Detailed information NTG0164293

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: A7U44_RS10735
• Genome accession: NZ_CP016856
• Coordinates: 2112584..2113297 (-)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus strain 2148.N
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2107584..2118297

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7U44_RS10705 (A7U44_04520)	sph	2108362..2109186 (-)	825	Protein_2014	sphingomyelin phosphodiesterase	-
A7U44_RS10710 (A7U44_0740)	-	2109243..2110280 (-)	1038	WP_000857191.1	tyrosine-type recombinase/integrase	-
A7U44_RS10715 (A7U44_0741)	-	2110339..2110803 (-)	465	WP_000825947.1	hypothetical protein	-
A7U44_RS10720 (A7U44_0742)	-	2110903..2111085 (-)	183	WP_000705248.1	hypothetical protein	-
A7U44_RS10725 (A7U44_0743)	-	2111289..2111630 (-)	342	WP_000591749.1	hypothetical protein	-
A7U44_RS10730 (A7U44_0744)	-	2111636..2112568 (-)	933	WP_000759682.1	exonuclease domain-containing protein	-
A7U44_RS10735 (A7U44_0745)	irvR	2112584..2113297 (-)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
A7U44_RS10740 (A7U44_04525)	-	2113260..2113433 (+)	174	WP_001801500.1	hypothetical protein	-
A7U44_RS10745 (A7U44_0746)	-	2113430..2113693 (+)	264	WP_000854073.1	helix-turn-helix transcriptional regulator	-
A7U44_RS10750 (A7U44_0747)	-	2113709..2113906 (+)	198	WP_001148862.1	hypothetical protein	-
A7U44_RS10755 (A7U44_0748)	-	2113893..2114273 (-)	381	WP_000762519.1	DUF2513 domain-containing protein	-
A7U44_RS10760 (A7U44_0749)	-	2114328..2114651 (+)	324	WP_001120201.1	DUF771 domain-containing protein	-
A7U44_RS10765 (A7U44_04530)	-	2114648..2114809 (+)	162	WP_000048129.1	DUF1270 family protein	-
A7U44_RS10770 (A7U44_0750)	-	2114904..2115206 (+)	303	WP_000165371.1	DUF2482 family protein	-
A7U44_RS10775 (A7U44_0751)	-	2115211..2115471 (+)	261	WP_000291510.1	DUF1108 family protein	-
A7U44_RS10780 (A7U44_04535)	-	2115480..2115743 (+)	264	WP_001205732.1	hypothetical protein	-
A7U44_RS10785 (A7U44_0753)	-	2115752..2117695 (+)	1944	WP_000700555.1	AAA family ATPase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=164293 A7U44_RS10735 WP_001031454.1 2112584..2113297(-) (irvR) [Staphylococcus aureus strain 2148.N]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=164293 A7U44_RS10735 WP_001031454.1 2112584..2113297(-) (irvR) [Staphylococcus aureus strain 2148.N]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCTTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401