5.7956

>NTDB_id=166327 AVT04_RS04460 WP_011226754.1 844068..846518(-) (clpC) [Streptococcus thermophilus strain S9]
MTIYSRKMQAIFHRAQLEAERFESPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIHSEEIETAAVLAMEKRPKDLSESDI
IDLRAQSPALEAMLQEAQGIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERNAGLS
KQDLKAIHDLRKPKKSKASANFANMMQPPQSSTGELADYTKDLTALAESGNLDPVIGRDEEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVSEAIDILNGLRSSYEDYHRVTI
TDAAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQVRIKKEAKREITPLDEALISGDIGAAVKQYKANQKAKFPKPAL
VDADQIMQTLSRLSGIPVEKMTQTDSKRYLNLESELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEIEKAHPDIFNVL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAQTISHNHQAMQARIMEELKKSYRPEFINRIDEKVV
FHSLEEEQLHDIVKIMVKPLISALADKGISLKFQPAALKHLAKDGYDIEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=166327 AVT04_RS04460 WP_011226754.1 844068..846518(-) (clpC) [Streptococcus thermophilus strain S9]
ATGACGATATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAAGCGGAGCGTTTTGAAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTAGCTATGGTTGAGGTTCCGGGATCTGTAGCCTACTTAACATTTACTGATTTTGAGGACC
GTATTCATTCGGAAGAGATTGAGACAGCTGCTGTATTGGCTATGGAGAAGAGGCCAAAAGACTTGTCGGAATCAGATATT
ATCGATTTACGTGCACAGTCACCTGCGCTAGAGGCTATGTTGCAAGAGGCGCAAGGAATCGCTAGTGTGACTGGTGCTGT
AGAGGTGGGGTCTGAACATGTATTGATGGCCTTCCTTCTTCATAAGGATTTAATGGTTTGTCGCCTCCTTGAAGTGGCTG
GTTTTCAATATAAAGATGATAGCGATAAACCTCGCATCATAGATTTACGACGTTCTTTGGAGCGTAATGCTGGTCTTAGC
AAGCAAGATTTGAAGGCAATTCACGATCTTCGTAAACCTAAGAAATCAAAAGCATCTGCGAATTTTGCCAATATGATGCA
ACCTCCTCAATCATCTACTGGTGAACTGGCAGATTATACCAAAGACTTAACTGCATTAGCGGAGTCAGGAAATCTTGATC
CCGTTATTGGACGCGATGAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAATCCTGTCTTGGTA
GGTGAAGCTGGTGTCGGTAAGACAGCACTTGCTCTTGGTTTAGCGCAACGTATTGCTTCAGGCGAAGTACCATTTGAATT
GGCTGATATGCGTATCTTAGAGCTTGACATGATGAGCGTTGTTGCAGGGACACGTTTCCGTGGTGATTTCGAAGAACGTA
TGAATCAGATCATTGATGAGATTGAAGCTGATGGGAAAATCATTCTCTTTATTGACGAACTACATACGATTATTGGATCT
GGTTCAGGTATTGATAGTACCTTGGATGCGGCTAATATTTTGAAACCGGCCCTTGCGCGCGGGACACTTCACATGGTTGG
AGCAACCACGCAAGCTGAATACCAAAAGCATATTGAGAAAGATGCAGCTTTATCCCGTCGTTTTGCTAAAATTACAATTG
AAGAACCAAGTGTATCTGAAGCAATCGATATTTTAAACGGTTTGCGTTCGTCTTATGAAGACTATCATCGTGTGACTATT
ACGGACGCGGCAGTTGAGACGGCAGTCAAGGCAGCGCATCGCTATTTGACGAGTAAGAATTTGCCTGATTCGGCAATTGA
CCTTTTAGATGAAGCGAGTGCAACTGTTCAAGTTCGTATCAAAAAAGAGGCCAAACGTGAGATAACGCCTTTGGATGAAG
CACTTATATCTGGGGATATTGGGGCTGCTGTTAAACAGTATAAGGCTAACCAAAAGGCAAAATTTCCTAAACCTGCTTTG
GTAGATGCGGATCAGATTATGCAAACTCTTAGTCGTTTATCAGGTATCCCTGTTGAGAAGATGACGCAGACTGACAGCAA
GCGTTACCTGAATCTTGAATCAGAACTCCACAAACGTGTTATTGGTCAAGATGAGGCGGTTTCGGCTATCAGCCGTGCTA
TTCGTCGTAATCAGTCAGGTATTCGTACTGGAAAACGTCCTATTGGCTCCTTCATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAATTGGCCAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAATCAGCCTTGCTTCGCTTTGATATGTCGGAGTA
TATGGAAAAATTTGCGGCTAGTCGCCTTAATGGTGCTCCTCCAGGATATGTCGGATATGATGAGGGTGGAGAGTTGACAG
AGAAAGTTCGAAATAAGCCCTACTCAGTTCTTCTCTTTGACGAGATTGAGAAAGCTCATCCAGATATCTTCAACGTTCTC
TTACAGGTTTTGGATGACGGTGTTTTAACAGATAGCCGTGGTCGTAAGGTTGATTTTTCAAACACTATCATCATTATGAC
CTCAAATTTGGGAGCTACAGCTCTTCGTGATGATAAAACTGTTGGTTTTGGTGCTCAAACTATTTCTCATAATCACCAAG
CCATGCAAGCACGCATTATGGAAGAGCTTAAGAAGTCCTATCGTCCAGAATTTATTAACCGTATTGATGAGAAGGTTGTC
TTCCACAGCTTAGAGGAAGAACAACTACATGACATTGTCAAGATTATGGTTAAACCATTAATTTCAGCTCTAGCCGATAA
AGGTATAAGCTTAAAATTCCAACCAGCTGCTCTTAAGCATTTGGCTAAGGATGGCTATGATATTGAGATGGGAGCTCGTC
CATTACGTCGTACGATTCAAACTCAAGTGGAGGACAAGTTGTCTGAGTTATTACTAGGTGGCCAAGTTGTTAGCGGACAG
ACCCTTAAGATTGGTTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

• AAA lid domain (AAA_lid_9) (377-454)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (107-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	99.877	100	0.999
clpC	Streptococcus thermophilus LMD-9	99.51	100	0.995
clpC	Streptococcus mutans UA159	72.549	100	0.725
clpC	Streptococcus pneumoniae TIGR4	66.093	99.755	0.659
clpC	Streptococcus pneumoniae Rx1	66.093	99.755	0.659
clpC	Streptococcus pneumoniae D39	66.093	99.755	0.659
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.421	100	0.513
clpC	Bacillus subtilis subsp. subtilis str. 168	46.529	100	0.468
clpE	Streptococcus mutans UA159	47.604	76.716	0.365