Detailed information NTG0166064

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: A7J08_RS09875
• Genome accession: NZ_CP017088
• Coordinates: 1980849..1983389 (-)
• Length: 846 a.a.
• NCBI ID: WP_044679515.1
• Uniprot ID: -
• Organism: Streptococcus suis strain SRD478
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1975849..1988389

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7J08_RS10705 (A7J08_09600)	-	1977091..1977225 (-)	135	WP_002939130.1	hypothetical protein	-
A7J08_RS09855 (A7J08_09605)	nrdD	1977318..1979489 (-)	2172	WP_148115862.1	anaerobic ribonucleoside-triphosphate reductase	-
A7J08_RS09860 (A7J08_09610)	-	1979630..1979803 (-)	174	WP_002941962.1	hypothetical protein	-
A7J08_RS09865 (A7J08_09615)	-	1979837..1980277 (-)	441	WP_029752785.1	DUF3021 domain-containing protein	-
A7J08_RS09870 (A7J08_09620)	-	1980274..1980717 (-)	444	WP_044679516.1	LytTR family DNA-binding domain-containing protein	-
A7J08_RS09875 (A7J08_09625)	hexA	1980849..1983389 (-)	2541	WP_044679515.1	DNA mismatch repair protein MutS	Machinery gene
A7J08_RS09880 (A7J08_09630)	argR	1983404..1983844 (-)	441	WP_002937036.1	arginine repressor	-
A7J08_RS09885 (A7J08_09635)	argS	1983951..1985639 (+)	1689	WP_053867514.1	arginine--tRNA ligase	-
A7J08_RS09890 (A7J08_09640)	-	1985818..1986732 (+)	915	WP_053866789.1	SH3 domain-containing protein	-
A7J08_RS09895 (A7J08_09645)	-	1986786..1987310 (-)	525	WP_053866788.1	hypothetical protein	-
A7J08_RS09900 (A7J08_09650)	-	1987422..1987604 (+)	183	WP_002937045.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95017.59 Da
• Isoelectric Point: 4.8259

>NTDB_id=166064 A7J08_RS09875 WP_044679515.1 1980849..1983389(-) (hexA) [Streptococcus suis strain SRD478]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRIWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILLQINEPALGNLVAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLERADRILQTLENQAPTAPAKPAPSVV
AEPSGQIDLFADTPSHPVLDELEKLDIYNMTPMEVMMAVAELKKKL

Nucleotide

• Length: 2541 bp

>NTDB_id=166064 A7J08_RS09875 WP_044679515.1 1980849..1983389(-) (hexA) [Streptococcus suis strain SRD478]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAGTTATTTTATGAAGATGCGGTAGAAGCGGCGCAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAGAATCCGATTCCAATGGCGGGGGTACCGTATCACGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
ACAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAGATCCGCAATTTACGGGCACGTGAATTGGTCATCGGCTATGCTTTATCTGAGGAAGAAGAGCAGGTCTT
TTCGAACCAGATGAACCTCCTACTCTCTTTTGAAGATGAGGTGACAGAGGATGTCCAGCTGATTGACAATTCGCTGACAG
ATTTGGAAAAGGCTGCGGCGGGCAAACTCCTCAGCTACCTTCATCGGACTCAGATGCGGGATTTGAGTCACTTGCAAAAG
GTGGTCCACTATGAAATCAAGGACTATCTGCAAATGGACTATGCAACCAAGTCCAGTCTGGACCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGCTAGACGAAACCAAGACAGCCATGGGTATGCGACTATTGCGGATAT
GGATTGATCGTCCCTTGATTGACCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTCGAGGCTTTAAAAGGTGTCTATGACATCGAACGCTTGGCCAGTCGGGTGTCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCCCAGACTTTGGGAAATATCCCAGCAATCAAGAATATCTTGCTACAAATCAATG
AGCCTGCTCTAGGCAATCTGGTAGCTGGATTGGACCCAATTCCAGAACTGCACGCTCTCATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACTATCACAGATGGAAACATCATCCGTACAGGCTTTGACGAAACGCTGGATCAGTACCGTCTGGTCAT
GCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCTAAGGAGCGTGAAGCGTCTGGTATCAACAATCTCAAGATTGATT
ACAACAAAAAAGACGGCTACTATTTCCATGTGACCAATTCCAATCTGGGCAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGCTATGGAACGGAAGAGTTGGCTAAGATCGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATCGGTCGCTTGCAGAAGTTGGCTC
GGACCATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTTACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACTTGAATACCGATACACATATGCAACTGATTACTGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGGC
AGTTGGCGGTAATCGTCATCATGGCGCAGATGGGTTCCTATGTACCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACCCGAATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTCATGGTCGAAATGATGGAGGCCAATAA
GGCGGTCCGTCTGGCGACAGATCGGTCGCTCATCCTCTTTGATGAGTTGGGACGGGGAACGGCCACCTATGACGGTATGG
CCCTGGCCCAGTCTATCATCGAGTACATCCATGACAAGATTGGTGCCAAGACTCTCTTTGCCACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACTTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGCCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAGTTAT
TGGAGCGAGCGGATAGGATTTTGCAGACACTTGAAAATCAAGCCCCTACTGCACCAGCAAAACCAGCTCCATCAGTGGTG
GCAGAACCGTCTGGTCAAATCGACCTCTTTGCAGACACACCTTCTCACCCAGTCCTCGATGAACTGGAGAAACTGGACAT
CTACAATATGACCCCAATGGAAGTCATGATGGCTGTGGCAGAATTGAAGAAGAAATTATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.113	100	0.741
mutS	Pseudomonas stutzeri strain ATCC 17587	37.398	100	0.381