Detailed information NTG0161746

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: A6L48_RS08310
• Genome accession: NZ_CP016654
• Coordinates: 1564469..1567048 (+)
• Length: 859 a.a.
• NCBI ID: WP_002235021.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain M22811
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1559469..1572048

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6L48_RS08290 (A6L48_08290)	ppx	1560227..1561735 (+)	1509	WP_002258642.1	exopolyphosphatase	-
A6L48_RS08295 (A6L48_08295)	-	1561944..1562267 (-)	324	WP_002225099.1	Ag473 family lipoprotein	-
A6L48_RS08300 (A6L48_08300)	-	1562586..1563131 (-)	546	WP_002235019.1	hypothetical protein	-
A6L48_RS08305 (A6L48_08305)	trpS	1563199..1564209 (-)	1011	WP_002235020.1	tryptophan--tRNA ligase	-
A6L48_RS08310 (A6L48_08310)	clpC	1564469..1567048 (+)	2580	WP_002235021.1	ATP-dependent chaperone ClpB	Regulator
A6L48_RS08315 (A6L48_08315)	-	1567135..1568349 (-)	1215	WP_002220612.1	pyridoxal phosphate-dependent aminotransferase	-
A6L48_RS08320 (A6L48_08320)	-	1568438..1568647 (-)	210	WP_002212949.1	tautomerase family protein	-
A6L48_RS08325 (A6L48_08325)	-	1568992..1569798 (+)	807	WP_002212946.1	DUF4198 domain-containing protein	-
A6L48_RS08330 (A6L48_08330)	-	1569856..1571121 (-)	1266	WP_002257138.1	Glu/Leu/Phe/Val family dehydrogenase	-

Sequence

Protein

• Length: 859 a.a.
• Molecular weight: 95158.61 Da
• Isoelectric Point: 5.3090

>NTDB_id=161746 A6L48_RS08310 WP_002235021.1 1564469..1567048(+) (clpC) [Neisseria meningitidis strain M22811]
MRYDKLTAKFQQALAEAQSLALAADGSYLEAGFVLKALLDDQNSGAAALLAHSGVNVPQVKQRLQQHLSSLPKVSGQGGD
IMPSRELQAVLNLMDKAATKRGDVYIASELFLLALVQQNDATGKILKEAGATEQNINAAIDAVRGGQNVNDANAEDQRDA
LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASR
VKMEKETKPEAMDKIDRRLIQLRMEKAHVEKEKDDASKKRLELIDEEINGLQKEYADLDEIWKAEKAISDGAANIKKQID
EVKIKIEQAKRQGDLALASKLMYEDLEHLEKQRAAAERADTDSTKPANKLLRNNVGAEEIAEVVSRMTGIPVSKMMEGER
DKLLKMEEVLHRRVVGQDEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSE
YMEKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVM
TSNIGSQHIQQMGIQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKIQLKGLEKRLEKQNLRLTVSD
AALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIRVEADGDRLKFA

Nucleotide

• Length: 2580 bp

>NTDB_id=161746 A6L48_RS08310 WP_002235021.1 1564469..1567048(+) (clpC) [Neisseria meningitidis strain M22811]
ATGCGATACGACAAATTAACCGCCAAATTCCAACAAGCCCTTGCAGAAGCTCAGAGTTTGGCGTTGGCTGCGGACGGCAG
CTATCTGGAAGCAGGCTTTGTGTTAAAAGCCCTGCTTGACGACCAAAACAGCGGTGCCGCCGCGTTGCTGGCGCATTCGG
GCGTGAACGTGCCGCAGGTGAAACAGCGTTTGCAGCAGCATTTGAGCAGCCTGCCGAAAGTGTCCGGCCAGGGCGGCGAT
ATTATGCCTAGCCGTGAGCTGCAAGCTGTATTGAACTTGATGGACAAAGCCGCAACCAAGCGCGGCGATGTCTATATCGC
CAGCGAACTTTTCCTGCTTGCCTTGGTGCAGCAGAACGATGCAACCGGCAAAATTTTGAAAGAAGCCGGTGCGACCGAAC
AAAACATTAATGCCGCGATTGATGCGGTACGAGGAGGACAAAACGTGAATGATGCGAATGCCGAAGACCAACGCGATGCT
TTGAAAAAATACACACTTGATCTGACCCAGCGCGCCCGCGACGGCAAACTTGACCCCGTTATCGGCCGTGATGATGAAAT
CCGCCGCGCGATTCAGGTATTGCAACGCCGTACCAAAAACAACCCCGTGCTGATTGGTGAGCCGGGTGTGGGTAAAACCG
CTATTGTTGAAGGCTTGGCGCAACGTATCGTCAACGGCGAAGTGCCTGAATCCCTGCGCAACAAACGCCTGCTGGTTCTG
GACTTGGCGGCTTTGATTGCCGGCGCGAAATATCGCGGCGAATTTGAAGAACGCTTGAAAGGCGTGTTGAACGACTTGGC
GAAAGACGATGGCAACACTCTGATTTTCATCGACGAAATTCATACCTTGGTTGGCGCAGGTAAAACCGACGGCGCGATGG
ACGCGGGCAATATGTTGAAACCGGCTTTGGCACGCGGCGAACTGCACTGTATCGGTGCGACCACCTTGGACGAATACCGC
CAATACATCGAAAAAGACGCGGCACTCGAACGCCGTTTCCAAAAAGTATTGGTTGGCGAGCCCAGCGTGGAAGACACCAT
CGCCATCTTGCGCGGTTTGCAGGAGCGTTATGAAATCCACCACGGTATCGATATTACCGACCCTGCTATCGTTGCCGCAG
CGGAGTTGAGCGACCGCTACATCACCGACCGCTTCCTGCCCGATAAAGCGATTGATTTGATTGACGAAGCCGCCAGCCGT
GTCAAGATGGAAAAAGAAACCAAGCCGGAAGCAATGGACAAAATCGACCGCCGTCTAATTCAGCTTCGGATGGAAAAGGC
GCACGTTGAAAAAGAAAAAGACGATGCCAGCAAAAAACGTTTGGAACTGATAGACGAGGAAATCAACGGTCTGCAAAAAG
AATACGCCGATTTAGACGAAATCTGGAAAGCCGAAAAAGCAATTTCAGACGGTGCTGCTAATATTAAGAAACAAATTGAC
GAAGTCAAAATTAAAATCGAACAGGCAAAACGGCAAGGCGATTTGGCACTGGCTTCAAAATTGATGTATGAAGATTTGGA
GCATTTGGAAAAACAGCGTGCAGCCGCCGAACGGGCAGATACGGACAGCACAAAACCGGCAAACAAACTCTTGCGTAATA
ATGTCGGCGCAGAGGAAATCGCAGAGGTGGTTTCCCGTATGACCGGCATTCCCGTATCCAAAATGATGGAAGGCGAACGC
GACAAACTGCTGAAAATGGAAGAAGTATTGCACCGCCGCGTGGTCGGACAGGACGAAGCCGTGCGTGCCGTGTCCGACGC
TATCCGCCGCAGCCGCTCCGGTCTTGCCGATCCGAACAAGCCTTACGGCAGCTTCCTGTTCTTGGGCCCGACCGGCGTGG
GTAAAACCGAGTTGTGTAAAGCCCTGGCAGGCTTTCTGTTCGACAGCGAAGATCATCTGATTCGCATCGATATGTCCGAA
TATATGGAAAAACACGCCGTTGCACGCCTGATCGGTGCGCCTCCGGGCTATGTCGGCTACGAAGAAGGCGGCTACCTGAC
CGAACAAGTGCGCCGCAAACCGTACAGCGTGATTCTGCTGGACGAAGTGGAAAAAGCCCATCCCGATGTGTTCAACATCC
TGCTGCAAGTATTGGATGACGGTCGTTTGACCGACGGGCAAGGCAGGACGGTAGATTTTAAAAATACCGTGATTGTGATG
ACTTCCAACATCGGCAGCCAGCACATCCAACAAATGGGCATTCAGGATTACGAAGCGGTAAAAGAAGTTGTGATGGAGGA
TGTGAAAGAACATTTCCGTCCTGAAATGATCAACCGCATCGACGAAGTGGTCGTGTTCCACGGTTTGGATCAGGCAAACA
TCCGCAGCATTGCGAAAATCCAGCTCAAAGGTTTGGAAAAACGTTTGGAAAAACAAAACCTGCGCCTGACTGTTTCCGAT
GCCGCACTGGACATCATCGCCAAAGCCGGTTTCGACCCGATTTACGGCGCACGTCCGCTCAAACGCGCCATCCAGTCGGA
AATCGAAAACCCGCTGGCAAAAGCCCTGCTTGCCGGAAACTATGCGCCCGAAAGCGAAATCAGGGTAGAAGCCGACGGCG
ACAGACTGAAATTTGCCTGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (601-763)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (769-849)

• AAA lid domain (AAA_lid_9) (342-442)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	43.786	100	0.439
clpC	Streptococcus pneumoniae TIGR4	38.87	100	0.409
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	38.685	100	0.404
clpC	Lactococcus lactis subsp. cremoris KW2	47.118	80.792	0.381
clpE	Streptococcus pneumoniae TIGR4	47.206	79.162	0.374
clpC	Streptococcus pneumoniae Rx1	44.35	82.421	0.366
clpC	Streptococcus pneumoniae D39	44.35	82.421	0.366