Detailed information NTG0160684

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: HSISS4_RS00495
• Genome accession: NZ_CP013216
• Coordinates: 83190..85640 (+)
• Length: 816 a.a.
• NCBI ID: WP_021143437.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain HSISS4
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 78190..90640

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HSISS4_RS00470 (HSISS4_00056)	ahpC	79087..79647 (-)	561	WP_002886340.1	alkyl hydroperoxide reductase subunit C	-
HSISS4_RS00475 (HSISS4_00057)	rpsB	79920..80687 (+)	768	WP_002886342.1	30S ribosomal protein S2	-
HSISS4_RS00480 (HSISS4_00058)	tsf	80798..81838 (+)	1041	WP_002886343.1	translation elongation factor Ts	-
HSISS4_RS00485 (HSISS4_00059)	-	81946..82416 (-)	471	WP_004182164.1	COG2426 family protein	-
HSISS4_RS00490 (HSISS4_00060)	-	82734..83189 (+)	456	WP_014633783.1	CtsR family transcriptional regulator	-
HSISS4_RS00495 (HSISS4_00061)	clpC	83190..85640 (+)	2451	WP_021143437.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
HSISS4_RS00500 (HSISS4_00062)	pbp3	85769..87025 (-)	1257	WP_059749066.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
HSISS4_RS00505 (HSISS4_00063)	pbp3	87170..88417 (-)	1248	WP_037620085.1	D-alanyl-D-alanine carboxypeptidase PBP3	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90190.57 Da
• Isoelectric Point: 6.1111

>NTDB_id=160684 HSISS4_RS00495 WP_021143437.1 83190..85640(+) (clpC) [Streptococcus salivarius strain HSISS4]
MTTYSRKMQAIFHRAQLEAERFGSPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIRAEEIETAAVLAMEKSPKDLSESDI
IDLRAQSHALGAMLQEAEGIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERYAGLS
KQDLKAIHDLRKPKKSKASGNFANMMQPPQSSTGELSDYTKDLTAVAESGALDPVIGREKEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVPEAIDILKGLRSSYEDYHRVTI
TDEAVEIAVKAAHRYLTSKNLPDSAIDLLDEASATVQGRIKKEAKREITPLDEALLSGDMKAAVKQYKASQKAKLPKPAL
VDANQIMQTLSRLSGIPVEKMTQADSKRYLNLEAELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAQDISHNHQAMQSRIMEELKKAYRPEFINRIDEKVV
FHSLEEEQLREIVKIMVKPLVSALAEKGIDLKFQPAALKHLAKDGYDVEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=160684 HSISS4_RS00495 WP_021143437.1 83190..85640(+) (clpC) [Streptococcus salivarius strain HSISS4]
ATGACGACATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAGGCAGAGCGTTTTGGAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCAGGATCTGTAGCCTACCTAACATTTACTGATTTTGAGGACC
GTATTCGTGCGGAAGAGATTGAGACCGCCGCTGTACTAGCGATGGAGAAAAGTCCAAAAGACTTGTCTGAATCCGATATT
ATCGATTTACGTGCACAGTCACATGCTTTAGGGGCTATGTTGCAAGAGGCAGAGGGAATTGCTAGTGTGACTGGTGCTGT
AGAGGTAGGGTCTGAACATGTATTGATGGCCTTCCTTCTTCATAAGGATTTGATGGTTTGTCGTCTCCTTGAAGTTGCTG
GTTTTCAATATAAGGATGACAGCGATAAGCCTCGTATTATCGATTTACGACGTTCTTTGGAGCGTTACGCAGGTCTTAGT
AAGCAAGATTTGAAGGCCATTCATGACCTTCGTAAGCCTAAAAAATCAAAGGCATCAGGAAATTTTGCTAATATGATGCA
GCCTCCTCAATCTTCTACTGGGGAACTGTCAGATTATACCAAAGACTTAACGGCAGTAGCCGAATCAGGTGCTCTTGATC
CTGTTATTGGACGTGAGAAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAACCCAGTTCTTGTG
GGTGAAGCAGGTGTTGGTAAGACGGCACTTGCGCTTGGCTTAGCACAGCGTATTGCTTCAGGCGAAGTACCTTTTGAGTT
GGCTGATATGCGTATCTTAGAGCTTGATATGATGAGTGTGGTTGCAGGAACACGTTTCCGTGGCGATTTCGAAGAACGTA
TGAATCAGATCATTGATGAGATTGAAGCTGATGGAAAAATCATTCTCTTTATTGACGAATTGCATACGATTATCGGTTCT
GGTTCAGGTATTGATAGCACCTTAGATGCGGCGAATATTTTGAAACCCGCTCTAGCACGTGGAACCCTTCATATGGTTGG
AGCAACTACTCAAGCTGAGTACCAGAAGCATATTGAAAAAGATGCAGCTCTTTCTCGTCGTTTTGCTAAAATTACAATTG
AGGAGCCAAGTGTACCTGAGGCGATTGATATTCTAAAAGGCCTACGGTCGTCTTATGAAGACTATCATCGTGTAACGATT
ACTGATGAGGCGGTTGAGATAGCAGTCAAGGCAGCCCACCGTTATTTGACGAGTAAAAACTTACCCGACTCTGCCATTGA
TCTTTTAGATGAAGCGAGTGCAACTGTTCAAGGTCGTATCAAAAAAGAAGCCAAACGTGAGATAACGCCTTTGGATGAAG
CACTTCTATCTGGTGATATGAAGGCTGCTGTTAAACAATATAAGGCTAGCCAAAAAGCAAAATTACCAAAACCTGCCTTG
GTAGATGCAAATCAGATTATGCAAACCCTTAGTCGTCTATCAGGTATTCCTGTTGAGAAGATGACACAGGCAGATAGCAA
GCGTTACTTGAATCTGGAAGCAGAGCTTCACAAACGTGTTATTGGTCAAGATGAAGCAGTTTCGGCGATTAGTCGTGCTA
TTCGTCGTAACCAGTCAGGTATTCGTACCGGAAAACGCCCGATTGGTTCCTTTATGTTCCTTGGCCCTACTGGTGTTGGT
AAGACAGAATTGGCCAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAGTCAGCTTTGCTTCGCTTTGACATGTCAGAATA
CATGGAAAAATTTGCGGCTAGCCGACTAAACGGTGCTCCTCCAGGTTACGTTGGATATGATGAGGGCGGTGAATTAACAG
AGAAAGTTCGCAATAAGCCTTACTCAGTTCTCCTCTTTGACGAGGTGGAAAAGGCTCACCCAGATATTTTCAACATCCTC
TTACAGGTTTTGGATGATGGTGTCTTGACGGATAGCCGAGGTCGTAAAGTTGACTTCTCAAATACCATTATCATTATGAC
TTCGAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACTGTTGGATTTGGTGCCCAAGACATTTCTCATAATCACCAAG
CTATGCAGTCACGTATCATGGAAGAACTTAAGAAGGCCTACCGTCCAGAGTTTATCAACCGTATTGATGAGAAGGTTGTC
TTCCATAGTCTAGAGGAAGAACAACTTCGTGAGATTGTCAAGATTATGGTGAAACCGTTGGTATCAGCTTTGGCTGAAAA
AGGGATTGACTTGAAATTCCAACCAGCTGCTCTCAAGCATTTAGCTAAAGATGGCTATGATGTTGAGATGGGTGCTCGTC
CATTACGTCGTACGATTCAAACTCAAGTGGAGGACAAGTTATCTGAGCTCTTACTAGGTGGTCAAGTAGTTAGTGGACAA
ACTCTTAAAATCGGCTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (378-457)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (108-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	95.098	100	0.951
clpC	Streptococcus thermophilus LMD-9	94.975	100	0.95
clpC	Streptococcus mutans UA159	73.039	100	0.73
clpC	Streptococcus pneumoniae TIGR4	67.402	100	0.674
clpC	Streptococcus pneumoniae Rx1	67.402	100	0.674
clpC	Streptococcus pneumoniae D39	67.402	100	0.674
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.344	100	0.507
clpC	Bacillus subtilis subsp. subtilis str. 168	47.145	100	0.475
clpE	Streptococcus mutans UA159	48.243	76.716	0.37