Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB/nlmE   Type   Regulator
Locus tag   APQ13_RS06490 Genome accession   NZ_CP013237
Coordinates   1353277..1354179 (-) Length   300 a.a.
NCBI ID   WP_002263524.1    Uniprot ID   A0AAX1K0S8
Organism   Streptococcus mutans strain NG8 isolate Dental Plaque     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1348277..1359179
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APQ13_RS06470 (APQ13_06455) - 1348362..1348814 (-) 453 WP_002282263.1 PTS sugar transporter subunit IIA -
  APQ13_RS06475 (APQ13_06460) - 1348831..1349253 (-) 423 WP_002266695.1 PTS sugar transporter subunit IIA -
  APQ13_RS06480 (APQ13_06465) - 1349243..1350718 (-) 1476 WP_002273282.1 BglG family transcription antiterminator -
  APQ13_RS06485 (APQ13_06470) - 1351256..1352920 (-) 1665 WP_002289832.1 BglG family transcription antiterminator -
  APQ13_RS06490 (APQ13_06475) comB/nlmE 1353277..1354179 (-) 903 WP_002263524.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  APQ13_RS06495 (APQ13_06480) comA/nlmT 1354193..1356475 (-) 2283 WP_002274031.1 peptide cleavage/export ABC transporter Regulator
  APQ13_RS09930 - 1356904..1357080 (-) 177 WP_019319593.1 hypothetical protein -
  APQ13_RS06500 (APQ13_06485) - 1357129..1357536 (-) 408 WP_002263726.1 hypothetical protein -
  APQ13_RS06505 (APQ13_06490) - 1357561..1357779 (-) 219 WP_002278706.1 Blp family class II bacteriocin -
  APQ13_RS06510 (APQ13_06495) - 1358859..1359137 (-) 279 WP_002264456.1 hypothetical protein -

Sequence

Protein


Download         Length: 300 a.a.        Molecular weight: 34116.49 Da        Isoelectric Point: 10.4213

>NTDB_id=160988 APQ13_RS06490 WP_002263524.1 1353277..1354179(-) (comB/nlmE) [Streptococcus mutans strain NG8 isolate Dental Plaque]
MDPKFLQSAEFYRRRYHNFATLLIVPLVCLIIFLVIFLCFAKKEITVISTGEVAPTKVVDVIQSYSDSSIIKNNLDNNAA
VEKGDVLIEYSENASPNRQTEQKNIIKERQKREEKEKKKHQKSKKKKKSKSKKASKDKKKKSKDKESSSDDENETKKVSI
FASEDGIIHTNPKYDGANIIPKQTEIAQIYPDIQKTRKVLITYYASSDDVVSMKKGQTARLSLEKKGNDKVVIEGKINNV
ASSATTTKKGNLFKVTAKVKVSKKNSKLIKYGMTGKTVTVIDKKTYFDYFKDKLLHKMDN

Nucleotide


Download         Length: 903 bp        

>NTDB_id=160988 APQ13_RS06490 WP_002263524.1 1353277..1354179(-) (comB/nlmE) [Streptococcus mutans strain NG8 isolate Dental Plaque]
ATGGATCCTAAATTTTTACAAAGTGCAGAATTTTATAGGAGACGCTATCATAATTTTGCGACACTATTAATTGTTCCTTT
GGTCTGCTTGATTATCTTCTTGGTCATATTCCTTTGTTTTGCTAAAAAAGAAATTACAGTGATTTCTACTGGTGAAGTTG
CACCAACAAAGGTTGTAGATGTTATCCAATCTTACAGTGACAGTTCAATCATTAAAAATAATTTAGATAATAATGCAGCT
GTTGAGAAGGGAGACGTTTTAATTGAATATTCAGAAAATGCCAGTCCAAACCGTCAGACTGAACAAAAGAATATTATAAA
AGAAAGACAAAAACGAGAAGAGAAGGAAAAGAAAAAACACCAAAAGAGCAAGAAAAAGAAGAAGTCTAAGAGCAAGAAAG
CTTCCAAAGATAAGAAAAAGAAATCGAAAGACAAGGAAAGCAGCTCTGACGATGAAAATGAGACAAAAAAGGTTTCGATT
TTTGCTTCAGAAGATGGTATTATTCATACCAATCCCAAATATGATGGTGCCAATATTATTCCGAAGCAAACCGAGATTGC
TCAAATCTATCCTGATATTCAAAAAACAAGAAAAGTGTTAATCACCTATTATGCTTCTTCTGATGATGTTGTTTCTATGA
AAAAGGGGCAAACCGCTCGTCTTTCCTTGGAAAAAAAGGGAAATGACAAGGTTGTTATTGAAGGAAAAATTAACAATGTC
GCTTCATCAGCAACTACTACTAAAAAAGGAAATCTCTTTAAGGTTACTGCCAAAGTAAAGGTTTCTAAGAAAAATAGCAA
ACTCATCAAGTATGGTATGACAGGCAAGACAGTCACTGTCATTGATAAAAAGACTTATTTTGATTATTTCAAAGATAAAT
TACTGCATAAAATGGATAATTAG

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(160-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB/nlmE Streptococcus mutans UA159

100

100

1

Multiple sequence alignment