Detailed information NTG0164051

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: AU077_RS05935
• Genome accession: NZ_CP013688
• Coordinates: 1194390..1195256 (-)
• Length: 288 a.a.
• NCBI ID: WP_039670637.1
• Uniprot ID: A0A380K5F1
• Organism: Streptococcus gallolyticus strain ICDDRB-NRC-S1
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1189390..1200256

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AU077_RS05920 (AU077_05920)	-	1191861..1192385 (-)	525	WP_058621746.1	GNAT family N-acetyltransferase	-
AU077_RS05925 (AU077_05925)	pheS	1192421..1193464 (-)	1044	WP_013642932.1	phenylalanine--tRNA ligase subunit alpha	-
AU077_RS05930 (AU077_05930)	-	1193914..1194159 (-)	246	Protein_1211	GNAT family N-acetyltransferase	-
AU077_RS11970	-	1194187..1194321 (-)	135	WP_257235419.1	hypothetical protein	-
AU077_RS05935 (AU077_05935)	endA	1194390..1195256 (-)	867	WP_039670637.1	DNA/RNA non-specific endonuclease	Machinery gene
AU077_RS05940 (AU077_05940)	-	1195372..1195560 (-)	189	WP_009853912.1	DNA-directed RNA polymerase subunit beta	-
AU077_RS05945 (AU077_05945)	murA	1195563..1196837 (-)	1275	WP_058621747.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
AU077_RS05950 (AU077_05950)	-	1196900..1197136 (-)	237	WP_014294304.1	DUF1146 family protein	-
AU077_RS05955 (AU077_05955)	-	1197201..1197617 (-)	417	WP_058621748.1	F0F1 ATP synthase subunit epsilon	-
AU077_RS05960 (AU077_05960)	atpD	1197630..1199036 (-)	1407	WP_058621749.1	F0F1 ATP synthase subunit beta	-
AU077_RS05965 (AU077_05965)	-	1199103..1199981 (-)	879	WP_058621750.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 288 a.a.
• Molecular weight: 30873.94 Da
• Isoelectric Point: 5.6882

>NTDB_id=164051 AU077_RS05935 WP_039670637.1 1194390..1195256(-) (endA) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
MAKKSKLSKQTKSLMSLVILLVGIGAGWVTISDSNDPLNQVVSLITGDSSSEITSNQSSSDSATPTQSLAETVLTDSVKE
QLGENIEWNGAGAYIINDNQTSLNAKVSSQPYANNKTKTVQGQTVPTVANALLSKSTRQYKSREETGNGSTSWTPAGWHQ
VQDLSGTYSHAVDRGHLLGYALVGGLKGFDASTSNPDNVATQTAWANEANSESSTGQNYYESLVRKALDQKKRVRYRVTL
IYDGDNLLASGTHLEAKSSDGSLEFNVFVPNVQSGLTFDYYSGQVSVN

Nucleotide

• Length: 867 bp

>NTDB_id=164051 AU077_RS05935 WP_039670637.1 1194390..1195256(-) (endA) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
ATGGCAAAGAAATCAAAATTGTCTAAACAGACAAAATCCCTGATGTCTTTGGTGATTTTGTTAGTTGGTATTGGTGCTGG
TTGGGTGACGATATCAGATTCGAATGATCCGCTAAATCAAGTTGTTTCGTTAATTACTGGTGACTCCTCTTCTGAAATAA
CGTCAAATCAATCGAGTTCAGATTCGGCAACGCCAACACAATCTTTAGCAGAGACGGTATTAACAGATAGTGTCAAAGAG
CAGTTAGGAGAAAATATAGAATGGAATGGTGCGGGAGCCTATATTATCAATGATAATCAAACATCCCTAAATGCAAAAGT
TTCAAGTCAACCTTACGCCAACAACAAAACGAAAACGGTGCAAGGTCAGACTGTTCCAACGGTTGCTAATGCTTTGCTAA
GTAAGTCAACTCGTCAATACAAAAGTCGTGAGGAAACAGGAAATGGGTCGACCTCTTGGACGCCTGCGGGTTGGCATCAA
GTTCAAGACCTTTCAGGGACTTATAGCCATGCGGTAGACCGTGGGCATTTGCTTGGCTATGCTTTGGTTGGTGGTCTAAA
AGGCTTTGATGCGTCAACAAGCAACCCTGACAATGTGGCAACACAGACGGCTTGGGCGAACGAGGCAAATTCGGAAAGTT
CAACTGGTCAAAATTACTATGAATCCCTTGTCCGCAAAGCTCTTGACCAGAAAAAACGAGTTCGTTATCGTGTCACCTTG
ATTTATGACGGTGATAATCTCTTAGCAAGCGGAACGCATTTGGAAGCCAAATCATCTGACGGTAGTCTAGAATTTAACGT
CTTTGTTCCAAATGTGCAAAGCGGACTGACATTTGATTATTATTCAGGTCAAGTTAGTGTGAATTGA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (95-247)

3D structure

• AlphaFold DB: A0A380K5F1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	66.129	86.111	0.569
endA	Streptococcus pneumoniae D39	66.129	86.111	0.569
endA	Streptococcus pneumoniae R6	66.129	86.111	0.569
endA	Streptococcus pneumoniae TIGR4	66.129	86.111	0.569