Detailed information NTG0163793

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: AUQ45_RS04575
• Genome accession: NZ_CP013672
• Coordinates: 897007..897843 (+)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain AP53
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 892007..902843

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AUQ45_RS04545 (AUQ45_0892)	-	892489..892929 (+)	441	WP_009880949.1	hypothetical protein	-
AUQ45_RS04550 (AUQ45_0893)	-	892979..893890 (-)	912	WP_002984631.1	diacylglycerol kinase family protein	-
AUQ45_RS04555 (AUQ45_0894)	-	894007..894657 (-)	651	WP_002984629.1	hemolysin III family protein	-
AUQ45_RS04560 (AUQ45_0895)	-	894654..895094 (-)	441	WP_002984627.1	DUF1836 domain-containing protein	-
AUQ45_RS04565 (AUQ45_0896)	ylqF	895313..896161 (+)	849	WP_014635467.1	ribosome biogenesis GTPase YlqF	-
AUQ45_RS04570 (AUQ45_0897)	-	896151..896942 (+)	792	WP_002995007.1	ribonuclease HII	-
AUQ45_RS04575 (AUQ45_0898)	dprA	897007..897843 (+)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
AUQ45_RS04580 (AUQ45_0899)	topA	897950..900079 (+)	2130	WP_002984618.1	type I DNA topoisomerase	-
AUQ45_RS04585 (AUQ45_0900)	-	900198..901331 (+)	1134	WP_000564846.1	ISAs1-like element IS1548 family transposase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=163793 AUQ45_RS04575 WP_002995009.1 897007..897843(+) (dprA) [Streptococcus pyogenes strain AP53]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=163793 AUQ45_RS04575 WP_002995009.1 897007..897843(+) (dprA) [Streptococcus pyogenes strain AP53]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367