Detailed information NTG0165133

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: MGAS27061_RS06485
• Genome accession: NZ_CP013840
• Coordinates: 1331265..1331990 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain MGAS27061
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1326265..1336990

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS27061_RS06450 (MGAS27061_1324)	rnpM	1326299..1326595 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
MGAS27061_RS06455 (MGAS27061_1325)	nusA	1326611..1327768 (-)	1158	WP_002983485.1	transcription termination factor NusA	-
MGAS27061_RS06460 (MGAS27061_1326)	rimP	1327943..1328479 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
MGAS27061_RS06470 (MGAS27061_1328)	trmB	1328738..1329373 (-)	636	WP_031488472.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
MGAS27061_RS06475 (MGAS27061_1329)	ccrZ	1329373..1330164 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
MGAS27061_RS06480 (MGAS27061_1330)	-	1330228..1331262 (-)	1035	WP_031577431.1	ABC transporter permease	-
MGAS27061_RS06485 (MGAS27061_1331)	pptA	1331265..1331990 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
MGAS27061_RS06490 (MGAS27061_1332)	-	1332062..1332481 (+)	420	WP_002983376.1	HIT family protein	-
MGAS27061_RS06495 (MGAS27061_1333)	-	1332478..1332834 (+)	357	WP_031488470.1	hypothetical protein	-
MGAS27061_RS06500 (MGAS27061_1334)	brpA	1332945..1334228 (-)	1284	WP_031488469.1	biofilm formation/cell division transcriptional regulator BrpA	-
MGAS27061_RS06505 (MGAS27061_1335)	-	1334237..1334761 (-)	525	WP_031488468.1	GNAT family N-acetyltransferase	-
MGAS27061_RS06510 (MGAS27061_1336)	tsaE	1334736..1335197 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
MGAS27061_RS06515 (MGAS27061_1337)	-	1335351..1336811 (-)	1461	WP_031488467.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=165133 MGAS27061_RS06485 WP_002983379.1 1331265..1331990(-) (pptA) [Streptococcus pyogenes strain MGAS27061]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=165133 MGAS27061_RS06485 WP_002983379.1 1331265..1331990(-) (pptA) [Streptococcus pyogenes strain MGAS27061]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714