Detailed information NTG0164612

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: BE841_RS04280
• Genome accession: NZ_CP016868
• Coordinates: 993810..996386 (-)
• Length: 858 a.a.
• NCBI ID: WP_011215726.1
• Uniprot ID: -
• Organism: Legionella pneumophila subsp. pneumophila strain FFI102
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 988810..1001386

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BE841_RS04260 (BE841_04260)	-	989539..990087 (+)	549	WP_011215730.1	hypothetical protein	-
BE841_RS04265 (BE841_04265)	mpl	990089..991456 (+)	1368	WP_011215729.1	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase	-
BE841_RS04270 (BE841_04270)	-	991746..992393 (+)	648	WP_080020631.1	lpg1752 family Dot/Icm T4SS effector	-
BE841_RS04275 (BE841_04275)	-	992406..993719 (+)	1314	WP_011215727.1	lpg1751 family Dot/Icm T4SS effector	-
BE841_RS04280 (BE841_04280)	clpC	993810..996386 (-)	2577	WP_011215726.1	ATP-dependent chaperone ClpB	Regulator
BE841_RS04285 (BE841_04285)	-	996475..997431 (+)	957	WP_011215725.1	S49 family peptidase	-
BE841_RS04290 (BE841_04290)	-	997538..998323 (-)	786	WP_010947474.1	inositol monophosphatase family protein	-
BE841_RS04295 (BE841_04295)	trmJ	998439..999212 (+)	774	WP_011215724.1	tRNA (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ	-
BE841_RS04300 (BE841_04300)	-	999217..1000350 (+)	1134	WP_050901380.1	IscS subfamily cysteine desulfurase	-
BE841_RS04305 (BE841_04305)	-	1000347..1000730 (+)	384	WP_010947471.1	iron-sulfur cluster assembly scaffold protein	-
BE841_RS04310 (BE841_04310)	-	1000735..1001103 (+)	369	WP_011215722.1	HesB/IscA family protein	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 95778.59 Da
• Isoelectric Point: 5.3669

>NTDB_id=164612 BE841_RS04280 WP_011215726.1 993810..996386(-) (clpC) [Legionella pneumophila subsp. pneumophila strain FFI102]
MRMDKLTSKFQMALADAQSLALGRDNGFIEPEHLMKALLDQQGGSCRPLLSKAGVNIPLLRTLIDQALDKLPKVSGTGGD
IHISNALNRLLNLTDKLSQQRKDNFISSELFILAAINEDSNLAKILKQAGGDNKAIEKAIDELRGGETVNDPNAEEQRQA
LEKYTLDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKNKRLLAL
DMGALIAGAKYRGEFEERLKGVLNDLAKQEGQIILFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVDEPSVEDTIAILRGLKERYEVHHGVEITDPALVAAATLSHRYISDRQLPDKAIDLIDEAASL
IRMEIDSKPESMDKLERRLIQLKIEREALKKENDEASKKRLVDLQKSIDELEQNYSDLEEIWKAEKATMQGSTQIKEALE
QAKLEMETARRAGDLSRMSELQYGRIPELEKRLSQVSSVDAMETKLVRNKVTEDEIAEVVSKWTGIPVSKMMEGEKEKLL
KMEEALHSRLIGQNEAVDAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALASFLFDTEEAMVRIDMSEFMEK
HSVARLIGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHTDVFNILLQVMDDGRLTDGQGRTVDFRNTVIVMTSNL
GSQLIQEMSSKFNYDEIKAAVMDLVSQHFRPEFINRIDESVVFHSLTKEQIAKIAAIQINYLHHRLKQQNITLEVTSEAL
SHLAEAGFDPVYGARPLKRTIQQKLENPLAQSLLTGKFKSGDTIIVSYKDGVMEFSKQ

Nucleotide

• Length: 2577 bp

>NTDB_id=164612 BE841_RS04280 WP_011215726.1 993810..996386(-) (clpC) [Legionella pneumophila subsp. pneumophila strain FFI102]
ATGCGAATGGACAAACTAACATCAAAGTTTCAAATGGCACTTGCAGATGCCCAATCCCTGGCTTTAGGTAGAGACAATGG
ATTTATAGAACCAGAACATTTAATGAAGGCCTTGCTTGATCAGCAAGGCGGAAGTTGCAGACCTCTTCTCAGTAAAGCGG
GTGTTAATATACCACTATTAAGAACTTTAATTGACCAAGCTCTGGATAAACTACCTAAAGTATCAGGCACCGGGGGAGAT
ATTCACATATCTAATGCATTGAATAGACTACTTAACCTGACTGACAAATTATCGCAACAAAGAAAAGACAACTTTATTTC
AAGCGAGCTTTTTATATTAGCAGCGATAAATGAGGATAGTAACCTGGCAAAAATACTTAAACAAGCTGGGGGTGACAACA
AGGCGATTGAAAAAGCAATTGATGAGTTAAGAGGTGGAGAAACAGTTAATGATCCAAATGCAGAGGAACAGCGACAAGCC
CTTGAAAAATATACACTGGATCTGACTGAACGTGCCGAGCAAGGAAAATTGGATCCAGTTATTGGACGAGATGATGAAAT
CAGACGCACCATCCAGGTATTGCAAAGAAGAACTAAAAATAACCCTGTATTAATAGGTGAACCTGGTGTTGGTAAAACAG
CCATAGTAGAAGGTTTGGCACAACGAATTATTAATGGTGAAGTACCTGAAGGATTAAAGAATAAACGCTTACTGGCACTG
GACATGGGTGCCTTGATCGCAGGTGCAAAATATCGTGGAGAGTTTGAAGAACGCTTAAAAGGAGTGCTTAATGATTTGGC
AAAACAAGAGGGTCAAATCATATTATTTATTGATGAATTACACACTATGGTTGGCGCTGGTAAGGCCGAAGGGGCTATGG
ATGCAGGGAATATGCTCAAGCCAGCATTGGCTAGAGGTGAATTGCATTGCATTGGAGCTACGACATTAGATGAATACCGA
CAATACATTGAAAAGGATGCTGCCCTTGAGCGACGTTTTCAAAAAGTACTGGTCGATGAACCCAGTGTGGAAGACACTAT
CGCTATATTAAGGGGACTTAAGGAACGTTATGAAGTTCACCATGGAGTTGAAATTACAGATCCCGCTCTGGTTGCTGCAG
CAACGCTATCCCATCGTTACATCAGCGACCGTCAACTACCCGATAAAGCCATTGATTTAATTGACGAAGCCGCCAGTTTA
ATCCGGATGGAAATTGATTCAAAACCAGAAAGTATGGATAAACTGGAACGACGCTTGATTCAGCTAAAAATCGAGCGTGA
AGCATTGAAAAAGGAAAATGACGAAGCGTCTAAAAAAAGACTTGTTGATTTACAAAAAAGTATCGATGAATTAGAGCAAA
ATTATTCAGACTTAGAAGAAATTTGGAAAGCTGAAAAAGCGACCATGCAAGGGTCCACTCAAATCAAAGAAGCACTTGAG
CAAGCCAAACTGGAAATGGAAACTGCAAGGAGAGCAGGAGATTTAAGCCGTATGTCCGAATTACAATATGGACGTATACC
CGAGCTGGAAAAAAGATTAAGCCAGGTCTCTTCCGTCGATGCTATGGAAACAAAGTTAGTACGCAATAAAGTCACCGAAG
ATGAGATCGCAGAAGTTGTTTCAAAATGGACAGGAATCCCGGTATCTAAAATGATGGAAGGTGAAAAGGAAAAACTGCTG
AAAATGGAAGAAGCTTTGCATAGTAGACTCATTGGCCAGAATGAAGCGGTGGATGCTGTTTCTAATGCCATAAGACGGTC
ACGCGCAGGCCTGTCTGATCCTAATCGTCCAATTGGTTCATTTCTTTTTCTGGGGCCAACTGGTGTGGGAAAAACTGAAC
TATGCAAAGCACTTGCTTCTTTTCTTTTTGATACGGAAGAGGCGATGGTGCGCATTGATATGTCTGAATTTATGGAAAAA
CACTCTGTTGCGCGCTTAATCGGAGCGCCTCCTGGCTATGTAGGATATGAGGAGGGTGGCTATTTAACTGAAGCAGTCAG
ACGCAGGCCCTATTCTGTTATCTTACTTGATGAAGTAGAAAAAGCTCATACAGATGTATTTAATATTCTGCTTCAAGTGA
TGGATGATGGCCGTCTAACAGATGGTCAGGGGCGTACTGTTGACTTTAGGAATACCGTTATTGTTATGACCTCTAATCTG
GGATCTCAACTCATTCAGGAAATGAGCAGCAAATTTAATTACGATGAGATTAAGGCTGCGGTAATGGATTTAGTCAGCCA
ACATTTCAGACCTGAATTTATCAACAGAATTGATGAATCGGTGGTATTCCATTCCCTGACAAAAGAACAAATTGCAAAAA
TTGCAGCAATCCAGATTAACTATTTACATCACCGGCTGAAACAACAAAACATCACTCTTGAAGTCACAAGTGAGGCTTTA
TCTCATTTGGCTGAAGCAGGATTTGATCCGGTCTATGGTGCCCGCCCCCTAAAACGTACTATTCAGCAAAAATTAGAGAA
TCCACTAGCTCAATCATTATTGACTGGAAAATTTAAATCCGGGGATACCATTATTGTATCTTATAAAGATGGAGTAATGG
AATTTTCCAAGCAATGA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-846)

• AAA lid domain (AAA_lid_9) (342-444)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-759)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-335)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.066	100	0.477
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.061	100	0.415
clpC	Lactococcus lactis subsp. cremoris KW2	46.454	80.536	0.374
clpE	Streptococcus pneumoniae D39	45.428	80.303	0.365
clpE	Streptococcus pneumoniae R6	45.428	80.303	0.365
clpE	Streptococcus pneumoniae TIGR4	45.428	80.303	0.365
clpE	Streptococcus pneumoniae Rx1	45.428	80.303	0.365
clpE	Streptococcus mutans UA159	46.097	79.138	0.365