Detailed information NTG0163268

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AUC48_RS13440
• Genome accession: NZ_CP013616
• Coordinates: 2672349..2673236 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain RIVM1295
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2667349..2678236

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AUC48_RS13405 (AUC48_13395)	-	2667358..2667450 (+)	93	WP_031774855.1	hypothetical protein	-
AUC48_RS13410 (AUC48_13400)	-	2667558..2668055 (-)	498	WP_001065267.1	glutathione peroxidase	-
AUC48_RS13415 (AUC48_13405)	-	2668065..2668325 (-)	261	WP_014937088.1	hypothetical protein	-
AUC48_RS13420 (AUC48_13410)	-	2668707..2668820 (-)	114	WP_014937089.1	hypothetical protein	-
AUC48_RS13430 (AUC48_13420)	-	2669489..2671489 (-)	2001	WP_000776741.1	ABC transporter permease	-
AUC48_RS13435 (AUC48_13425)	-	2671486..2672241 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
AUC48_RS13440 (AUC48_13430)	braS	2672349..2673236 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AUC48_RS13445 (AUC48_13435)	braR	2673247..2673912 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AUC48_RS13450 (AUC48_13440)	-	2673938..2674138 (-)	201	WP_000604731.1	hypothetical protein	-
AUC48_RS13460 (AUC48_13450)	-	2674336..2675760 (+)	1425	WP_031796859.1	alkaline phosphatase	-
AUC48_RS15095	-	2675820..2675921 (-)	102	WP_000731972.1	SE2200 family small protein	-
AUC48_RS13465 (AUC48_13455)	-	2676043..2676498 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AUC48_RS13470 (AUC48_13460)	-	2676742..2677503 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=163268 AUC48_RS13440 WP_000143420.1 2672349..2673236(-) (braS) [Staphylococcus aureus strain RIVM1295]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=163268 AUC48_RS13440 WP_000143420.1 2672349..2673236(-) (braS) [Staphylococcus aureus strain RIVM1295]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993