Detailed information NTG0163354

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AUC50_RS14055
• Genome accession: NZ_CP013621
• Coordinates: 2776899..2777786 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain RIVM3897
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2771899..2782786

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AUC50_RS14020 (AUC50_14010)	-	2771908..2772000 (+)	93	WP_031774855.1	hypothetical protein	-
AUC50_RS14025 (AUC50_14015)	-	2772108..2772605 (-)	498	WP_001065267.1	glutathione peroxidase	-
AUC50_RS14030 (AUC50_14020)	-	2772615..2772875 (-)	261	WP_014937088.1	hypothetical protein	-
AUC50_RS14035 (AUC50_14025)	-	2773257..2773370 (-)	114	WP_014937089.1	hypothetical protein	-
AUC50_RS14045 (AUC50_14035)	-	2774039..2776039 (-)	2001	WP_000776741.1	ABC transporter permease	-
AUC50_RS14050 (AUC50_14040)	-	2776036..2776791 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
AUC50_RS14055 (AUC50_14045)	braS	2776899..2777786 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AUC50_RS14060 (AUC50_14050)	braR	2777797..2778462 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AUC50_RS14065 (AUC50_14055)	-	2778488..2778688 (-)	201	WP_000604731.1	hypothetical protein	-
AUC50_RS14075 (AUC50_14065)	-	2778886..2780310 (+)	1425	WP_060585392.1	alkaline phosphatase	-
AUC50_RS15955	-	2780370..2780471 (-)	102	WP_000731972.1	SE2200 family small protein	-
AUC50_RS14080 (AUC50_14070)	-	2780593..2781048 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AUC50_RS14085 (AUC50_14075)	-	2781292..2782053 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=163354 AUC50_RS14055 WP_000143420.1 2776899..2777786(-) (braS) [Staphylococcus aureus strain RIVM3897]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=163354 AUC50_RS14055 WP_000143420.1 2776899..2777786(-) (braS) [Staphylococcus aureus strain RIVM3897]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993