Detailed information NTG0161003

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: APQ13_RS08380
• Genome accession: NZ_CP013237
• Coordinates: 1741900..1744341 (+)
• Length: 813 a.a.
• NCBI ID: WP_002266892.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain NG8 isolate Dental Plaque
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1736900..1749341

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
APQ13_RS08360 (APQ13_08340)	-	1737217..1739070 (+)	1854	WP_002270978.1	hypothetical protein	-
APQ13_RS08365 (APQ13_08345)	rpsB	1739260..1740045 (+)	786	WP_002262347.1	30S ribosomal protein S2	-
APQ13_RS08370 (APQ13_08350)	tsf	1740112..1741158 (+)	1047	WP_002266891.1	translation elongation factor Ts	-
APQ13_RS08375 (APQ13_08355)	ctsR	1741439..1741903 (+)	465	WP_002262345.1	transcriptional regulator CtsR	-
APQ13_RS08380 (APQ13_08360)	clpC	1741900..1744341 (+)	2442	WP_002266892.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
APQ13_RS08385 (APQ13_08365)	-	1744626..1747013 (+)	2388	WP_002268484.1	glycoside hydrolase family 68 protein	-
APQ13_RS08390 (APQ13_08370)	-	1747203..1747889 (-)	687	WP_002266894.1	helix-turn-helix domain-containing protein	-
APQ13_RS08395 (APQ13_08375)	rpsJ	1748209..1748517 (+)	309	WP_002262341.1	30S ribosomal protein S10	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90343.13 Da
• Isoelectric Point: 6.9065

>NTDB_id=161003 APQ13_RS08380 WP_002266892.1 1741900..1744341(+) (clpC) [Streptococcus mutans strain NG8 isolate Dental Plaque]
MTDYSLKMQEVFRLAQFEAARFESSYLESWHVLLAMVEIDSSVAGLSFAEFEADVRFEDYQAAAILAIGKKPKSSSNDIM
LLEQSHALKRTLAEAAAISQVTHAKEVGTEHVLFAMLLNPNLLATRILELVGFHAKDDGESIRLLDLRKVIERYAGFSKE
DIKAIFEMRKPKKVKNSSSFSDLMKPPSVTGELADFTRDLTELARQGRLEPVIGREQEISRMVQILSRKTKNNPVLVGDA
GVGKTALAYGLAQRIVDSAVPFELADMKVLELDMMSVVAGTRFRGDFEERMNQIIADIEADGHIVLFIDELHTIMGSGSG
IDSTLDAANILKPALARGSLRTIGATTQEEYQKHIEKDAALSRRFAKVTIEEPSEEEAYQILLGLKKSYETYHHVIISDA
AVMAAVKGAHRYLNGKNLPDSAIDLLDEASATVQGLVKKKAPAYLTDLDHALITNDYQLAKRLLKKEKKPLLKKRAEVKE
EDILATLSKLSGIPVKKLTQADSKKYLNLERELHKRVIGQDDAVSSISRAIRRNQSGIRVGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNILLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKSFSQDYKAMESRILEELKKVYRPEFINRIDEKVVFHN
LGQEDIRHVVKIMVAPLIAHLADQGITLKFQPSALKHLALAGYDAEMGARPLRRTLQTEVEDKLAELILSGKLASGQTLK
IGIQKEKLKFDIV

Nucleotide

• Length: 2442 bp

>NTDB_id=161003 APQ13_RS08380 WP_002266892.1 1741900..1744341(+) (clpC) [Streptococcus mutans strain NG8 isolate Dental Plaque]
ATGACCGATTACTCATTAAAAATGCAGGAAGTCTTTCGATTGGCGCAGTTTGAAGCAGCTCGTTTTGAAAGTTCCTATTT
AGAAAGCTGGCATGTCCTTCTTGCAATGGTAGAGATTGATTCCTCAGTGGCTGGTTTAAGTTTTGCGGAGTTTGAAGCAG
ATGTCCGTTTTGAGGATTATCAGGCTGCTGCTATTTTGGCGATTGGTAAAAAGCCTAAGTCCTCGAGTAATGATATTATG
CTTTTAGAGCAATCACATGCTTTAAAACGAACCCTAGCAGAGGCCGCTGCTATTAGTCAGGTGACACACGCTAAAGAAGT
CGGCACAGAACATGTTCTCTTTGCTATGTTACTGAATCCTAATCTTTTGGCGACTCGCATTTTAGAATTAGTTGGTTTTC
ACGCCAAAGATGATGGAGAGTCCATCCGTCTTTTGGATCTGCGAAAAGTGATTGAACGTTATGCTGGCTTTTCCAAAGAG
GACATTAAGGCCATCTTTGAAATGCGTAAACCTAAAAAGGTCAAAAATAGCAGCAGCTTTTCTGATTTAATGAAGCCACC
TAGCGTTACAGGTGAACTAGCTGATTTTACACGGGATTTGACGGAGTTGGCAAGACAAGGTCGTTTAGAACCTGTTATTG
GCCGTGAACAAGAAATTTCACGGATGGTTCAAATTTTAAGCCGTAAGACAAAAAATAACCCTGTTTTAGTTGGCGATGCT
GGTGTTGGGAAGACGGCCTTGGCTTACGGCCTTGCTCAACGTATTGTGGATAGTGCCGTTCCTTTTGAATTGGCAGATAT
GAAAGTACTAGAGCTCGATATGATGAGTGTTGTTGCAGGGACTCGTTTTCGTGGCGATTTTGAGGAACGAATGAATCAAA
TTATTGCAGACATTGAAGCAGATGGTCACATTGTCCTCTTCATTGATGAGCTGCATACCATTATGGGTTCAGGAAGTGGT
ATTGATAGTACGCTGGATGCTGCTAATATTCTTAAACCAGCTTTAGCGCGCGGCAGTCTTAGAACGATTGGAGCGACTAC
TCAAGAGGAGTATCAAAAGCATATTGAAAAAGATGCTGCTCTTTCTCGCCGTTTTGCTAAGGTAACTATTGAAGAACCAA
GTGAAGAAGAAGCTTATCAGATCTTGCTTGGTTTAAAGAAGAGTTATGAAACTTATCATCATGTTATTATTTCTGATGCA
GCCGTAATGGCGGCAGTCAAAGGAGCACATCGTTATTTAAATGGTAAAAATTTACCTGATTCGGCTATCGATCTTTTAGA
TGAAGCTAGTGCAACTGTTCAAGGCTTAGTGAAAAAAAAGGCACCAGCTTATTTGACAGATTTAGATCATGCTCTTATCA
CTAACGATTACCAATTAGCTAAGCGTTTGCTGAAAAAGGAGAAGAAGCCTCTACTTAAAAAACGAGCTGAAGTCAAGGAA
GAAGATATCCTAGCTACTCTCAGCAAACTTTCAGGCATCCCTGTCAAAAAATTAACACAGGCTGACAGTAAAAAGTACCT
TAATCTCGAAAGGGAATTACATAAGCGTGTAATTGGTCAAGACGATGCGGTGTCCAGTATCAGCCGTGCTATTCGCCGCA
ATCAATCCGGAATTCGGGTTGGCAAACGTCCCATTGGCTCTTTCATGTTTTTGGGGCCGACAGGTGTTGGTAAAACAGAG
CTTGCTAAGGCTTTGGCAGAAGTGCTTTTTGATGATGAGTCAGCTCTTATTCGTTTTGACATGAGCGAATATATGGAAAA
ATTTGCAGCTTCTCGCCTTAATGGAGCTCCTCCGGGCTATGTGGGGTATGAAGAAGGCGGTGAGTTGACGGAAAAGGTTC
GTAACAAACCTTACTCTGTTCTTCTTTTTGATGAGGTGGAAAAAGCTCATCCAGATATTTTCAATATCTTACTTCAAGTA
CTTGATGATGGTGTTTTGACAGATAGCCGTGGTCGCAAAGTTGATTTTTCAAATACGATTATTATCATGACCTCTAATTT
GGGTGCGACTGCGCTTCGTGATGATAAAACCGTTGGTTTTGGAGCTAAAAGCTTTTCTCAGGATTATAAGGCCATGGAAA
GTCGTATTTTAGAGGAATTAAAAAAGGTTTACCGACCTGAATTTATTAATCGTATTGATGAAAAAGTTGTCTTTCATAAC
CTTGGTCAAGAAGACATACGCCATGTTGTTAAAATTATGGTTGCTCCATTGATTGCCCATTTGGCTGATCAGGGGATTAC
ACTTAAGTTTCAGCCTTCAGCTTTGAAACATTTAGCTCTGGCAGGTTATGATGCTGAAATGGGGGCACGTCCTTTGCGTC
GGACACTTCAGACAGAAGTGGAAGATAAGTTAGCAGAGCTTATTCTTTCGGGAAAACTAGCTAGTGGACAGACTCTGAAA
ATAGGTATTCAAAAAGAAAAATTAAAATTTGATATTGTATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (374-461)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (105-133)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-55)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-366)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	99.754	100	0.998
clpC	Streptococcus thermophilus LMD-9	72.426	100	0.727
clpC	Streptococcus thermophilus LMG 18311	72.304	100	0.726
clpC	Streptococcus pneumoniae TIGR4	67.076	100	0.672
clpC	Streptococcus pneumoniae Rx1	67.076	100	0.672
clpC	Streptococcus pneumoniae D39	67.076	100	0.672
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.98	100	0.502
clpC	Bacillus subtilis subsp. subtilis str. 168	43.584	100	0.443
clpE	Streptococcus pneumoniae TIGR4	47.2	76.876	0.363
clpE	Streptococcus pneumoniae Rx1	47.2	76.876	0.363
clpE	Streptococcus pneumoniae D39	47.2	76.876	0.363
clpE	Streptococcus pneumoniae R6	47.2	76.876	0.363
clpE	Streptococcus mutans UA159	47.04	76.876	0.362