Detailed information NTG0163801

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: AUQ45_RS06280
• Genome accession: NZ_CP013672
• Coordinates: 1232558..1233595 (-)
• Length: 345 a.a.
• NCBI ID: WP_011284961.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain AP53
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1227558..1238595

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AUQ45_RS06255 (AUQ45_1252)	-	1227562..1228089 (-)	528	WP_014635585.1	Dps family protein	-
AUQ45_RS06260 (AUQ45_1253)	-	1228317..1228943 (+)	627	WP_002989076.1	A24 family peptidase	-
AUQ45_RS06265 (AUQ45_1254)	rlmN	1229025..1230104 (-)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
AUQ45_RS06270 (AUQ45_1255)	-	1230108..1230728 (-)	621	WP_002992791.1	YutD family protein	-
AUQ45_RS06275 (AUQ45_1257)	-	1231176..1232153 (-)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
AUQ45_RS06280 (AUQ45_1258)	sepM	1232558..1233595 (-)	1038	WP_011284961.1	SepM family pheromone-processing serine protease	Regulator
AUQ45_RS06285 (AUQ45_1259)	coaD	1233582..1234073 (-)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
AUQ45_RS06290 (AUQ45_1260)	rsmD	1234063..1234602 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
AUQ45_RS06295 (AUQ45_1261)	asnA	1234725..1235717 (-)	993	WP_002983817.1	aspartate--ammonia ligase	-
AUQ45_RS06300 (AUQ45_1262)	arcC	1236030..1236980 (-)	951	WP_010922501.1	carbamate kinase	-
AUQ45_RS06305 (AUQ45_1263)	-	1237000..1238331 (-)	1332	WP_011285641.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37571.27 Da
• Isoelectric Point: 9.6692

>NTDB_id=163801 AUQ45_RS06280 WP_011284961.1 1232558..1233595(-) (sepM) [Streptococcus pyogenes strain AP53]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDTDFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=163801 AUQ45_RS06280 WP_011284961.1 1232558..1233595(-) (sepM) [Streptococcus pyogenes strain AP53]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATACTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAG

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.986	100	0.69